Searched for: subject:"Virus%5C+recombinant"
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document
Geutskens, S.B. (author), van der Eb, M.M. (author), Plomp, A.C. (author), Jonges, L.E. (author), Cramer, S.J. (author), Ensink, N.G. (author), Kuppen, P.J.K. (author), Hoeben, R.C. (author)
The host-immune response against adenoviruses forms a major obstacle for their use as gene therapy vectors for treatment of genetic defects. None the less, they are the preferred vectors for in vivo gene transfer in experimental gene therapy protocols for cancer. In this article we demonstrate the antitumor efficacy of adenovirus-mediated...
article 2000
document
Quax, P.H.A. (author), Lamfers, M.L.M. (author), Grimbergen, J.M. (author), Teeling, J. (author), Hoeben, R.C. (author), van Nieuw Amerongen, G.P. (author), van Hinsbergh, V.W.M. (author), Gaubius Instituut TNO (author)
The plasminogen activation (PA) system is involved in vascular remodelling. Modulating its activity in vascular cells might be a way to interfere in processes such as angiogenesis and restenosis. Adenoviral vectors have become a favourable tool for direct gene transfer into vascular cells. In the interest of using adenoviral vectors to modulate...
article 1996