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Koopman, A.S. (author), Naf, M. (author), Baltrusch, S.J. (author), Kingma, I. (author), Rodriguez-Guerrero, C. (author), Babic, J. (author), de Looze, M.P. (author), van Dieën, J.H. (author)The number one cause of disability in the world is low-back pain, with mechanical loading as one of the major risk factors. To reduce mechanical loading, exoskeletons have been introduced in the workplace. Substantial reductions in back muscle activity were found when using the exoskeleton during static bending and manual materials handling....article 2020
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Deurloo, J.A. (author), Verkerk, P.H. (author)Objectives: Over the years, there has been much debate about the desirability and efficacy of screening for adolescent idiopathic scoliosis. To analyse the current evidence from a public health point of view a renewed evaluation of the literature was performed. Study design: Literature review. Methods: We performed two literature searches: from...article 2015
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Groenesteijn, L. (author), Ellegast, R.P. (author), Keller, K. (author), Krause, F. (author), Berger, H. (author), de Looze, M.P. (author)In the present study, we investigated the effect of office tasks on posture and movements in field settings, and the comfort rating for chair characteristics and correlation with type of task. The tasks studied were: computer work, telephoning, desk work and conversation. Postures, movements, chair part inclinations and comfort rating data were...article 2012
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Zenk, R. (author), Franz, M. (author), Bubb, H. (author), Vink, P. (author)For car manufacturers, seat comfort is becoming more important in distinguishing themselves from their competitors. Therefore, many studies on participative seat comfort are carried out. In this paper, an objective assessment approach is reported which evaluates the concept of "optimal load distribution", based on the identification of a close...article 2012
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van Dijk, C.E. (author), de Boer, M.R. (author), Koppes, L.L.J. (author), Roos, J.C. (author), Lips, P. (author), Twisk, J.W.R. (author), TNO Kwaliteit van Leven (author)Introduction: Studies on the association of vitamin D and bone mineral density (BMD) in adolescence and young adults have shown contrasting results. None of these studies have examined the course and baseline in vitamin D intake. The purpose of this study was to examine the association between baseline and the course of dietary vitamin D intake...article 2009
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van Dieën, J.H. (author), Putten, E.P. (author), Kingma, I. (author), de Looze, M.P. (author), TNO Kwaliteit van Leven (author)This study was designed to determine whether trunk extensor fatigue occurs during low-level activity and whether this is associated with a drop in muscle tissue oxygenation. Electromyography (EMG) feedback was used to impose constant activity in a part of the trunk extensor muscles. We hypothesized that electromyographic manifestations of...article 2009
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Faber, G.S. (author), Kingma, I. (author), Delleman, N. (author), van Dieën, J. (author)This study investigated the effects of ship motion on peak spinal loading during lifting. All measurements were done on a ship at sea. In 1-min trials, which were repeated over a wide range of sailing conditions, subjects lifted an 18 kg box five times. Ship motion, whole body kinematics, ground reaction forces and electromyography were measured...article 2008
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Brink, E. (author), Coxam, V. (author), Robins, S. (author), Wahala, K. (author), Cassidy, A. (author), Branca, F. (author), KvL (author)Background: Osteoporosis is a major health problem. It was hypothesized that isoflavone-containing products may be a potential alternative to hormone replacement therapy for preventing bone loss during the menopausal transition. Objective: The objective was to investigate whether the consumption of isoflavone-enriched foods for 1 y affects bone...article 2008
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Hoogendoorn, R.J.W. (author), Helder, M.N. (author), Kroeze, R.J. (author), Bank, R.A. (author), Smit, T.H. (author), Wuisman, P.I.J.M. (author), TNO Kwaliteit van Leven (author)STUDY DESIGN. Twelve goats were chemically degenerated and the development of the degenerative signs was followed for 26 weeks to evaluate the progression of the induced degeneration. The results were also compared with a previous study to determine the reproducibility. OBJECTIVES. The purpose of this study was determine whether this...article 2008
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Meijer, R. (author), Rodarius, C. (author), Adamec, J. (author), van Nunen, E. (author), van Rooij, L. (author), TNO Industrie en Techniek (author)In far-side impacts, the time span between the car-to-car impact and the occupant interaction with the interior is longer than 200 ms. In this time span, the reaction of the driver might affect the injury outcome significantly. The objective of this study was to demonstrate the differences between the active and passive human response and the...article 2008
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Hoogendoorn, R. (author), Doulabi, B.Z. (author), Huang, C.L. (author), Wuisman, P.I. (author), Bank, R.A. (author), Helder, M.N. (author), TNO Kwaliteit van Leven (author)Study Design. Caprine lumbar intervertebral discs (IVD) were collected from previous studies and categorized as normal, mildly, or severely degenerated. The biochemical composition and the RNA profiles present in both the nucleus pulposus (NP) and the anulus fibrosus (AF) were analyzed. Objective. To determine the molecular changes occurring in...article 2008
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TNO Kwaliteit van Leven (author), Hoogendoorn, R.J.W. (author), Lu, Z.F. (author), Kroeze, R.J. (author), Bank, R.A. (author), Wuisman, P.I. (author), Helder, M.N. (author)Introduction Degenerative disc disease and emerging biological treatment approaches Stem cell sources Integration of ASC-based regenerative medicine and surgery In vitro studies Animal models Cells in disc regeneration in vivo In vivo studies Perspective Conclusions Abstract New regenerative treatment strategies are being developed for...article 2008
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TNO Kwaliteit van Leven (author), Sivan, S.S. (author), Wachtel, E. (author), Tsitron, E. (author), Sakkee, N. (author), van der Ham, F. (author), Groot, J.de (author), Roberts, S. (author), Maroudas, A. (author)Knowledge of rates of protein turnover is important for a quantitative understanding of tissue synthesis and catabolism. In this work, we have used the racemization of aspartic acid as a marker for the turnover of collagen obtained from healthy and pathological human intervertebral disc matrices. We measured the ratio of the D- and L-isomers in...article 2008
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van Hamberg - Reenen, H.H. (author), Ariëns, G.A.M. (author), Blatter, B.M. (author), van Mechelen, W. (author), Bongers, P.M. (author), TNO Kwaliteit van Leven (author)The results of longitudinal studies reporting on the relation between physical capacity and the risk of musculoskeletal disorders have never been reviewed in a systematic way. The objective of the present systematic review is to investigate if there is evidence that low muscle strength, low muscle endurance, or reduced spinal mobility are...article 2007
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van Hamberg - Reenen, H.H. (author), Ariëns, G.A.M. (author), Blatter, B.M. (author), Twisk, J.W.R. (author), van Mechelen, W. (author), Bongers, P.M. (author), TNO Kwaliteit van Leven (author)Aims: To investigate the longitudinal relation between physical capacity (isokinetic lifting strength, static endurance of the back, neck, and shoulder muscles, and mobility of the spine) and low back, neck, and shoulder pain. Methods: In this prospective cohort study, 1789 Dutch workers participated. At baseline, isokinetic lifting strength,...article 2006
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TNO Kwaliteit van Leven (author), van Hamberg-Reenen, H.H. (author), Ariëns, G.A.M. (author), Blatter, B.M. (author), van der Beek, A.J. (author), Twisk, J.W.R. (author), van Mechelen, W. (author), Bongers, P.M. (author)Objectives: This study investigates whether an imbalance between physical capacity and exposure to work-related physical factors is associated with low-back, neck, or shoulder pain. Methods: Data of the longitudinal study on musculoskeletal disorders, absenteeism, stress, and health (SMASH), with a follow-up of 3 years (N=1789), were used. At...article 2006
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Verver, M.M. (author), van Hoof, J.F.A.M. (author), Oomens, C.W.J. (author), van de Wouw, N. (author), Wismans, J.S.H.M. (author)Objective. This paper describes the prediction of spinal forces in car occupants during vertical vibrations using a numerical multi-body occupant model. Background. An increasing part of the population is exposed to whole body vibrations in vehicles. In literature, vertical vibrations and low back pain are often related to each other. The cause...article 2003
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TNO Kwaliteit van Leven (author), Ariëns, G.A.M. (author), Bongers, P.M. (author), Hoogendoorn, W.E. (author), van der Wal, G. (author), van Mechelen, W. (author)Objectives This study investigates the relationship between physical and psychosocial load at work and sickness absence due to neck pain. Methods A prospective cohort study with a follow-up period of 3 years (1994-1998) was performed among a working population. At the beginning of the study, physical load at work was quantified by means of video...article 2002
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de Looze, M.P. (author), Steenhuizen, S. (author), Boeken-Kruger, M.C. (author), Baten, C.T.M. (author), Kingma, I. (author), van Dieën, J.H. (author)People who know the actual mass of an object to be lifted normally prepare themselves before attempting a lift to control the movement and to minimize low back loading. In this study, the trunk muscular reactions and low back torque were investigated in the situation in which the individual did not know the actual mass but only had some idea of...article 2000
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Hildebrandt, V.H. (author), Proper, K.I. (author), van den Berg, R. (author), Douwes, M. (author), van den Heuvel, S.G. (author), van Buuren, S. (author), TNO Preventie en Gezondheid (author)Objective. To determine the effectiveness of a special form of exercise therapy ('Cesar therapy') on self reported recovery and improvement of posture amongst patients with chronic aspecific lower back pain. Design. Prospective randomized controlled and blinded investigation. Method. After informed consent had been obtained, patients with...article 2000
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