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van Damme, I.M. (author), Mestres-Fitó, P. (author), Ramaker, H.J. (author), Hulsbergen, A.W.C. (author), van der Heijden, A.E.D.M. (author), Kranenburg, R.F. (author), van Asten, A.C. (author)There is an ongoing forensic and security need for rapid, on-scene, easy-to-use, non-invasive chemical identification of intact energetic materials at pre-explosion crime scenes. Recent technological advances in instrument miniaturization, wireless transfer and cloud storage of digital data, and multivariate data analysis have created new and...article 2023
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Albers, N. (author), Neerincx, M.A. (author), Aretz, N.L. (author), Ali, M. (author), Ekinci, A. (author), Brinkman, W.P. (author)Virtual coaches have the potential to address the low adherence common to eHealth applications for behavior change by, for example, providing motivational support. However, given the multitude of factors affecting users’ attitudes toward virtual coaches, more insights are needed on how such virtual coaches can be designed to affect these...conference paper 2023
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Hendriks, T. (author), Akesson, B. (author), Voeten, J. (author), Hendriks, M. (author), Coronel Parada, J. (author), Garcia-Gordillo, M. (author), Saez, S. (author), Valls, J.J. (author)Market trends show advanced usage of safetycritical systems with novel services based on smart data analytics. Customers require continuous updates to applications and services and seek lower costs, and easy-to-install solutions (maintenance) for safety-critical cyber-physical systems (CPS). Leveraging edge and cloud technologies has the...conference paper 2023
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Fokkink, W.J. (author), Goorden, M.A. (author), Hendriks, D. (author), van Beek, D.A. (author), Hofkamp, A.T. (author), Reijnen, F.F.H. (author), Etman, L.F.P. (author), Moormann, L. (author), van de Mortel-Fronczak, J.M. (author), Reniers, M.A. (author), Rooda, J.E. (author), van der Sanden, L.J. (author), Schiffelers, R.R.H. (author), Thuijsman, S.B. (author), Verbakel, J.J. (author), Vogel, J.A. (author)The Eclipse Supervisory Control Engineering Toolkit (ESCETTM) is an open-source project to provide a model-based approach and toolkit for developing supervisory controllers , targeting their entire engineering process. It supports synthesis-based engineering of supervisory controllers for discrete-event systems, combining model-based engineering...conference paper 2023
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Tolksdorf, L. (author), Tejeda, A. (author), van de Wouw, N. (author), Birkner, C. (author)In automated driving, risk describes potential harm to passengers of an autonomous vehicle (AV) and other road users. Recent studies suggest that human-like driving behavior emerges from embedding risk in AV motion planning algorithms. Additionally, providing evidence that risk is minimized during the AV operation is essential to vehicle safety...conference paper 2023
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van der Ploeg, C. (author), Braat, M. (author), Masini, B. (author), Brouwer, J. (author), Paardekoper, J.P. (author)The introduction of highly automated vehicles on the public road may improve safety and comfort, although its success will depend on social acceptance. This requires trajectory planning methods that provide safe, proactive, and comfortable trajectories that are risk-averse, take into account predictions of other road users, and comply with...conference paper 2023
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Morgan, A.S. (author), Zeitlin, J. (author), Källén, K. (author), Draper, E.S. (author), Maršál, K. (author), Norman, M. (author), Serenius, F. (author), van Buuren, S. (author), Johnson, S. (author), Benhammou, V. (author), Pierrat, V. (author), Kaminski, M. (author), Foix L'Helias, L. (author), Ancel, P.Y. (author), Marlow, N. (author)Aim: We investigated the timing of survival differences and effects on morbidity for foetuses alive at maternal admission to hospital delivered at 22 to 26 weeks’ gestational age (GA). Methods: Data from the EXPRESS (Sweden, 2004–07), EPICure-2 (England, 2006) and EPIPAGE-2 (France, 2011) cohorts were harmonised. Survival, stratified by GA, was...article 2022
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Dhondt, S. (author), Kraan, K.O. (author), Bal, M. (author)The impact of technological change on the content of jobs and accompanying skills is a central topic across disciplines. To date, ample research has directly linked the technological change to shifts in skills use; however, organisational change is rarely considered as an influencing factor. Based on a panel survey, this paper uses a Luhmannian...article 2022
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Olga, L. (author), Bobeldijk-Pastorova, I. (author), Bas R.C., (author), Seidel, F. (author), Snowden, S.G. (author), Furse, S. (author), Ong, K.K. (author), Kleemann, R. (author), Koulman, A. (author)This protocol outlines a translational lipidomic approach to discover lipid biomarkers that could predict morphometric body and histological organ measurements (e.g., weight and adiposity gains) during specific stages of life (e.g., early life). We describe procedures ranging from animal experimentation and histological analyses to downstream...article 2022
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Kunneman, Y. (author), Alves da Motta-Filho, M. (author), de Waa, J (author)To support effective and successful projects, Service Design practitioners rely on insights that mainly build on qualitative research methodology. The literature on data science promises to help transform how design research is done, adding sophisticated quantitative analyses, complementing existing methods with the power of machines. Due to...article 2022
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- Houtman, I.L.D. (author) public lecture 2022
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Schlüter, U. (author), Meyer, J. (author), Ahrens, A. (author), Borghi, F. (author), Clerc, F. (author), Delmaar, C. (author), Di Guardo, A. (author), Dudzina, T. (author), Fantke, P. (author), Fransman, W. (author), Hahn, S. (author), Heussen, H. (author), Jung, C. (author), Koivisto, J. (author), Koppisch, D. (author), Paini, A. (author), Savic, N. (author), Spinazzè, A. (author), Jeddi, M.Z. (author), von Goetz, N. (author)Exposure models are essential in almost all relevant contexts for exposure science. To address the numerous challenges and gaps that exist, exposure modelling is one of the priority areas of the European Exposure Science Strategy developed by the European Chapter of the International Society of Exposure Science (ISES Europe). A strategy was...article 2022
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Georgieva, I.N. (author), Lazo, C.B. (author), Timan, T. (author), van Veenstra, A.F.E. (author)In the field of AI ethics, after the introduction of ethical frameworks and the evaluation thereof, we seem to have arrived at a third wave in which the operationalisation of ethics is central. Operationalisation is required, since ethics frameworks are often not suited to be used by data scientists in the development of AI-based services or...article 2022
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van der Ploeg, C.P.B. (author), Oomen, P. (author), van Lent, M. (author)De Prenatale Screening Infectieziekten en Erytrocyten-immunisatie (PSIE) is een landelijk bevolkingsonderzoek waarbij een zwangere vrouw in het eerste verloskundige consult een bloedonderzoek aangeboden krijgt. Het bloed wordt gescreend op hepatitis B (hepB), syfilis, HIV, Rhesus (D)-antigeen (RhD), irregulaire erytrocyten antistoffen (IEA) en...report 2022
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Schlunk, F. (author), Fisher, P. (author), Princen, H.M.G. (author), Rex, A. (author), Prinz, V. (author), Foddis, M. (author), Lütjohann, D. (author), Laufs, U. (author), Endres, M. (author)Monoclonal anti-proprotein convertase subtilisin/kexin type 9 (PSCK9) neutralizing antibodies effectively lower plasma cholesterol levels and decrease cardiovascular events but also raised some concern that cognitive function could worsen as a side effect. Here, we performed experiments in mice to characterize the effect of anti-PCSK9 antibodies...article 2021
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Rijnders, M. (author), Jans, S (author), Groesen, K. (author)Reduced antenatal care services and an acute halt to Centeringbased antenatal group care were one of the results of the COVID-19 lockdown in the Netherlands. The pandemic and the subsequent reduction in antenatal services gave rise to anxiety and stress in pregnant women, increasing the need for group antenatal care more than ever. Throughout...article 2021
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- Duijster, D. (author), Vermaire, E.J.H. (author) bookPart 2021
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Goemans, B.F. (author), Noort, S. (author), Blink, M. (author), Wang, Y.D. (author), Peters, S.T.C.J. (author), van Wouwe, J.P. (author), Kaspers, G. (author), de Haas, V. (author), Kollen, W.J. (author), van der Velden, V.H.J. (author), Gruber, T.A. (author), Zwaan, C.M. (author)The aim of this study was to define a population-based frequency of TAM in DS newborns. The Dutch Pediatric Surveillance Unit (DPSU) registers newborns with DS and TAM screening was added to this registration from Jan 1, 2008, until Jan 1, 2013 (Erasmus MC MEC-2007-168, Netherlands Trial Register NL1587). Based on the live birth prevalence of DS...article 2021
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Vermaire, J.H. (author), Kalf, S.M. (author), Schuller, A.A. (author)Background. People with intellectual disabilities have worse health outcomes compared to their peers without. However, regarding oral health parameters, recent systematic reviews reported conflicting evidence. The aim was to assess whether adolescents with MBID differ from their peers in oral health and oral health behaviour. Methods. Ninety...article 2021
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- Burdorf, A. (author), Pronk, A. (author), Peters, S. (author), Oude Hengel, K. (author), Stokholm, Z. (author), Kolstad, H. (author), Schlunssen, V. (author), van Veldhoven, K. (author), Basinas, I. (author), van Tongeren, M. (author) public lecture 2021