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Peters, S.L.A. (author), Tabasi, A. (author), Kingma, I. (author), van Dijk, W. (author), van Dieën, J.H. (author)Mechanical loading of the low-back is an important risk factor for the development of low-back pain. Real-time estimation of the L5S1 joint moment (ML5S1) can give an insight to reduce mechanical loading. Model accuracy depends on sensor information, limiting the number of input variables to estimate ML5S1 increases practical feasibility, but...article 2023
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Bonde, J.P.E. (author), Sell, L. (author), Flachs, E.M. (author), Coggon, D. (author), Albin, M. (author), Oude Hengel, K.M. (author), Kolstad, H. (author), Mehlum, I.S. (author), Schlünssen, V. (author), Solovieva, S. (author), Torén, K. (author), Jakobsson, K. (author), Nielsen, C. (author), Nilsson, K. (author), Rylander, L. (author), Petersen, K.U. (author), Tøttenborg, S.S. (author)Objective: Mounting evidence indicates increased risk of COVID-19 among healthcare personnel, but the evidence on risks in other occupations is limited. In this study, we quantify the occupational risk of COVID-19-related hospital admission in Denmark during 2020-2021. Methods: The source population included 2.4 million employees age 20-69 years...article 2023
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Bajard, L. (author), Adamovsky, O. (author), Audouze, K. (author), Baken, K. (author), Barouki, R. (author), Beltman, J. (author), Beronius, A. (author), Bonefeld-Jørgensen, E.C. (author), Cano-Sancho, G. (author), de Baat, M.L. (author), Di Tillio, F. (author), Fernández, M.F. (author), FitzGerald, R.E. (author), Gundacker, C. (author), Hernández, A.F. (author), Hilscherova, K. (author), Karakitsios, S. (author), Kuchovska, E. (author), Long, M. (author), Luijten, M. (author), Majid, S. (author), Marx-Stoelting, P. (author), Mustieles, V. (author), Negi, C.K. (author), Sarigiannis, D. (author), Scholz, S. (author), Sovadinova, I. (author), Stierum, R. (author), Tanabe, S. (author), Tollefsen, K.E. (author), van den Brand, A.D. (author), Vogs, C. (author), Wielsøe, M. (author), Wittwehr, C. (author), Blaha, L. (author)While human regulatory risk assessment (RA) still largely relies on animal studies, new approach methodologies (NAMs) based on in vitro, in silico or non-mammalian alternative models are increasingly used to evaluate chemical hazards. Moreover, human epidemiological studies with biomarkers of effect (BoE) also play an invaluable role in...article 2023
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Fransman, W. (author), Otten, W. (author), Marquart, H. (author), Preuhs, K. (author), Willemsen, J. (author), Boumann, H. (author), Gerritsen, R. (author)Objectives: Within the chemical legislation, REACH was implemented in order to improve safe working conditions with hazardous substances. Literature and real-life experiences by those concerned have shown that there are still gaps with a need for improved risk communication. This study elaborated on how information provided by REACH is...article 2023
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Santonen, T. (author), Mahiout, S. (author), Alvito, P. (author), Apel, P. (author), Bessems, J. (author), Bil, W. (author), Borges, T. (author), Bose-O'Reilly, S. (author), Buekers, J. (author), Canas Portilla, A.I. (author), Calvo, A.C. (author), de Alba González, M. (author), Dominguez-Morueco, N. (author), Lopez, M.E. (author), Falnoga, I. (author), Gerofke, A. (author), Caballero, M.D.C.G. (author), Horvat, M. (author), Huuskonen, P. (author), Kadikis, N. (author), Kolossa-Gehring, M. (author), Lange, R. (author), Louro, H. (author), Martins, C. (author), Meslin, M. (author), Niemann, L. (author), Diaz, S.P. (author), Plichta, V. (author), Porras, S.P. (author), Rousselle, C. (author), Scholten, B. (author), Silva, M.J. (author), Šlejkovec, Z. (author), Tratnik, J.S. (author), Joksic, A.Š. (author), Tarazona, J.V. (author), Uhl, M. (author), van Nieuwenhuyse, A. (author), Viegas, S. (author), Vinggaard, A.M. (author), Woutersen, M. (author), Schoeters, G. (author)One of the aims of the European Human Biomonitoring Initiative, HBM4EU, was to provide examples of and good practices for the effective use of human biomonitoring (HBM) data in human health risk assessment (RA). The need for such information is pressing, as previous research has indicated that regulatory risk assessors generally lack knowledge...article 2023
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van Kampen, J. (author), Lammers, M. (author), Steijn, W. (author), Guldenmund, F. (author), Groeneweg, J. (author)In the Netherlands, approximately 2.300 workers have a serious reportable accident at work every year, of which around 60 are fatal (Inspectie SZW, 2020; Bellamy et al., 2014). Safety practitioners employ many methods to improve occupational safety for workers within their companies. Interventions might, for example, be aimed at improving...article 2023
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Crul, M. (author), Breukels, O. (author), Ng, S. (author), le Feber, M. (author), Kuijpers, E. (author), Smeets, O. (author)Objective. Some drugs need processing before they can be administered or dispensed. We measured airborne exposure of pharmacy staff to small particles when performing these tasks. Methods. Reconstitution of powdered drugs in vials; crushing, splitting, and counting of tablets; and opening of capsules, using different ventilation strategies, were...article 2023
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Shandilya, N. (author), Barreau, M.S. (author), Suarez-Merino, B. (author), Porcari, A. (author), Pimponi, D. (author), Alstrup Jensen, K. (author), Fransman, W. (author), Franken, R. (author)There has been an increasing use of advanced materials, particularly manufactured nanomaterials, in industrial applications and consumer products in the last two decades. It has instigated concerns about the sustainability, in particular, risks and uncertainties regarding the interactions of the manufactured nanomaterials with humans and the...article 2023
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Eekhout, I. (author), van Tongeren, M. (author), Pearce, N. (author), Oude Hengel, K.M. (author)Objective This study aimed to investigate the effects of occupational exposures on the risk of a positive COVID-19 test, and whether this differed across pandemic waves. Methods Data from 207 034 workers from The Netherlands with test data on COVID-19 from June 2020 until August 2021 were available. Occupational exposure was estimated by using...article 2023
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Giraldo, J.S. (author), Bañol Arias, N. (author), Vergara, P.P. (author), Vlasiou, M. (author), Hoogsteen, G. (author), Hurink, J.L. (author)This paper introduces a AC stochastic optimal power flow (SOPF) for the flexibility management of electric vehicle (EV) charging pools in distribution networks under uncertainty. The AC SOPF considers discrete utility functions from charging pools as a compensation mechanism for eventual energy not served to their charging tasks. An application...article 2023
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McQueen, A.D. (author), Suedel, B.C. (author), Ferguson, M.W. (author), de Jong, C.A.F. (author), Thomsen, F. (author)Underwater sounds produced from anthropogenic sources may pose risks to aquatic life, yet there is much uncertainty regarding the prediction of these impacts. A structured risk-based framework for identifying, assessing, and man aging risks associated with underwater sounds has been previously proposed; however, real-world applications of the...bookPart 2023
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Begtrup, L.M. (author), Bonde, J.P.E. (author), Coggon, D. (author), Jensen, J.H. (author), Meulengracht Flachs, E. (author), Schlünssen, V. (author), Kolstad, H.A. (author), Albin, M. (author), Oude Hengel, K.M. (author), Sivesind Mehlum, I. (author), Solovieva, S. (author), Torén, K. (author), Jakobsson, K. (author), Nielsen, C. (author), Nilsson, K. (author), Rylander, L. (author), Vilhelmsson, A. (author), Petersen, K.U. (author), Tøttenborg, S.S. (author)Objective To map the risk of work-related SARS-CoV-2 across occupations and pandemic waves and investigate its impact on morbidity and partner-risk. Methods The cohort includes 2,4 million employees aged 20–69 with follow-up from 2020 through 2021. During this period, 261,203 employees had a positive SARS-CoV-2 test and 4416 were admitted to...article 2023
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Verstraten, P. (author), van der Weijde, A.H. (author)Purpose of Review: This paper argues that, for the purpose of determining business cases for renewable energy assets, simple simulation methods can be very valuable. We demonstrate this through the application of a stochastic agent-based energy market model which, instead of a modelling the explicit drivers behind future investments, treats...article 2023
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Strauss, A. (author), Bergmeister, K. (author), Daro, P. (author), Mancini, G. (author), Sattler, F. (author), Bigaj-van Vliet, A.J. (author)Accurate information from monitoring of structures plays a critical role in making informed decisions regarding structural safety control and maintenance needs. Unfortunately, there are several gaps in the existing standards and the monitoring practices at local, national, and transnational (e.g., European) levels. The wide diversity of assets...article 2023
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Wessels, M. (author)Law enforcement agencies increasingly adopt algorithms for their policing practices, leading to new accountability challenges. However, academic literature tends to regard algorithmic applications as a single entity, resulting in broad and general statements on these risks. By introducing a sociotechnical model of algorithmic policing, this...article 2023
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Blom, W.M. (author), Westerhout, J. (author), Houben, G.F. (author)Lack of guidance regarding selection of food intake values for allergen risk assessment can lead to different outcomes for similar levels of allergens in food products. Several food consumption survey databases (United States, North-West Europe, and Netherlands) were analyzed to identify optimal food intake percentiles using a sensitivity...article 2023
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Faber, A.H. (author), Brunner, A.M. (author), Schimmel, M. (author), Schot, P.P. (author), de Voogt, P. (author), van Wezel, A. (author)Environmental risk assessment is generally based on atmospheric conditions for the modelling of chemical fate after entering the environment. However, during hydraulic fracturing, chemicals may be released deep underground. This study therefore focuses on the effects of high pressure and high temperature conditions on chemicals in flowback water...article 2023
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den Camp, O.O. (author), de Gelder, E. (author), Broos, J. (author)To ensure the safe and responsible deployment of vehicles equipped with Automated Driving Systems (ADSs) onto the public road, a safety assessment of such vehicles should be passed successfully. The assessment results should be unambiguous, easily understood by experts in the field, and explainable to authorities and the general public. An...conference paper 2023
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van Hartingsveldt, W. (author), Meijerink, M. (author)New or modified proteins will play a key role in innovation of food products and in improving the sustainability of our food supply chain. New or modified protein-containing food products and ingredients may however lead to novel allergen risks. At TNO, we support you in the assessment of such risks based on our long-standing expertise and...other 2023
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van Hartingsveldt, W. (author), Houben, G.F. (author)Food products need to be safe! Allergen risk assessment is a key element of food safety assessment. Food allergic reactions as well as the risks thereof are a major burden to the food allergic consumer and their families as well as to the healthcare system.other 2023