Searched for: subject%3A%22Remission%22
(1 - 10 of 10)
document
de Hoogh, I.M. (author), Pasman, W.J. (author), Boorsma, A. (author), van Ommen, B. (author), Wopereis, S. (author)
A type 2 diabetes mellitus (T2DM) subtyping method that determines the T2DM phenotype based on an extended oral glucose tolerance test is proposed. It assigns participants to one of seven subtypes according to their β-cell function and the presence of hepatic and/or muscle insulin resistance. The effectiveness of this subtyping approach and...
article 2022
document
de Hoogh, I.M. (author), Oosterman, J.E. (author), Otten, W. (author), Krijger, A.M. (author), Berbée-Zadelaar, S. (author), Pasman, W.J. (author), van Ommen, B. (author), Pijl, H. (author), Wopereis, S. (author)
Although lifestyle interventions can lead to diabetes remission, it is unclear to what extent type 2 diabetes (T2D) remission alters or improves the underlying pathophysiology of the disease. Here, we assess the effects of a lifestyle intervention on T2D reversal or remission and the effects on the underlying pathology. In a Dutch primary care...
article 2021
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Kim, C. (author), Colborn, K. (author), van Buuren, S. (author), Loar, T. (author), Stevens-Lapsley, J.E. (author), Kittelson, A.J. (author)
The purpose of this study was to develop and test personalized predictions for functional recovery after Total Knee Arthroplasty (TKA) surgery, using a novel neighbors-based prediction approach. We used data from 397 patients with TKA to develop the prediction methodology and then tested the predictions in a temporally distinct sample of 202...
article 2021
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Pereira, R.R. (author), Draaisma, J.M.T. (author), TNO Kwaliteit van Leven (author)
article 2009
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TNO Kwaliteit van Leven (author), Verschuren, L. (author), van der Vries de Weij, J. (author), Zadelaar, A.S.M. (author), Kleemann, R. (author), Kooistra, T. (author)
The aim of this study was to define the anti-atherosclerotic role of liver-X-receptors (LXRs) under lesion progressive and lesion regressive conditions, to establish a temporal line of events, and to gain insights into the mechanisms underlying the anti-atherogenic potency of LXRs. We used apoE*3Leiden (E3L) mice to comprehensively and time...
article 2009
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Hack, W.W.M. (author), Sijstermans, K. (author), van der Voort-Doedens, L.M. (author), Meijer, R.W. (author), Heij, H.A. (author), Delemarre-van de Waal, H.A. (author), Pierik, F.H. (author), TNO Kwaliteit van Leven (author)
Undescended testis (UDT) is one of the most common urogenital abnormalities in boys. UDT is defined as a testis which cannot be brought into a stable scrotal position. At present, congenital and acquired forms of UDT are recognised. Congenital UDT is defined as a UDT which has never descended from birth. Acquired UDT is defined as a UDT which...
article 2008
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Lopatinskaya, L. (author), Zwemmer, J. (author), Uitdehaag, B. (author), Lucas, K. (author), Polman, C. (author), Nagelkerken, L. (author), TNO Kwaliteit van Leven (author)
TNF-α, IL-12p35, IL-12p40, IL-4, IL-10, TGF-β1, CCR3, CXCR3, CCR5, Fas and FasL mRNA levels in PBMC of 25 multiple sclerosis (MS) patients were quantified at baseline by real-time PCR according to a post-hoc study design. The baseline values of the different markers were analysed with respect to their correlation with the increase in disability...
article 2006
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Boxel van-Dezaire, A.H.H. (author), Smits, M. (author), Trigt van-Hoff, S.C.J. (author), Killestein, J. (author), Houwelingen, J.C van (author), Polman, C.H (author), Nagelkerken, L. (author), TNO Preventie en Gezondheid (author)
Little is known about the involvement of cytokines in the pathogenesis of primary progressive (PP) multiple sclerosis (MS). We evaluated in this cross-sectional study whether IL-18, IL-12p35, IL-12p40, TNF-α, IFN-γ, IL-10, IL-4, TGF-β, IL-12Rβ1, and IL-12Rβ2 mRNA expression in unstimulated white blood cells showed significant differences between...
article 2001
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't Hart, B.A. (author), Bank, R.A. (author), de Roos, J.A.D.M. (author), Brok, H. (author), Jonker, M. (author), Theuns, H.M. (author), Hakimi, J. (author), Koppele, J.M.Te. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The objective of this study was to analyse parameters in rhesus monkey collagen-induced arthritis (CIA) with which the inflammation and destruction of the joints can be described in quantitative terms. CIA was induced in genetically susceptible and resistant monkeys, which can be distinguished on the basis of the dominant resistance marker Mamu...
article 1998
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Instituut voor verouderings- en vaatziekten onderzoek TNO (author), HogenEsch, H. (author), Gijbels, M.J.J. (author), Offerman, E. (author), van Hooft, J. (author), van Bekkum, D.W. (author), Zurcher, C. (author)
Chronic proliferative dermatitis is a new spontaneous mutation in C57BL/Ka mice. Breeding results suggest an autosomal recessive mode of inheritance. Mutant mice develop skin lesions at the age of 5 to 6 weeks. The lesions occur in the ventral and dorsal skin of the body, whereas ears, footpads, and tail are not involved. The lesions are...
article 1993
Searched for: subject%3A%22Remission%22
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