Searched for: subject%3A%22Trial%22
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Wissingh, B. (author), Ravesteijn, D. (author), Schwartz, R.S. (author)
This paper presents field trial results of two combined use cases with different QoS requirements: (1) a transport vertical Smart Junction use case; and (2) a healthcare vertical Paramedic Support use case. We focus on slicing prioritization configured in the RAN, at the gNB level, to guarantee QoS requirements for the combined use cases. We...
conference paper 2022
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Michielsen, C.C.J.R. (author), Hangelbroek, R.W.J. (author), Bragt, M.C.E. (author), Verheij, E.R. (author), Wopereis, S. (author), Mensink, R.P. (author), Afman, L.A. (author)
Scope: The drug fenofibrate and dietary fish oils can effectively lower circulating triglyceride (TG) concentrations. However, a detailed comparative analysis of the effects on the plasma metabolome is missing. Methods and Results: Twenty overweight and obese subjects participate in a double-blind, cross-over intervention trial and receive in a...
article 2022
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Westerneng, M. (author), de Jonge, A. (author), van Baar, A.L. (author), Witteveen, A.B. (author), Jellema, P. (author), Paarlberg, K.M. (author), Rijnders, M. (author), van der Horst, H.E. (author)
Background: Third-trimester routine ultrasounds are increasingly offered to monitor fetal growth. In addition to limited evidence for its clinical effectiveness, little is known about its importance for pregnancy-specific anxiety and mother-to-infant bonding. Methods: 1275 low-risk women participated in a Dutch nationwide pragmatic cluster...
article 2022
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Coert, R.M.H. (author), Timmis, J.K. (author), Boorsma, A (author), Pasman, W.J. (author)
Background: Conventional clinical trials are essential for generating high-quality evidence by measuring the efficacy of interventions in rigorously controlled clinical environments. However, their execution can be expensive and time-consuming. In addition, clinical trials face several logistical challenges regarding the identification,...
article 2021
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Versluis, A. (author), Knulst, A.C. (author), Michelsen-Huisman, A.D. (author), Houben, G.F. (author), Blom, W.M. (author), Le, T.M. (author), van Os-Medendorp, H. (author)
article 2021
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van Verseveld, M.D.A. (author), Fekkes, M. (author), Fukkink, R.G. (author), Oostdam, R.J. (author)
This study investigates the effectiveness of the PRIMA antibullying program for elementary education using a cluster-randomized trial with two experimental conditions (with and without student lessons) and a control group. Students of 31 schools participated in the study (N = 3,135; Mage = 10 years). Multilevel regression analyses demonstrated...
article 2021
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Sandin, K. (author), Gjengedal, R.G.H. (author), Osnes, K. (author), Hannisdal, M. (author), Berge, T. (author), Leversen, J.S.R. (author), Røv, L.G. (author), Lagerveld, S. (author), Blonk, R. (author), Nordahl, H.M. (author), Shields, G. (author)
Background: Common mental disorders such as depression and anxiety are major contributors to the global burden of disease. Affected individuals suffer reduced quality of life, impaired functioning and reduced capacity to work. Maintaining employment is an important determinant for health and wellbeing, and the economic impact of depression and...
article 2021
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Ragamin, A. (author), Fieten, K.B. (author), Tupker, R.A. (author), de Wit, J. (author), van Mierlo, M.M.F. (author), Jansen, M.S. (author), Bronner, M.B. (author), Schappin, R. (author), Schuren, F.H.J. (author), Romeijn, M.L.E. (author), Arents, B.W.M. (author), Suzanne, (author), Polinder, S. (author), de Graaf, M. (author), Rustemeyer, T. (author), Schuttelaar, M.L.A. (author), Pasmans, S.G.M.A. (author)
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects 10 to 20% of children and between 2 and 15% of the adults in Western Europe. Since 2000, therapeutic clothing or functional textiles based on silver or chitosan as antibacterial agents were introduced for AD. These agents aim to reduce skin colonization with...
article 2021
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Patel, N. (author), Adelman, D.C. (author), Anagnostou, K. (author), Baumert, J.L. (author), Blom, W.M. (author), Campbell, D.E. (author), Chinthrajah, R.S. (author), Mills, E.N.C. (author), Javed, B. (author), Purington, N. (author), Remington, B.C. (author), Sampson, H.A. (author), Smith, A.D. (author), Yarham, R.A.R. (author), Turner, P.J. (author)
Background Eliciting doses (EDs) (eg, ED01 or ED05 values, which are the amounts of allergen expected to cause objective symptoms in 1% and 5% of the population with an allergy, respectively) are increasingly being used to inform allergen labeling and clinical management. These values are generated from food challenge, but the frequency of...
article 2021
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van Santen, J. (author), Dröes, R.M. (author), Twisk, J.W.R. (author), Blanson Henkemans, O.A. (author), van Straten, A. (author), Meiland, F.J.M. (author)
Objectives: Physical activity in people with dementia (PwD) may enhance physical and mental functioning. Exergaming, which combines physical exercise with cognitive stimulation in a gaming environment, was developed to overcome barriers in performing physical activities. We evaluated the effects of exergaming in day care centers (DCCs) for PwD...
article 2021
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Austin, P.C. (author), White, I.R. (author), Lee, D.S. (author), van Buuren, S. (author)
Missing data is a common occurrence in clinical research. Missing data occurs when the value of the variables of interest are not measured or recorded for all subjects in the sample. Common approaches to addressing the presence of missing data include complete-case analyses, in which subjects with missing data are excluded, or mean-value...
article 2021
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Grappiolo, C. (author), Pruim, R. (author), Faeth, M. (author), de Heer, P.B.U.L. (author)
Product customisation is a topic of growing interest in Smart Manufacturing. Allowing customers to design intended products brings additional challenges to the manufacturing task, such as the increase in flexibility of the assembly theatre, the compilation of assembly instructions for possibly unique products, and stress-related risks for human...
article 2021
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Humalda, J.K. (author), Klaassen, G. (author), de Vries, H. (author), Meuleman, Y. (author), Verschuur, L.C. (author), Straathof, E.J.M. (author), Laverman, G.D. (author), Bos, W.J.W. (author), van der Boog, P.J.M. (author), Vermeulen, K.M. (author), Blanson Henkemans, O.A. (author), Otten, W. (author), de Borst, M.H. (author), van Dijk, S. (author), Navis, G.J. (author)
Rationale & objective: Patients with chronic kidney disease (CKD) are particularly sensitive to dietary sodium. We evaluated a self-management approach for dietary sodium restriction in patients with CKD. Study design: Randomized controlled trial. Setting & participants: Nephrology outpatient clinics in 4 Dutch hospitals. 99 adults with CKD...
article 2020
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Hellingrath, B. (author), Widera, A. (author), Bonnamour, M.C. (author), Lund, D. (author), Fonio, C. (author), Stolk, D.J. (author), Dubost, L. (author), Pasedag, K. (author), Gerevini, M. (author), Zwęgliński, T. (author), Friedemann, M. (author)
Describes a pragmatic methodology for the assessment of innovative solutions in the area of crisis management. The results of this project together with this CWA will be used to establish a methodology that will: — enable practitioners to systematically assess the added value of an innovative solution; — enhance dialogue and co-operation among...
report 2020
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Offringa, A. (author), Montijn, R. (author), Singh, S. (author), Paul, M. (author), Pinto, Y.M. (author), Pinto-Sietsma, S.J. (author)
The SARS-CoV-2 pandemic is a healthcare crisis caused by insufficient knowledge applicable to effectively combat the virus. Therefore, different scientific discovery strategies need to be connected, to generate a rational treatment which can be made available as rapidly as possible. This relies on a solid theoretical understanding of the...
article 2020
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Pot, M. (author), Paulussen, T.G. (author), Ruiter, R.A. (author), Eekhout, I. (author), de Melker, H.E. (author), Spoelstra, M.E. (author), van Keulen, H.M. (author)
article 2020
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Pot, M. (author), Paulussen, T.G. (author), Ruiter, R.A. (author), Hofstra, M. (author), van Keulen, H.M. (author)
Background: In the Netherlands, human papillomavirus (HPV) vaccination uptake remains low. To improve informed decision making (IDM) and HPV vaccination acceptability, we systematically developed an interactive, web-based tailored intervention to which mothers of Dutch girls were invited to participate. Objective: The aim of this study was to...
article 2020
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Coenen, P. (author), Robroek, S.J.W. (author), van der Beek, A.J. (author), Boot, C.R.L. (author), van Lenthe, F.J. (author), Burdorf, A. (author), Oude Hengel, K.M. (author)
Background: This individual patient data (IPD) meta-analysis aimed to investigate socioeconomic inequalities in effectiveness on healthy behavior of, and compliance to, workplace health promotion programs. Methods: Dutch (randomized) controlled trials were identified and original IPD were retrieved and harmonized. A two-stage meta-analysis was...
article 2020
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Schoen, E.D. (author), Wopereis, S. (author)
BACKGROUND: Parallel intervention studies involving volunteers usually require a procedure to allocate the subjects to study-arms. Statistical models to evaluate the different outcomes of the study-arms will include study-arm as a factor along with any covariate that might affect the results. To ensure that the effects of the covariates are...
article 2020
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Hoevenaars, F.P.M. (author), Berendsen, C.M.M. (author), Pasman, W.J. (author), van den Broek, T.J. (author), Barrat, E. (author), de Hoogh, I.M. (author), Wopereis, S. (author)
In public health initiatives, generic nutrition advice (GNA) from national guidelines has a limited effect on food-intake improvement. Personalized nutrition advice (PNA) may enable dietary behavior change. A monocentric, randomized, parallel, controlled clinical trial was performed in males (n = 55) and females (n = 100) aged 25 to 70 years....
article 2020
Searched for: subject%3A%22Trial%22
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