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Nader, F.H. (author), van Unen, M. (author), Darnault, R. (author), Rudkiewicz, J.-L. (author), Matenco, L. (author)The thermal evolution of collisional orogens is largely controlled by their kinematic and burial/exhumation history, where sedimentation and erosion rates, as well as shear heating and deep heat flow supply conditions for the temperature distribution, fluid flow and the associated fluid-rock interactions. The aim of our research is to understand...article 2023
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Weda, J. (author), Erp, J.V. (author), Mader, A. (author)The actuation speed of a pressure stimulus may influence its perception threshold. This is relevant for the design of haptic actuators and haptic interaction. We ran a study using a motorized ribbon to apply pressure stimuli (squeezes) to the arm at three different actuation speeds and used the PSI method to find the perception threshold for 21...article 2023
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van Mierlo, M.M.F. (author), Pardo, L.M. (author), Fieten, K.B. (author), van den Broek, T.J. (author), Schuren, F.H.J. (author), van Geel, M. (author), Pasmans, S.G.M.A. (author)Background: Interactions between the skin barrier, immune system, and microbiome underlie the development of atopic dermatitis (AD). Objective: To investigate the skin and nasal microbiome in relation to filaggrin gene (FLG) mutations. Methods: A cross-sectional study including 77 children with difficult-to-treat AD. The entire encoding region...article 2022
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Heus, R. (author), van Berlo, M.P.W. (author), van Berlo, B.M.A. (author), Mol, D. (author), Daanen, H.A.M. (author), Kuklane, K. (author)During the early stage of a fire, a process operator often acts as the first responder and may be exposed to high heat radiation levels. The present limit values of long- (>15 min) and short-term exposure (article 2022
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McNally, K. (author), Goede, H.A. (author), Schinkel, J. (author), Gorce, J.P. (author), Warren, N. (author)The dermal Advanced REACH Tool (dART) is a tier 2 exposure model for estimating dermal exposure to the hands (mg min-1) for non-volatile liquid and solid-in-liquid products. The dART builds upon the existing ART framework and describes three mass transport processes (deposition (Dhands), direct emission and direct contact (Ehands), and contact...article 2022
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Neural representations of haptic object size in the human brain revealed by multivoxel fMRI patternsPerini, F. (author), Powell, T. (author), Watt, S.J. (author), Downing, P.E. (author)The brain must interpret sensory input from diverse receptor systems to estimate object properties. Much has been learned about the brain mechanisms behind these processes in vision, but our understanding of haptic perception remains less clear. Here we examined haptic judgments of object size, which require integrating multiple cutaneous and...article 2020
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van Lier, H.G. (author), Pieterse, M.E. (author), Garde, A. (author), Postel, M.G. (author), de Haan, H.A. (author), Vollenbroek-Hutten, M.M.R. (author), Schraagen, J.M.C. (author), Noordzij, M.L. (author)Wearable physiological measurement devices for ambulatory research with novel sensing technology are introduced with ever increasing frequency, requiring fast, standardized, and rigorous validation of the physiological signals measured by these devices and their derived parameters. At present, there is a lack of consensus on a standardized...article 2020
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Žemaitis, A. (author), Mikšys, J. (author), Gaidys, M. (author), Gecys, P. (author), Gedvilas, M. (author)Bio-inspired surfaces are able to decrease friction with fluids and gases. The most recognizable are shark-skin-like riblet surface structures. Such bio-inspired surfaces can be formed by the laser ablation technique. In this work, bio-inspired riblet surfaces with grooves were formed using picosecond ultraviolet laser ablation on pre-heated...article 2019
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Goede, H.A. (author), McNally, K. (author), Gorce, J.P. (author), Marquart, H. (author), Warren, N.D. (author), Fransman, W. (author), Tischer, M. (author), Schinkel, J. (author)This article describes the development of a mechanistic model for underpinning the dermal Advanced REACH Tool (dART), an extension of the existing ART model and its software platform. It was developed for hand exposure to low volatile liquids (vapour pressure ≤ 10 Pa at 20°C) including solids-in-liquid products. The model is based on an existing...article 2019
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Vesela, S. (author), Kingma, B.R.M. (author), Frijns, A.J.H. (author), van Marken Lichtenbelt, W.D. (author)The quality of local skin temperature prediction by thermophysiological models depends on the local skin blood flow (SBF) control functions. These equations were derived for low activity levels (0.8-1 met ) and mostly in sitting or supine position. This study validates and discusses the prediction of foot SBF during activities of 1-3 met in male...article 2019
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Visser, L. (author), Kingma, B.R.M. (author), Willems, E. (author), Loomans, M. (author), Schellen, H. (author), Broers, W. (author), op 't Veld, P. (author), van Marken Lichtenbelt, W. (author)Studies indicate that the energy performance gap between real and calculated energy use can be explained for 80% by occupant behaviour. This human factor may be composed of routine and thermoregulatory behaviour. When occupants do not feel comfortable due to high or low operative temperatures and resulting high or low skin temperatures, they are...conference paper 2019
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McNally, K. (author), Gorce, J.P. (author), Goede, H.A. (author), Schinkel, J. (author), Warren, N. (author)The dermal Advanced REACH Tool (dART) is a Tier 2 exposure modelling tool currently in development for estimating dermal exposure to the hands (mg min-1) for non-volatile liquid and solids-in-liquid products. The dART builds upon the existing ART framework and describes three mass transport processes [deposition (Dhands), direct emission and...article 2019
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Brouwer, A.M. (author), Stuldreher, I.V. (author), Thammasan, N. (author)Monitoring directed auditory attention in groups can be helpful in a range of contexts. Concurrent change in physiological variables across multiple listeners (physiological synchrony – PS) may be a suitable marker of attentional focus as caused by shared affective or cognitive processes. We here determine PS for EEG (electroencephalography),...conference paper 2019
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Rosa, N. (author), Veltkamp, R.C. (author), Hurst, W. (author), Nijboer, T. (author), Gilbers, C. (author), Werkhoven, P. (author)The classic rubber hand illusion (RHI) experiment studies the sense of embodiment over a fake limb. Distinguished subcomponents of embodiment are ownership (sense of self-attribution of a body), agency (sense of having motor control), and self-location (the spatial experience of being inside a body), and are typically evoked in either reality or...article 2019
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Brouwer, A.M. (author), van Beurden, M.H.P.H. (author), Nijboer, L. (author), Derikx, L. (author), Binsch, O. (author), Gjaltema, C. (author), Noordzij, M. (author)We investigated electrodermal activity (EDA) in 130 participants undergoing a shortened version of a novel easy, effective and controlled method to induce stress (the Sing-a-Song Stress Test). We compared skin conductance level (SCL), amplitude and number of skin conductance response peaks with respect to their sensitivity to the known stressor,...bookPart 2018
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- Brouwer, A.M. (author), van Beurden, M. (author), Nijboer, L. (author), Derikx, L. (author), Binsch, O. (author), Gjaltema, C. (author), Noordzij, M. (author) conference paper 2018
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de Ligt, R. (author), van Duijn, E. (author), Grossouw, D. (author), Bosgra, S. (author), Burggraaf, J. (author), Windhorst, A. (author), Peeters, P.A.M. (author), van der Luijt, G.A. (author), Alexander-White, C. (author), Vaes, W.H.J. (author)A clinical pharmacokinetic study was performed in 12 healthy women to evaluate systemic exposure to aluminum following topical application of a representative antiperspirant formulation under real-life use conditions. A simple roll-on formulation containing an extremely rare isotope of aluminum (26 Al) chlorohydrate (ACH) was prepared to...article 2018
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Reisinger, K. (author), Blatz, V. (author), Brinkmann, J. (author), Downs, T.R. (author), Fischer, A. (author), Henkler, F. (author), Hoffmann, S. (author), Krul, C. (author), Liebsch, M. (author), Luch, A. (author), Pirow, R. (author), Reus, A.A. (author), Schulz, M. (author), Pfuhler, S. (author)Recently revised OECD Testing Guidelines highlight the importance of considering the first site-of-contact when investigating the genotoxic hazard. Thus far, only in vivo approaches are available to address the dermal route of exposure. The 3D Skin Comet and Reconstructed Skin Micronucleus (RSMN) assays intend to close this gap in the in vitro...article 2018
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Goede, H. (author), de Vries, Y.C. (author), Kuijpers, E. (author), Fransman, W. (author)This review describes an evaluation of the effectiveness of Risk Management Measures (RMM) for nanomaterials in the workplace. Our aim was to review the effectiveness of workplace RMM for nanomaterials and to determine whether established effectiveness values of conventional chemical substances applied for modelling purposes should be adopted or...article 2018
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Masthoff, L.J.N. (author), Blom, W.M. (author), Rubingh, C.M. (author), Klemans, R.J.B. (author), Remington, B.C. (author), Bruijnzeel-Koomen, C.A.F.M. (author), van Hoffen, E. (author), Houben, G.F. (author), Meyer, Y. (author), Pasmans, S.G.M.A. (author), Knulst, A.C. (author)[No abstract available] Chemicals / CAS immunoglobulin E, 37341-29-0; Allergens; Antigens, Plant; Cor a 14 allergen, hazelnut; Cor a 9 protein, hazelnut; Immunoglobulin E; Plant Proteins.article 2018