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van de Ven, H.A. (author), Brouwer, S. (author), Koolhaas, W. (author), Goudswaard, A. (author), de Looze, M.P. (author), Kecklund, G. (author), Almansa, J. (author), Bültmann, U. (author), van der Klink, J.J.L. (author)In this cross-sectional study associations were examined between eight shift schedule characteristics with shift-specific sleep complaints and need for recovery and generic health and performance measures. It was hypothesized that shift schedule characteristics meeting ergonomic recommendations are associated with better sleep, need for recovery...article 2016
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Brouwer, D. (author), Boessen, R. (author), van Duuren-Stuurman, B. (author), Bard, D. (author), Moehlmann, C. (author), Bekker, C. (author), Fransman, W. (author), Entink, R.K. (author)Tiered or stepwise approaches to assess occupational exposure to nano-objects, and their agglomerates and aggregates have been proposed, which require decision rules (DRs) to move to a next tier, or terminate the assessment. In a desk study the performance of a number of DRs based on the evaluation of results from direct reading instruments was...article 2016
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de Graaff, J.C. (author), Pasma, W. (author), van Buuren, S. (author), Duijghuisen, J.J. (author), Nafiu, O.O. (author), Kheterpal, S. (author), van Klei, W.A. (author)Background: Although noninvasive blood pressure (NIBP) monitoring during anesthesia is a standard of care, reference ranges for blood pressure in anesthetized children are not available. We developed sex- and age-specific reference ranges for NIBP in children during anesthesia and surgery. Methods: In this retrospective observational cohort...article 2016
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- Blom, K.C.H. (author), Dol, H.S. (author), Kokkeler, A.B.J. (author), Smit, G.J.M. (author) conference paper 2016
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Friesen, M.C. (author), Wheeler, D.C. (author), Vermeulen, R. (author), Locke, S.J. (author), Zaebst, D.D. (author), Koutros, S. (author), Pronk, A. (author), Colt, J.S. (author), Baris, D. (author), Karagas, M.R. (author), Malats, N. (author), Schwenn, M. (author), Johnson, A. (author), Armenti, K.R. (author), Rothman, N. (author), Stewart, P.A. (author), Kogevinas, M. (author), Silverman, D.T. (author)Objectives: To efficiently and reproducibly assess occupational diesel exhaust exposure in a Spanish case-control study, we examined the utility of applying decision rules that had been extracted from expert estimates and questionnaire response patterns using classification tree (CT) models from a similar US study. Methods: First, previously...article 2016
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Hogervorst, M.A. (author), Toet, A. (author)Previously, we presented a method for applying daytime colours to fused nighttime (e.g., intensified and LWIR) imagery (Toet and Hogervorst, Opt.Eng. 51(1), 2012). Our colour mapping not only imparts a natural daylight appearance to multiband nighttime images but also enhances the contrast and visibility of otherwise obscured details. As a...conference paper 2016
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Schelvis, R.M.C. (author), Wiezer, N.M. (author), Blatter, B.M. (author), van Genabeek, J.A.G.M. (author), Oude Hengel, K.M. (author), Bohlneijer, E.T. (author), van der Beek, A.J. (author)Background The importance of process evaluations in examining how and why interventions are (un) successful is increasingly recognized. Process evaluations mainly studied the implementation process and the quality of the implementation (fidelity). However, in adopting this approach for participatory organizational level occupational health...article 2016
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Nelisse, R.M.L. (author), Vrouwenvelder, A.C.W.M. (author)Article 13 of the EU Directive on minimum safety requirements for tunnels in the Trans-European Road Network states that a “risk analysis, where necessary, shall be carried out” [1]. In the Netherlands, the risk of death for road users in a tunnel (internal risk) is calculated with a model for quantitative risk analysis, which is called “QRA...conference paper 2016
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- Klein Entink, R.H. (author), Bekker, C. (author), Fransman, W.F. (author), Brouwer, D.H. (author) article 2015
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Schrieks, I.C. (author), Heil, A.L. (author), Hendriks, H.F. (author), Mukamal, K.J. (author), Beulens, J.W. (author)OBJECTIVE: Moderate alcohol consumption is associated with a reduced risk of type 2 diabetes. This reduced risk might be explained by improved insulin sensitivity or improved glycemic status, but results of intervention studies on this relation are inconsistent. The purpose of this study was to conduct a systematic review and meta-analysis of...article 2015
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Vlaming, M.L. (author), van Duijn, E. (author), Dillingh, M.R. (author), Brands, R. (author), Windhorst, A.D. (author), Hendrikse, N.H. (author), Bosgra, S. (author), Burggraaf, J. (author), de Koning, M.C. (author), Fidder, A. (author), Mocking, J.A. (author), Sandman, H. (author), de Ligt, R.A. (author), Fabriek, B.O. (author), Pasman, W.J. (author), Seinen, W. (author), Alves, T. (author), Carrondo, M. (author), Peixoto, C. (author), Peeters, P.A. (author), Vaes, W.H. (author)Preclinical development of new biological entities (NBEs), such as human protein therapeutics, requires considerable expenditure of time and costs. Poor prediction of pharmacokinetics in humans further reduces net efficiency. In this study, we show for the first time that pharmacokinetic data of NBEs in humans can be successfully obtained early...article 2015
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Stubbé, H. (author), Badri, A. (author), Telford, R. (author), van der Hulst, A. (author)E-Learning Sudan (ELS) is a custom-built computer game that provides alternative learning opportunities to Sudanese children who are excluded from education. Unique in ELS is that children can learn mathematics, in their own remote village, without a teacher. This research study assessed the effectiveness of ELS through a pretest-posttest...conference paper 2015
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Lubeck, A.J.A. (author), Bos, J.E. (author), Stins, J.F. (author)Abstract Objective It is generally assumed that motion in motion images is responsible for increased postural sway as well as for visually induced motion sickness (VIMS). However, this has not yet been tested. To that end, we studied postural sway and VIMS induced by motion and still images. Method 15 Participants were exposed to motion- and...article 2015
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van der Voort, M.M. (author), van Wees, R.M.M. (author), Brouwer, S.D. (author), van der Jagt-Deutekom, M.J. (author), Verreault, J. (author)Forensic analysis of explosions consists of determining the point of origin, the explosive substance involved, and the charge mass. Within the EU fP7 project Hyperion, TNO developed the Inverse Explosion Analysis (TNO-IEA) tool to estïmate the charge mass and point of origin based on observed damage around an explosion. In this paper inverse...article 2015
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van Heijningen, M. (author), Hoogland, J.A. (author), de Hek, A.P. (author), van Vliet, F.E. (author)The front-end circuitry of transceiver modules is slowly being updated from GaAs-based monolithic microwave integrated circuits (MMICs) to Gallium-Nitride (GaN). Especially GaN power amplifiers and T/R switches, but also low-noise amplifiers (LNAs), offer significant performance improvement over GaAs components. Therefore it is interesting to...article 2015
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van der Voort, M.M. (author), van Wees, R.M.M. (author), Brouwer, S.D. (author), van der Jagt-Deutekom, M.J. (author), Verreault, J. (author)Forensic analysis of explosions consists of determining the point of origin, the explosive substance involved, and the charge mass. Within the EU FP7 project Hyperion, TNO developed the Inverse Explosion Analysis (TNO-IEA) tool to estimate the charge mass and point of origin based on observed damage around an explosion. In this paper inverse...conference paper 2015
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Cekli, H.E. (author), Joosten, R.F.D. (author), van de Water, W. (author)We stir wind-tunnel turbulence with an active grid that consists of rods with attached vanes. The time-varying angle of these rods is controlled by random numbers. We study the response of turbulence on the statistical properties of these random numbers. The random numbers are generated by the Gledzer-Ohkitani-Yamada shell model, which is a...article 2015
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van der Voort, M.M. (author), van Wees, R.M.M. (author), Brouwer, S.D. (author), van der Jagt-Deutekom, M.J. (author), Verreault, J. (author)Forensic analysis of explosions consists of determining the point of origin, the explosive substance involved, and the charge mass. Within the EU FP7 project Hyperion, TNO developed the Inverse Explosion Analysis (TNO-IEA) tool to estimate the charge mass and point of origin based on observed damage around an explosion. In this paper inverse...conference paper 2015
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- Taylor, S.L. (author), Houben, G.F. (author), Baumert, J.L. (author), Crevel, R.R.W.R. (author), Allen, K.J. (author), Dubois, A.E.J. (author), Knulst, A.C. (author), Remington, B.C. (author), Kruizinga, A.G. (author), Blom, W.M. (author), Brooke-Taylor, S. (author) article 2015
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Fonseca, R.M. (author), Kahrobaei, S.S. (author), van Gastel, L.J.T. (author), Leeuwenburgh, O. (author), Jansen, J.D. (author)With an increase in the number of applications of ensemble optimization (EnOpt) for production optimization, the theoretical understanding of the gradient quality has received little attention. An important factor that influences the quality of the gradient estimate is the number of samples. In this study we use principles from statistical...conference paper 2015