Searched for: subject%3A%22Viability%22
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Gilsing, R. (author), Turetken, O. (author), Ozkan, B. (author), Slaats, F. (author), Adali, O.E. (author), Wilbik, A. (author), Berkers, F.T.H.M (author), Grefen, P. (author)
conference paper 2020
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Opsteegh, M. (author), Dam-Deisz, C. (author), de Boer, P. (author), DeCraeye, S. (author), Faré, A. (author), Hengeveld, P. (author), Luiten, R. (author), Schares, G. (author), van Solt-Smits, C. (author), Verhaegen, B. (author), Verkleij, T. (author), van der Giessen, J. (author), Wisselink, H.J. (author)
Consumption of meat containing viable tissue cysts is considered one of the main sources of human infection with Toxoplasma gondii. In contrast to fresh meat, raw meat products usually undergo processing, including salting and mixing with other additives such as sodium acetate and sodium lactate, which affects the viability of T. gondii. However...
article 2020
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Shekhar, A. (author), Prasanth, V. (author), Bauer, P. (author), Bolech, M. (author)
The economic viability of on-road wireless charging of electric vehicles (EVs) strongly depends on the choice of the inductive power transfer (IPT) system configuration (static or dynamic charging), charging power level and the percentage of road coverage of dynamic charging. In this paper, a case study is carried out to determine the expected...
article 2016
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Bosman, J. (author), van den Berg, H. (author), van der Mei, R. (author)
Service orchestration has become the predominant paradigm that enables businesses to combine and integrate services offered by third parties. For the commercial viability of orchestrated services, it is crucial that they are offered at sharp price-quality ratios. A complicating factor is that many attractive third-party services often show...
conference paper 2015
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van den Homberg, M.J.C. (author), Posthumus, A.L. (author)
Christian Aid, Cordaid, PVGS and Practical Action established a community-based early warning system for cross-border floods between India and Nepal in 45 Indian villages. The project will scale to 95 villages early 2016. The number of stakeholders and organizational levels of this system with four key elements (risk knowledge, monitoring and...
conference paper 2014
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Bastiaansen-Jenniskens, Y.M. (author), Siawash, M. (author), van de Lest, C.H.A. (author), Verhaar, J.A.N. (author), Kloppenburg, M. (author), Zuurmond, A.M. (author), Stojanovic-Susulic, V. (author), van Osch, G.J.V.M. (author), Clockaerts, S. (author)
Purpose: Osteoarthritis (OA) is associated with obesity in which altered fatty acid levels have been observed. We investigated whether the most common fatty acids in synovial fluid influence cartilage deterioration in OA. Design: Cartilage was obtained from OA patients undergoing total knee arthroplasty. Chondrocytes or cartilage explants were...
article 2013
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Posthumus, A.L. (author), de Boer, J. (author), Stroek C.M., (author)
Entrepreneurs with the ambition to structurally cater the Base of the Pyramid (BoP) market face two challenges. On the one hand, they need to ‘go local’ to ensure local ownership. On the other hand, they have to work towards a scalable business model. This paper presents a framework which combines the innovation phases with the challenges of...
conference paper 2013
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Nocker, A. (author), Fernández, P.S. (author), Montijn, R. (author), Schuren, F. (author)
The effect of desiccation on the viability of microorganisms is a question of great interest for a variety of public health questions and industrial applications. Although viability is traditionally assessed by plate counts, cultivation-independent methods are increasingly applied with the aim to gain more insight into why cells might not form...
article 2012
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van de Briel, R.J. (author), Pennings, J.L.A. (author), Baken, K.A. (author), Pronk, T.E. (author), Boorsma, A. (author), Gottschalk, R. (author), van Loveren, H. (author), TNO Kwaliteit van Leven (author)
Many chemicals can induce allergic contact dermatitis. Because evaluation of skin sensitizing potential by animal testing is prohibited for cosmetics, and screening of many chemicals is required within Registration, Evaluation, Authorisation and Restriction of Chemicals, urgent need exists for predictive in vitro assays to identify contact...
article 2010
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Nocker, A. (author), Richter-Heitmann, T. (author), Montijn, R. (author), Schuren, F. (author), Kort, R. (author), TNO Kwaliteit van Leven (author)
The preferential detection of cells with intact membranes by sample treatment with propidium monoazide (PMA) in combination with PCR amplification is gaining in popularity. This study evaluates the effect of PMA on 454 pyrosequencing profiles of environmental water samples from a canal in Amsterdam and seawater (with sediment) left untreated or...
article 2010
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Kuhlmann, K.F.D. (author), van Geer, M.A. (author), Bakker, C.T. (author), Dekker, J.E.M. (author), Havenga, M.J.E. (author), Oude Elferink, R.P.J. (author), Gouma, D.J. (author), Bosma, P.J. (author), Wesseling, J.G. (author), TNO Kwaliteit van Leven (author)
Survival of patients with pancreatic cancer is poor. Adenoviral (Ad) gene therapy employing the commonly used serotype 5 reveals limited transduction efficiency due to the low amount of coxsackie-adenovirus receptor on pancreatic cancer cells. To identify fiber-chimeric adenoviruses with improved gene transfer, a library of Ad vectors based on...
article 2009
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Zvinavashe, E. (author), van den Berg, H. (author), Soffers, A.E.M.F. (author), Vervoort, J. (author), Freidig, A. (author), Murk, A.J. (author), Rietjens, I.M.C.M. (author), TNO Kwaliteit van Leven (author)
Quantitative structure-activity relationship (QSAR) models are expected to play a crucial role in reducing the number of animals to be used for toxicity testing resulting from the adoption of the new European Union chemical control system called Registration, Evaluation, and Authorization of Chemicals (REACH). The objective of the present study...
article 2008
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Wortelboer, H.M. (author), Balvers, M.G.J. (author), Usta, M. (author), van Bladeren, P.J. (author), Cnubben, N.H.P. (author), TNO Kwaliteit van Leven (author)
The interactions of three heavy metal-containing compounds, cisplatin (CDDP), arsenic trioxide (As2O3), and mercury dichloride (HgCl2), with the multidrug resistance transporters MRP1 and MRP2 and the involvement of glutathione (GSH)-related processes herein were investigated. In Madin-Darby canine kidney cells stably expressing MRP1 or MRP2,...
article 2008
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Tanase, D. (author), Komen, N. (author), Draaijer, A. (author), Lange, J.F. (author), Kleinrensink, G.J. (author), Jeekel, J. (author), French, P.J. (author), TNO Kwaliteit van Leven (author), KvL (author)
Leakage at the site of an anastomosis is the main, yet unsolved reason for mortality in abdominal surgery. Every year, a large number of patients die due to anastomotic leakage after surgery. An objective aid to monitor the anastomotic site pre- and postoperatively and detect leakage at an early stage, is needed. Therefore, a miniature, wireless...
conference paper 2008
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TNO Kwaliteit van Leven (author), Kort, R. (author), Keijser, B.J. (author), Caspers, M.P.M. (author), Schuren, F.H. (author), Montijn, R. (author)
Background: In bacteriology, the ability to grow in selective media and to form colonies on nutrient agar plates is routinely used as a retrospective criterion for the detection of living bacteria. However, the utilization of indicators for bacterial viability-such as the presence of specific transcripts or membrane integrity-would overcome bias...
article 2008
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TNO Kwaliteit van Leven (author), Abildayeva, K. (author), Berbée, J.F.P. (author), Blokland, A. (author), Jansen, P.J. (author), Hoek, F.J. (author), Meijer, O. (author), Lütjohann, D. (author), Gautier, T. (author), Pillot, T. (author), Vente, J.de (author), Havekes, L.M. (author), Ramaekers, F.C.S. (author), Kuipers, F. (author), Rensen, P.C.N. (author), Mulder, M. (author)
The H2 allele of APOC1, giving rise to increased gene expression of apolipoprotein C-I (apoC-I), is in genetic disequilibrium with the APOE4 allele and may provide a major risk factor for Alzheimer's disease (AD). We found that apoC-I protein is present in astrocytes and endothelial cells within hippocampal regions in both human control and AD...
article 2008
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Hendriksen, P.J.M. (author), Freidig, A.P. (author), Jonker, D. (author), Thissen, U. (author), Bogaards, J.J.P. (author), Mumtaz, M.M. (author), Groten, J.P. (author), Stierum, R.H. (author), TNO Kwaliteit van Leven (author)
The present research aimed to study the interaction of three chemicals, methyl mercury, benzene and trichloroethylene, on mRNA expression alterations in rat liver and kidney measured by microarray analysis. These compounds were selected based on presumed different modes of action. The chemicals were administered daily for 14 days at the Lowest...
article 2007
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Verloove-Vanhorick, S.P. (author), TNO Kwaliteit van Leven (author)
Due to ever-improving medical technology over the course of the last century, the limit of viability has been lowered from around 32 weeks of gestation, first to 28 weeks and, in recent decades, to as low as less than 24 weeks. Long-term follow-up studies (Project on Preterm and Small-for- Gestational-Age Infants, Leiden Follow-up Project on...
article 2006
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TNO Defensie en Veiligheid (author), Kieboom, J. (author), Kusumaningrum, H.D. (author), Tempelaars, M.H. (author), Hazeleger, W.C. (author), Abee, T. (author), Beumer, R.R. (author)
Growing microorganisms on dry surfaces, which results in exposure to low water activity (aw), may change their normal morphology and physiological activity. In this study, the morphological changes and cell viability of Salmonella enterica serovar Enteritidis challenged to low a w were analyzed. The results indicated that exposure to reduced aw...
article 2006
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Zuang, V. (author), Alonso, M.A. (author), Botham, P.A. (author), Eskes, C. (author), Fentem, J. (author), Liebsch, M. (author), van de Sandt, J.J.M. (author), TNO Kwaliteit van Leven (author)
article 2005
Searched for: subject%3A%22Viability%22
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