Searched for: subject%3A%22Toxic%255C%2Bmaterials%22
(1 - 13 of 13)
document
Sharma, M.K. (author), Wieringa, F.P. (author), Frijns, A.J.H. (author), Kooman, J.P. (author)
Introduction: End-stage renal disease (ESRD) patients depend on dialysis for removal of toxic waste products, fluid overload relief and maintenance of electrolyte balance. Dialysis prolongs millions of lives. To some extent, ESRD has become a manageable disease with a steadily growing dialysis population of increasing average age and associated...
article 2016
document
Koopman, F.W. (author), de Winde, J.H. (author), Ruijssenaars, H.J. (author), TNO Kwaliteit van Leven (author)
The solvent-tolerant bacterium Pseudomonas putida S12 was engineered to efficiently utilize the C1 compounds methanol and formaldehyde as auxiliary substrate. The hps and phi genes of Bacillus brevis, encoding two key steps of the ribulose monophosphate (RuMP) pathway, were introduced to construct a pathway for the metabolism of the toxic...
article 2009
document
Tukker, A. (author), Buist, H. (author), van Oers, L. (author), van der Voet, E. (author), TNO Bouw en Ondergrond (author)
The EU Commission's Services asked TNO and CML to perform a study into the risks of the present uses of lead over time, as an input to a discussion on the need of a further reduction of the use of this material. The study was set up as a substance flow analysis to analyse trends in uses and emissions of lead in Europe between 2000 and 2030. The...
article 2006
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Nijkamp, K. (author), van Luijk, N. (author), de Bont, J.A.M. (author), Wery, J. (author), TNO Kwaliteit van Leven TNO Voeding (author)
A Pseudomonas putida S12 strain was constructed that efficiently produced thefine chemical cinnamic acid from glucose or glycerol via the central metabolite phenylalanine. The gene encoding phenylalanine ammonia lyase from the yeast Rhodosporidium toruloides was introduced. Phenylalanine availability was the main bottleneck in cinnamic acid...
article 2005
document
Bombelli, V. (author), Maree, A.G.M. (author), Caramelli, F. (author), TNO Defensie en Veiligheid (author)
Commercial pressure on users and suppliers of space systems is forcing industry to reduce operational time and costs on ground and to increase reliability of operations in orbit. One opportunity has been identified in the use of non-toxic alternatives to established state-of the art propellants for spacecraft and orbital vehicles. Due to the...
conference paper 2005
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Brouwer, D.H. (author), Gijsbers, J.H.J. (author), Lurvink, M.W.M. (author), TNO Voeding (author)
Recently, toxicological and epidemiological studies on health effects related to particle exposure suggest that 'ultrafine particles' (particles with an aerodynamic diameter of <100 nm) may cause severe health effects after inhalation. Although the toxicological mechanisms for these effects have not yet been explained, it is apparent that...
article 2004
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Wolken, W.A.M. (author), Tramper, J. (author), van der Werf, M.J. (author), Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author)
Many organisms have the ability to form spores, a remarkable phase in their life cycles. Compared with vegetative cells, spores have several advantages (e.g. resistance to toxic compounds, temperature, desiccation and radiation) making them well suited to various applications. The applications of spores that first spring to mind are bio-warfare...
article 2003
document
van Baar, B.L.M. (author), Hulst, A.G. (author), de Jong, A.L. (author), Wils, E.R.J. (author), Prins Maurits Laboratorium TNO (author)
A method earlier developed for the mass spectrometric (MS) identification of tetanus toxin (TTx) was applied to botulinum toxins type A and B (BTxA and BTxB). Botulinum toxins are extremely neurotoxic bacterial toxins, likely to be used as biological warfare agent. Biologically active BTxA and BTxB are comprised of a protein complex of the...
article 2002
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Fick, M. (author), Schiebener, P. (author), Moerel, J.L.P.A. (author), van den Berg, R.P. (author), Sanders, H.M. (author), Welland-Veltmans, W.H.M. (author), Prins Maurits Laboratorium TNO (author)
The benefits of advanced HNF monopropellants are discussed. The areas of consideration comprise the operational and performance aspects, the general handling, the benign less-toxic characteristics and the envisaged reduction of manufacturing, test and operational costs. The recently proposed developments and applications of advanced...
conference paper 2001
document
Cherrie, J.W. (author), Brouwer, D.H. (author), Roff, M. (author), Vermeulen, R. (author), Kromhout, H. (author)
Fluorescent tracers provide a way of simultaneously assessing the mass of a contaminant hazardous substance on the surface of the skin of a worker and the area of skin exposed. These parameters, along with the duration of exposure and the estimated contaminant concentration in the skin contamination layer, can be used to calculate the likely...
article 2000
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Kromhout, H. (author), Hoek, F. (author), Uitterhoeve, R. (author), Huijbers, R. (author), Overmars, R.F. (author), Anzion, R. (author), Vermeulen, R. (author)
Dermal exposure to anti-neoplastic drugs has been suggested as a potentially important route of exposure of hospital workers. Three small-scale workplace surveys were carried out in several hospitals focusing on contamination by leakage from IV infusion systems; contamination by spilled urine of patients treated with anti-neoplastic drugs and...
article 2000
document
Zhang, S.Y. (author), Wang, J.S. (author), Jiang, Z.C. (author), Chen, M.X. (author)
As a result of seriously polluted raw water sources, some water- treatment plants in China are intending to apply the biofilm process as a pretreatment prior to the traditional drinking water-treatment systems. These polluted raw waters contain higher total organic matter and ammonium than unpolluted waters. It has been reported that synthetic...
article 2000
document
Gimeno, S. (author), Bowmer, C.T. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The assessment of risks to the aquatic environment in the European Union is generally based on a comparison of Predicted Environmental Concentrations (PEC) with Predicted No Effect Concentrations (PNEC) for surrogate, or `representative', organisms of the receiving waters. Such risk assessments are required for new and priority existing...
conference paper 1999
Searched for: subject%3A%22Toxic%255C%2Bmaterials%22
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