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Patel, N. (author), Adelman, D.C. (author), Anagnostou, K. (author), Baumert, J.L. (author), Blom, W.M. (author), Campbell, D.E. (author), Chinthrajah, R.S. (author), Mills, E.N.C. (author), Javed, B. (author), Purington, N. (author), Remington, B.C. (author), Sampson, H.A. (author), Smith, A.D. (author), Yarham, R.A.R. (author), Turner, P.J. (author)Background Eliciting doses (EDs) (eg, ED01 or ED05 values, which are the amounts of allergen expected to cause objective symptoms in 1% and 5% of the population with an allergy, respectively) are increasingly being used to inform allergen labeling and clinical management. These values are generated from food challenge, but the frequency of...article 2021
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Blink, M. (author), Buitenkamp, T.D. (author), van Wouwe, J.P. (author), van Wering, E.R. (author), van der Velden, V.H.J. (author), Zwaan, C.M. (author), TNO Kwaliteit van Leven (author)Children with Down syndrome (DS) have an increased risk for developing both acute myeloid as well as acute lymphoblastic leukemia. These leukemias differ in clinical characteristics and biology compared to leukemias in non-DS children. Moreover, children with DS have an increased risk of side-effects from cytostatic therapy, which complicates...article 2009
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van Doorn, M.B.A. (author), Espirito Santo, S.M. (author), Meijer, P. (author), Kamerling, I.M. (author), Schoemaker, R.C. (author), Dirsch, V. (author), Vollmar, A. (author), Haffner, T. (author), Gebhardt, R. (author), Cohen, A.F. (author), Princen, H.M. (author), Burggraaf, J. (author), TNO Kwaliteit van Leven (author)Background: Epidemiologic studies suggest that garlic may have beneficial effects on risk factors associated with cardiovascular disease (CVD). However, these findings are not unambiguously supported by randomized placebo-controlled clinical trials. Objective: We sought to investigate the effects of a chemically well-characterized garlic...article 2006