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Krone, T. (author), Boessen, R. (author), Bijlsma, S. (author), van Stokkum, R. (author), Clabbers, N.D.S. (author), Pasman, W.J. (author)Background. N-of-1 designs gain popularity in nutritional research because of the improving technological possibilities, practical applicability and promise of increased accuracy and sensitivity, especially in the field of personalized nutrition. This move asks for a search of applicable statistical methods. Objective. To demonstrate the...article 2020
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Pasma, W. (author), Wesselink, E.M. (author), van Buuren, S. (author), de Graaff, J.C. (author), van Klei, W.A. (author)Physiologic data from anesthesia monitors are automatically captured. Yet erroneous data are stored in the process as well. While this is not interfering with clinical care, research can be affected. Researchers should find ways to remove artifacts. The aim of the present study was to compare different artifact annotation strategies, and to...article 2020
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Zwamborn, A.P.M. (author), Theil, A. (author)In this report (written in the Dutch language) a non-ionizing radiation hazards analysis has been conducted for the SMART-L air-defense radar planned in Herwijnen, The Netherlands. The expected RF exposure is compared with the reference values from ICNIRP1998 as well as the recently published ICNIRP2020.report 2020
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van den Hoek, A.M. (author), Verschuren, L. (author), Worms, N. (author), van Nieuwkoop, A. (author), de Ruiter, C. (author), Attema, J. (author), Menke, A.L. (author), Caspers, M.P.M. (author), Radhakrishnan, S. (author), Salic, K. (author), Kleemann, R. (author)Non-alcoholic steatohepatitis (NASH) is a fast-growing liver disorder that is associated with an increased incidence of cardiovascular disease and type 2 diabetes. Animal models adequately mimicking this condition are scarce. We herein investigate whether Ldlr−/−. Leiden mice on different high-fat diets represent a suitable NASH model. Ldlr−/−....article 2020
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Yang, C. (author), Hawwash, D. (author), de Baets, B. (author), Bouwman, J. (author), Lachat, C. (author)Robust recommendations for healthy diets and nutrition require careful synthesis of available evidence. Given the increasing volume of research articles generated, the retrieval and synthesis of evidence are increasingly becoming laborious and time-consuming. Information technology could help to reduce workload for humans. To guide supervised...article 2020
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van der Stap, N. (author), Benoist, K. (author), Schutte, K. (author)This paper shows the Netherlands contribution to NATO SET-240 on Exploitation of Longwave Infrared Airborne Hyperspectral Data, that focusses on the detection of soil disturbances, buried objects, and nonburied (surface) objects. Together with other hyperspectral feasibility research on maritime target detection and machine learning. Hyperbolic...conference paper 2020
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Boehrer, N. (author), Gabriel, A. (author), Brandt, A. (author), Uijens, W.R. (author), Kampmeijer, L. (author), van der Stap, N. (author), Schutte, K. (author)With the latest advances in image sensor technology, cameras are able to generate video with tens of megapixels per frame. These high resolution videos streams offer great potential to be used in the surveillance domain. For ground based systems, gigapixel streams are already used with great effect as illustrated by the ICME 2019 crowd counting...conference paper 2020
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- Gerretsen, A. (author), Smelik, R.M. (author), Smith, N. (author), Ly Van, K. (author) conference paper 2020
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Veerman, H.E.T. (author), Schleijpen, H.M.A. (author), Brettschneider, S.A. (author), Amram, R. (author)The observable infrared signature of naval platforms is crucial in determining survivability and is therefore an important issue in warfare. Increased detectability in the EM spectrum leads to higher susceptibility against threats like sea skimming anti-ship missiles. The infrared platform signature is not a fixed quantity but a highly dynamic...conference paper 2020
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de Wit, J.J.M. (author), Gusland, D. (author), Trommel, R.P. (author)The use of drones grows rapidly, recreational and commercial use, as well as malicious use. Following the trend of increasing use, there is an increasing need for radar systems to detect, track and characterize drones. Drone characterization, i.e., extracting information about the payload and intent of a drone, is crucial for the effective...conference paper 2020
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Hardtner, C. (author), Kornemann, J. (author), Krebs, K. (author), Ehlert, C.A. (author), Jander, A. (author), Zou, J. (author), Christopher, (author), Starz, C. (author), Rauterberg, S. (author), Sharipova, D. (author), Dufner, B. (author), Hoppe, N. (author), Dederichs, T.S. (author), Willecke, F. (author), Stachon, p. (author), Heidt, T. (author), Wolf, D. (author), von zur Muhlen, C. (author), Madl, J. (author), Kohl, P. (author), Kaeser, R. (author), Boettler, T. (author), Pieterman, E.J. (author), Princen, H.M.G. (author), Ho-Tin-Noe, B. (author), Swirski, F.K. (author), Robbins, C.S. (author), Bode, C. (author), Zirlik, A. (author), Hilgendorf, I. (author)Statins induce plaque regression characterized by reduced macrophage content in humans, but the underlying mechanisms remain speculative. Studying the translational APOE*3-Leiden.CETP mouse model with a humanized lipoprotein metabolism, we find that systemic cholesterol lowering by oral atorvastatin or dietary restriction inhibits monocyte...article 2020
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Schlunk, F. (author), Fisher, P. (author), Princen, H.M.G. (author), Rex, A. (author), Prinz, V. (author), Foddis, M. (author), Lütjohann, D. (author), Laufs, U. (author), Endres, M. (author)Anti-PCSK9 (proprotein convertase subtilisin/kexin type 9) antibodies lower low-density lipoprotein cholesterol levels and significantly reduce cardiovascular end points.1 Safety concerns were raised as ultra-low levels of low-density lipoprotein cholesterol can be achieved. Low cholesterol levels are associated with an increased rate of...article 2020
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Steen, M. (author), Nauta, J. (author)We view Societal Engagement (SE) as a key element of Responsible Innovation (RI) and want to better understand the advantages and disadvantage of SE, both in theory and in practice. Moreover, we are interested in the role that Research and Technology Organizations (RTOs) might play in bridging the gap between fundamental research in academia and...article 2020
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- Meessen, W.R.M.J. (author) article 2020
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Tsiaousis, M. (author)This paper concerns the task of detecting and classifying human actions in video. The dominant paradigm for action detection is to learn spatio-temporal features using 2D or 3D Convolutional Networks. We argue that several actions are characterized by their context, such as relevant objects and actors present in the video. To this end, we...report 2020
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- Kerstholt, J.H. (author), Vos, P.M. (author), de Koning, L. (author) book 2020
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- Maathuis, C. (author) doctoral thesis 2020
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Huber, D. (author), Horne, G. (author), Kallfass, D. (author), Hodicky, J. (author), de Reus, N.M. (author)In this paper the concept and architecture of Data Farming Services (DFS) are presented. DFS is developed and implemented in NATO MSG-155 by a multi-national team. MSG-155 and DFS are based on the data farming basics codified in MSG-088 and the actionable decision support capability developed in MSG-124. The developed services are designed as a...conference paper 2019
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Boersma, A. (author), Wang, Y. (author), Bäumer, S.M.B. (author), Lucas, P. (author), Willekers, R.W. (author), Halpin, A. (author), Gomez Rivas, J. (author), Hendriks, N. (author), den Toonder, J. (author)Stimulated Emission Depletion (STED)lithography is generally recognized as a very promising tool to overcome the Abbe diffraction limit and manufacture 3D submicron features using a mask-less lithography step. It has been shown to be able to create 100 nm resolution, 10 nm feature size features in a polymer resin. However, STED is not widely...other 2019
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Bosman, L.C. (author), Roelen, C.A.M. (author), Twisk, J.W.R. (author), Eekhout, I. (author), Heymans, M.W. (author)Purpose The aim of this study was to develop prediction models to determine the risk of sick leave due to musculoskeletal disorders (MSD) in non-sick listed employees and to compare models for short-term (i.e., 3 months) and long-term (i.e., 12 months) predictions. Methods Cohort study including 49,158 Dutch employees who participated in...article 2019