Richtlijnen Jeugdgezondheidszorgrichtlijn 'Huidafwijkingen' [Youth Healthcare guideline Skin disorders]

There is a high incidence of skin disorders; these are also frequently encountered within Youth Healthcare (YHC). Some skin disorders are caused by an underlying disease, syndrome or child abuse. Therefore, detection of these causes in an early stage is important. Skin disorders can have a huge psychosocial impact on both child and parents. This...

Confirmation of synthetic glucocorticoids with liquid chromatography/mass spectrometry: Organization and results of an international interlaboratory comparison test

Within the framework of a European Union (EU) research project entitled "Food Safety Screening: Synthetic Glucocorticoids (QLK1-1999-00122)," an international interlaboratory ring test was organized to compare and evaluate different liquid chromatography/mass spectrometry (LC/MS) confirmatory methods that are applied in European monitoring...

Dermal Exposure to Chemicals

Chemicals / CAS: 4,4' methylenedianiline, 101-77-9; Hazardous Substances.

Variability of Task-based Dermal Exposure Measurements from a Variety of Workplaces

Introduction: The RISKOFDERM project collected task-based estimates of potential dermal exposure from a wide range of industries and services from around Europe. A formal statistical analysis was carried out to explore the main components of variability in dermal exposure levels. The central research question was to what extent dermal exposure...

Human skin condition and its associations with nutrient concentrations in serum and diet

Background: Nutritional factors exert promising actions on the skin, but only scant information is available on the modulating effects of physiologic concentrations of nutrients on the skin condition of humans. Objective: The objective was to evaluate whether nutrient concentrations in serum and diet are associated with the skin condition of...

A relation between blood pressure and stiffness of joints and skin

Background. Blood pressure, particularly pulse pressure, is associated with arterial wall stiffness, but little is known about its relation to stiffness of other parts of the body. We examined the extent to which blood pressure levels in young healthy children are related to stiffness of various tissues. Methods. In November 2000, we studied 95...

The RISKOFDERM project: T2 - RISKOFDERM - Europas Beschäftigte sollen nicht länger ihre Haut zu Markte tragen

Reducing dermal exposure to chemicals is a challenging task for occupational safety and health. In the European RISKOFDERM project 15 institutes in ten member states gather dermal exposure information and measurement data in relation to various tasks. First results are available. Based on this information i) a predictive model for estimating...

Nutritional skin care: Health effects of micronutrients and fatty acids

Human skin is continuously exposed to internal and external influences that may alter its condition and functioning. As a consequence, the skin may undergo alterations leading to photoaging, inflammation, immune dysfunction, imbalanced epidermal homeostasis, or other skin disorders. Modern nutritional science is developing new insights into the...

Low doses of UVB or UVA induce chromosomal aberrations in cultured human skin cells

Chromosomal defects are frequently present in malignant and premalignant skin disorders; however, it is not known whether ultraviolet radiation from sunlight plays a role in their induction. To obtain information on the ability of ultraviolet A and ultraviolet B to induce chromosomal aberrations, cultured melanocytes and fibroblasts were exposed...

Pathogenicity of Peptostreptococcus micros morphotypes and Prevotella species in pure and mixed culture

Recently, an atypical rough colony morphotype of Peptostreptococcus micros, a species which is found in ulcerating infections, including periodontitis, was isolated. The virulence of morphotypes alone and in combination with Prevotella intermedia and P. nigrescens was investigated both in vivo and in vitro. All strains tested induced abscesses...

Skin and liver diseases induced in flounder (Platichthys flesus) after longterm exposure to contaminated sediments in large-scale mesocosms

Chemicals/CAS: Metals; Polychlorinated Biphenyls; Water Pollutants

Risk assessment of dermal exposure of greenhouse workers to pesticides after re-entry

On 18 farms for rose culture in greenhouses in The Netherlands, dermal exposure of hands and forearms to abamectin (avermectin B1), dodemorph (4- cyclododecyl-2,6-dimethylmorpholinium acetate) and bupirimate (5-butyl-2- (ethylamino)-6-methyl-4-pyrimidinyl dimethylsulphate) was measured during crop activities. Dermal exposure during cutting (75...