Searched for: subject:"Thyrotropin"
(1 - 9 of 9)
document
Zwaveling-Soonawala, N. (author), Trotsenburg, A.S. (author), Verkerk, P.H. (author)
Context. In central hypothyroidism (CeH) free thyroxine (FT4) concentrations are low while TSH concentrations may be low, normal or even slightly elevated due to reduced bioactivity. Congenital CeH (CCeH) may be isolated or part of multiple pituitary hormone deficiency (MPHD). Objective. To test our hypotheses that (1) TSH concentrations have a...
article 2018
document
Zwaveling-Soonawala, N. (author), Trotsenburg, A.S. (author), Verkerk, P.H. (author)
Congenital hypothyroidism (CH) may be of thyroidal (CHT) or central origin (CHC). Worldwide, most neonatal screening programs are TSH based and effectively detect CHT. Only a few screening programs measure total or free T4 and TSH simultaneously or stepwise, enabling detection of CHT as well as CHC. A frequently used argument against screening...
article 2015
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Vis, D.J. (author), Westerhuis, J.A. (author), Hoefsloot, H.C.J. (author), Roelfsema, F. (author), van der Greef, J. (author), Hendriks, M.M.W.B. (author), Smilde, A.K. (author)
Relations among hormone serum concentrations are complex and depend on various factors, including gender, age, body mass index, diurnal rhythms and secretion stochastics. Therefore, endocrine deviations from healthy homeostasis are not easily detected or understood. A generic method is presented for detecting regulatory relations between...
article 2014
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TNO Kwaliteit van Leven (author), Kempers, M.J.E. (author), Lanting, C.I. (author), van Heijst, A.F.J. (author), van Trotsenburg, A.S.P. (author), Wiedijk, B.M. (author), de Vijlder, J.J.M. (author), Vulsma, T. (author)
Context: The Dutch T4-TSH-TBG-based neonatal screening program detects patients with congenital hypothyroidism (CH) of thyroidal (CH-T) as well as central (CH-C) origin. The numbers and characteristics of true-positive and false-positive referrals will differ from other, predominantly TSH-based, screening methods. Objective: The present study...
article 2006
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Lanting, C.I. (author), van Tijn, D.A. (author), Loeber, J.G. (author), Vulsma, T. (author), de Vijlder, J.J.M. (author), Verkerk, P.H. (author), TNO Preventie en Gezondheid (author)
Context. Since the introduction of screening for congenital hypothyroidism (CH) in 1974, the optimal laboratory strategy has been the subject of debate. Objective. To assess the clinical effectiveness and cost-effectiveness of various types of thyroxine (T4)-based strategies to screen for CH. Design, Setting, and Participants. In the Netherlands...
article 2005
document
van Tijn, D.A. (author), de Vijlder, J.J.M. (author), Verbeeten Jr., B. (author), Verkerk, P.H. (author), Vulsma, T. (author), TNO Preventie en Gezondheid (author)
Due to the high frequency of concurrent pituitary hormone deficiencies, congenital hypothyroidism (CH) of central origin (CH-C) is a life-threatening disorder. Yet only a minority of these patients are detected by neonatal CH screening programs worldwide. We conducted a prospective multicenter study involving a 2-yr cohort of neonatally...
article 2005
document
den Ouden, A.L. (author), Kok, J.H. (author), Verkerk, P.H. (author), Brand, R. (author), Verloove-Vanhorick, S.P. (author), TNO Preventie en Gezondheid (author)
Transient neonatal hypothyroxinemia is very common in preterm infants. The literature on the effect of this hypothyroxinemia is, however, controversial, and large or long-term follow-up studies are not available. In a nationwide prospective follow-up study on very preterm and (or) very low birth weight infants (n = 717), we studied the...
article 1996
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Qvigstad, E. (author), Verloove-Vanhorick, S.P. (author), Ens-Dokkum, M.H. (author), Schreuder, A.M. (author), Veen, S. (author), Brand, R. (author), Oostdijk, W. (author), Ruys, J.H. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
To predict height at five years in a cohort of 565 very preterm and/or very low-birth-weight children, hypothesized growth determinants were subjected to discriminant analysis. Many neonatal parameters were not significantly associated with short stature at five years of age. A correct classification of stature (smaller/larger than the 10th...
article 1993
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Verkerk, P.H. (author), Derksen-Lubsen, G. (author), Vulsma, T. (author), Loeber, J.G. (author), de Vijlder, J.J.M. (author), Verbrugge, H.P. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
Doel. Evaluatie van de Nederlandse screening op congenitale hypothyreoïdie (CHT). Opzet. Descriptief. Plaats. Landelijk. Methoden. Gegevens over de screening in de periode 1 januari 1981-31 december 1990 werden verkregen van de entadministraties, van laboratoria en van kinderartsen naar wie kinderen met afwijkende uitslagen verwezen werden....
article 1993
Searched for: subject:"Thyrotropin"
(1 - 9 of 9)