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Schols, R.M. (author), Alic, L. (author), Beets, G.L. (author), Breukink, S.O. (author), Wieringa, F.P. (author), Stassen, L.P.S. (author)In colorectal surgery, detecting ureters and mesenteric arteries is of utmost importance to prevent iatrogenic injury and to facilitate intraoperative decision making. A tool enabling ureter- and artery-specific image enhancement within (and possibly through) surrounding adipose tissue would facilitate this need, especially during laparoscopy....article 2015
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Hemizygous deletion of CTGF/CCN2 does not suffice to prevent fibrosis of the severely injured kidneyFalke, L.L. (author), Dendooven, A. (author), Leeuwis, J.W. (author), Nguyen, T.Q. (author), van Geest, R.J. (author), van der Giezen, D.M. (author), Broekhuizen, R. (author), Lyons, K. (author), Stoop, R. (author), Kemperman, H. (author), Schlingemann, R. (author), Joles, J.A. (author), Goldschmeding, R. (author)Background: Connective Tissue Growth Factor (CTGF/CCN2) is an important mediator of kidney fibrosis. Previous observations indicated that attenuation of CCN2 expression sufficed to alleviate early kidney damage. However, little is known about the role of CCN2 in fibrosis of severely damaged and more chronically injured kidneys. Therefore, we...article 2012