- document
- Volkov, A. (author), Vasilevsky, V. (author), Lysenko, A. (author), van de Runstraat, A. (author), Matson, S. (author), Khotimskiy, V. (author) article 2012
- document
-
Sanchez Fernandez, E. (author), Goetheer, E.L.V. (author)This work describes the conceptual design of a novel separation process for CO2 removal from flue gas based on precipitating solvents. The process here described (DECAB) is an enhanced CO2 absorption based on the Le Chatelier's principle, which states that reaction equilibrium can be shifted by removing one of the constituents in the reaction. A...conference paper 2011
- document
-
Abu-Zahra, M.R.M. (author), Fernandez, E.S. (author), Goetheer, E.L.V. (author), TNO Industrie en Techniek (author)In this work, a perspective is given on the development lines for CO 2 post-combustion capture technology. Guidelines for cost reductions and suggestions for future research on solvent and process development are presented. By analyzing the post-combustion capture process in this work, it is evident that to achieve significant reduction of the...conference paper 2011
- document
-
Bandounas, L. (author), Ballerstedt, H. (author), de Winde, J.H. (author), Ruijssenaars, H.J. (author)Pseudomonas putida S12 is a promising platform organism for the biological production of substituted aromatic compounds due to its extreme tolerance towards toxic chemicals. Solvent or aromatic stress tolerance may be due to membrane modifications and efflux pumps; however in general, polyamines have also been implicated in stressed cells....article 2011
- document
-
Wijte, D. (author), van Baar, B.L.M. (author), Heck, A.J.R. (author), Altelaar, A.F.M. (author)To enhance target production from biocatalysts, it is necessary to thoroughly understand the molecular mechanisms involved in production, degradation, and, importantly, adaptation to the required environment. One such bacterium with high potential for biocatalysis is the solvent-tolerant bacteria Pseudomonas putida S12, which, among others, is...article 2011
- document
-
van den Berg, C. (author), Boon, F. (author), Roelands, C.P.M. (author), Bussmann, P.J.Th. (author), Goetheer, E.L.V. (author), Verdoes, D. (author), Wielen, L.A.M. (author)Most fermentation products have a feedback inhibiting effect on the host organism. In situ product recovery (ISPR) can be a means to overcome this product inhibition in fermentations. Particles such as solvent impregnated resins or capsules can be valuable tools for product recovery based on extraction. To evaluate, which kind of particle will...article 2010
- document
-
Grossiord, N. (author), Wouters, M.E.L. (author), Miltner, H.E. (author), Lu, K. (author), Loos, J. (author), Mele, B.V. (author), Koning, C.E. (author), TNO Industrie en Techniek (author)Several series of nanocomposites were prepared using a latex-based process, the main step of which consisted of mixing an aqueous suspension of exfoliated carbon nanotubes (CNTs) and a polymer latex. In the present work, a systematic study on the electrical properties of fully amorphous (polystyrene - PS) as well as semi-crystalline (isotactic...article 2010
- document
-
van den Berg, C. (author), Roelands, C.P.M. (author), Bussmann, P.J.Th. (author), Goetheer, E.L.V. (author), Verdoes, D. (author), van der Wielen, L.A.M. (author)Since the concept of solvent impregnated resins was introduced in the early 1980s, the technique has been applied to a limited amount of applications. The main disadvantage of the resins was that the amount of solvent inside was limited to approximately 1.5 ml/g polymer. A new generation of solvent impregnated resins is introduced. These...article 2009
- document
-
Hissink, A.M. (author), Kulig, B.M. (author), Kruse, J. (author), Freidig, A.P. (author), Verwei, M. (author), Muijser, H. (author), Lammers, J.H.C.M. (author), Mckee, R.H. (author), Owen, D.E. (author), Sweeney, L.M. (author), Salmon, F. (author), TNO Kwaliteit van Leven (author)This report describes a physiologically based pharmacokinetic model for cyclohexane and its use in comparing internal doses in rats and volunteers following inhalation exposures. Parameters describing saturable metabolism of cyclohexane are measured in rats and used along with experimentally determined partition coefficients. The model is...article 2009
- document
-
Wouters, M.E.L. (author), Craenmehr, E.G.M. (author), Tempelaars, K. (author), Fischer, H.R. (author), Stroeks, N. (author), van Zanten, J. (author), TNO Industrie en Techniek (author)Key properties of organic coatings, such as mechanical strength and solvent resistance, are greatly influenced by the structure of the polymeric binder. In general, a 3-dimensional polymeric network gives the best properties and therefore most performance coatings have a 3-dimensional network structure. However, 3-dimensional networks cannot...article 2009
- document
-
Lammers, J.H.C.M. (author), Emmen, H.H. (author), Muijser, H. (author), Hoogendijk, E.M.G. (author), McKee, R.H. (author), Owen, D.E. (author), Kulig, B.M. (author), TNO Kwaliteit van Leven (author)The neurobehavioral effects of inhaled cyclohexane in rats and humans are investigated to define relationships between internal doses and acute central nervous system effects. Rats are exposed for 3 consecutive days at target concentrations of 0, 1.4, 8, and 28 g/m3, 8 h/d. Measurements include standardized observational measures, spontaneous...article 2009
- document
-
Li, X. (author), Kjellander, B.K.C. (author), Anthony, J.E. (author), Bastiaansen, C.W.M. (author), Broer, D.J. (author), Gelinck, G.H. (author), TNO Industrie en Techniek (author)Here, a new approach is introduced to prepare large single crystals of π-conjugated organic molecules from solution. Utilizing the concept of azeotropism, single crystals of tri-isopropylsilylethynyl pentacene (TIPS-PEN) with dimensions up to millimeters are facilely self-assembled from homogeneous solutions comprising two solvents with opposing...article 2009
- document
-
Wierckx, N. (author), Ruijssenaars, H.J. (author), de Winde, J.H. (author), Schmid, A. (author), Blank, L.M. (author), TNO Kwaliteit van Leven (author)The physiological effects of genetic and transcriptional changes observed in a phenol producing mutant of the solvent-tolerant Pseudomonas putida S12 were assessed with metabolic flux analysis. The upregulation of a malate/lactate dehydrogenase encoding gene could be connected to a flux increase from malate to oxaloacetate. A mutation in the...article 2009
- document
-
TrgI, toluene repressed gene I, a novel gene involved in toluene-tolerance in Pseudomonas putida S12Volkers, R.J.M. (author), Ballerstedt, H. (author), Ruijssenaars, H. (author), de Bont, J.A.M. (author), de Winde, J.H. (author), Wery, J. (author), TNO Kwaliteit van Leven (author)Pseudomonas putida S12 is well known for its remarkable solvent tolerance. Transcriptomics analysis of this bacterium grown in toluene-containing chemostats revealed the differential expression of 253 genes. As expected, the genes encoding one of the major solvent tolerance mechanisms, the solvent efflux pump SrpABC and its regulatory genes...article 2009
- document
-
TNO Kwaliteit van Leven (author), Verhoef, S. (author), Wierckx, N. (author), Westerhof, R.G.M. (author), Winde, J.H.de (author), Ruijssenaars, H.J. (author)Two solvent-tolerant Pseudomonas putida S12 strains, originally designed for phenol and p-coumarate production, were engineered for efficient production of p-hydroxystyrene from glucose. This was established by introduction of the genes pal and pdc encoding L-phenylalanine/L-tyrosine ammonia lyase and p-coumaric acid decarboxylase, respectively....article 2009
- document
-
Abu-Zahra, M.R.M. (author), Feron, P.H.M. (author), Jansens, P.J. (author), Goetheer, E.L.V. (author), TNO Industrie en Techniek (author)This work describes a study in advanced post-combustion based on CO2-capture technologies to be integrated within the Hypogyny concept (electricity generation with co-hydrogen production). Two different Hypogen concepts based on integrating IGCC (Integrated Gasification Combined Cycle) and post-combusting CO2 capture are proposed and...article 2009
- document
-
Peter, M. (author), Furthner, F. (author), Deen, J. (author), de Laat, W.J.M. (author), Meinders, E.R. (author), TNO Industrie en Techniek (author)In this paper the challenges of patterning electrodes with separations in the micron and sub-micron range onto thin polyethylene naphthalate foils for use in biochips are discussed. It was found that it was necessary to improve the adhesion of the metal electrodes to the foil by using plasma treatment and/or an adhesion layer, and a quantitative...article 2009
- document
-
Kudryashova, E.V. (author), de Jongh, H.H.J. (author), TNO Kwaliteit van Leven (author), KvL (author)The possibility of modulating the mesoscopic properties of food colloidal systems by the dielectric constant is studied by determining the impact of small amounts of ethanol (10%) on the adsorption of egg white ovalbumin onto the air-water interface in the absence and presence of pectin. The adsorption kinetics was monitored using tensiometry....article 2008
- document
-
van den Berg, C. (author), Roelands, C.P.M. (author), Bussmann, P.J.Th. (author), Goetheer, E.L.V. (author), Verdoes, D. (author), van der Wielen, L. (author), TNO Kwaliteit van Leven TNO Separation Technolog (author)The application of extractants in whole-cell biocatalysis can have a positive impact on industrial fermentations, in terms of productivity, total amount of product produced, and cell growth. When a product is continuously removed from the microorganism surroundings, product inhibition will be diminished. The strategy is exemplified using phenol...article 2008
- document
-
Burghoff, B. (author), Goetheer, E.L.V. (author), de Haan, A.B. (author), TNO Industrie en Techniek (author)The focus of this investigation is the development of a solvent impregnated resin for phenol removal from dilute aqueous solutions. Using a solvent impregnated resin (SIR) eliminates the problem of emulsification encountered in liquid-liquid extraction. Impregnated MPP particles and impregnated XAD16 particles are successfully used for phenol...article 2008