Searched for: subject%3A%22Ultracentrifugation%22
(1 - 3 of 3)
TNO Kwaliteit van Leven (author), Kypreos, K.E. (author), van Dijk, K.W. (author), Havekes, L.M. (author), Zannis, V.I. (author)
To identify the residues in the carboxyl-terminal region 260-299 of human apolipoprotein E (apoE) that contribute to hypertriglyceridemia, two sets of conserved, hydrophobic amino acids between residues 261 and 283 were mutated to alanines, and recombinant adenoviruses expressing these apoE mutants were generated. Adenovirus-mediated gene...
article 2005
Jong, M.C. (author), van Ree, J.H. (author), Dahlmans, V.E.H. (author), Frants, R.R. (author), Hofker, M.H. (author), Havekes, L.M. (author), TNO Preventie en Gezondheid (author)
The function of apolipoprotein (apo) C1 in vivo is not clearly defined. Because transgenic mice overexpressing human apoC1 show elevated triacylglycerol (TG) levels, an as yet unknown role for apoC1 in TG metabolism has been suggested. Here we investigated directly the effect of the complete absence of apoC1 on very-low-density lipoprotein (VLDL...
article 1997
Offers, S. (author), Bentvelzen, P. (author), Radiobiologisch Instituut TNO (author)
article 1971