Searched for: subject%3A%22Reflexes%22
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Steen, M. (author)
In this essay, the author reflects on several personal experiences in projects and advocates Slow Innovation as an alternative to the putative need for speed, the primacy of efficiency and the assumption that faster is better. Yes, RI does take time. Let us wear Slow Innovation as a badge of honour. Let us promote reflexivity: make time for...
article 2021
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Keemink, A.Q.L. (author), Brug, T.J.H. (author), van Asseldonk, E.H.F. (author), Wu, A.R. (author), van der Kooij, H. (author)
Active prosthetic and orthotic devices have the potential to increase quality of life for individuals with impaired mobility. However, more research into human-like control methods is needed to create seamless interaction between device and user. In forward simulations the reflex-based neuromuscular model (RNM) by Song and Geyer shows promising...
article 2021
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Young, H.J. (author), van Vliet, A.J. (author), van de Ven, J.G.S. (author), Jol, S.C. (author), Broekman, C.C.M.T. (author)
The perspective of human factors is largely missing from the wider cyber security dialogue and its scope is often limited. We propose a framework in which we consider cyber security as a state of a system. System change is brought on by an entity’s behavior. Interventions are ways of changing entities’ behavior to inhibit undesirable behavior...
conference paper 2018
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Duijnhoven, H.L. (author), Neef, R.M. (author)
This chapter discusses the complex challenge of dealing with diverging threats in our contemporary hyper-connected society. In recent decades, resilience has become a key notion that has been adopted by policy-makers and academia to embrace the changing risk our society faces. Yet the traditional, modernist rational logic that dominates...
bookPart 2016
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Duijnhoven, H. (author), Neef, M. (author)
This chapter discusses the complex challenge of dealing with diverging threats in our contemporary hyper-connected society. In recent decades, resilience has become a key notion that has been adopted by policy-makers and academia to embrace the changing risk our society faces. Yet the traditional, modernist rational logic that dominates...
bookPart 2015
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Steen, M.G.D. (author)
Contemporary design practices, such as participatory design (PD), human-centered design (HCD), and codesign, have inherent ethical qualities, which often remain implicit and unexamined. Three design projects in the high-tech industry were studied using three ethical traditions as lenses. Virtue ethics helped to understand cooperation, curiosity,...
article 2015
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Brouwer, A.M. (author), Hogervorst, M.A. (author), Holewijn, M. (author), van Erp, J.B.F. (author)
Learning to master a task is expected to be accompanied by a decrease in effort during task execution. We examine the possibility to monitor learning using physiological measures that have been reported to reflect effort or workload. Thirty-five participants performed different difficulty levels of the n-back task while a range of physiological...
article 2014
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Steen, M.G.D. (author)
In this essay several virtues are discussed that are needed in people who work in participatory design (PD). The term PD is used here to refer specifically to an approach in designing information systems with its roots in Scandinavia in the 1970s and 1980s. Through the lens of virtue ethics and based on key texts in PD, the virtues of...
article 2013
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Guzik, P. (author), Piskorski, J. (author), Krauze, T. (author), Schneider, R. (author), Wesseling, K.H. (author), Wykrȩtowicz, A. (author), Wysocki, H. (author), TNO Biomedical Instrumentation (author)
Aim: To analyze the correlation of the Poincaré plot descriptors of RR intervals with standard measures of heart rate variability (HRV) and spontaneous baroreflex sensitivity (BRS). A physiological model of changing respiratory rates from 6 to 15 breaths/min provided a wide range of RR intervals for analysis. Material and methods: Beat-to-beat...
article 2007
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TNO Defensie en Veiligheid (author), van Vliet, S.A.M. (author), Vanwersch, R.A.P. (author), Jongsma, M.J. (author), van der Gugten, J. (author), Olivier, B. (author), Philippens, I.H.C.H.M. (author)
The vigilance-enhancing agent modafinil has neuroprotective properties: it prevents striatal ischemic injury, nigrostriatal pathway deterioration after partial transsection and intoxication with 1-methyl-1,2,3,6-tetrahydropyridine. The present study determines the protective effects of modafinil in the marmoset 1-methyl-1,2,3,6...
article 2006
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TNO Defensie en Veiligheid (author), van Vliet, S.A.M. (author), Jongsma, M.J. (author), Vanwersch, R.A.P. (author), Olivier, B. (author), Philippens, I.H.C.H.M. (author)
Rationale: Modafinil is increasingly used in sleep disturbances in general and in neurodegenerative diseases and is recently being used in healthy people for attention control. However, the application of modafinil is possibly not only restricted to alertness enhancing effects. More insight in this compound may lead to new applications. Not all...
article 2006
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Bos, J.E. (author), van Erp, J.B.F. (author), Groen, E.L. (author), van Veen, H.J. (author), TNO Defensie en Veiligheid (author)
This paper shows that tactile stimulation can override vestibular information regarding spinning sensations and eye movements. However, we conclude that the current data do not support the hypothesis that tactile stimulation controls eye movements directly. To this end, twenty-four subjects were passively disoriented by an abrupt stop after an...
article 2005
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Wykretowicz, A. (author), Guzik, P. (author), Bartkowiak, G. (author), Krauze, T. (author), Kasinowski, R. (author), Dziarmaga, M. (author), Wesseling, K.H. (author), Wysocki, H. (author), TNO Biomedical Instrumentation (author)
Endothelial dysfunction and reduced BRS (baroreflex sensitivity) may be present in patients with CAD (coronary artery disease). The normal fasting glucose level does not exclude abnormal glucose metabolism in patients with CAD. The aim of present study was to evaluate endothelial function and BRS according to glucose metabolism in patients with...
article 2005
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Gisolf, J. (author), Westerhof, B.E. (author), van Dijk, N. (author), Wesseling, K.H. (author), Wieling, W. (author), Karemaker, J.M. (author), TNO Industrie (author)
Objectives We set out to determine the effect of sublingual nitroglycerin (NTG), as used during routine tilt testing in patients with unexplained syncope, on hemodynamic characteristics and baroreflex control of heart rate (HR) and systemic vascular resistance (SVR). Background Nitroglycerin is used in tilt testing to elicit a vasovagal response...
article 2004
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Westerhof, B.E. (author), Gisolf, J. (author), Stok, W.J. (author), Wesseling A, K.H. (author), Karemaker, J.M. (author), TNO Biomedical Instrumentation Technisch Physische Dienst TNO - TH (author)
Objective: To test a new method (cross-correlation baroreflex sensitivity, xBRS) for the computation of time-domain baroreflex sensitivity on spontaneous blood pressure and heart interval variability using the EUROBAVAR data set. Methods: We applied xBRS to the 42 records in the EUROBAVAR data set, obtained from 21 patients in the lying and...
article 2004
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Emmen, H.H. (author), Muijser, H. (author), Arts, J.H.E. (author), Prinsen, M.K. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)
The objective of this study was to establish the possible occurrence of eye irritation and subjective symptoms in human volunteers exposed to propylene glycol monomethyl ether (PGME) vapour at concentrations of 0, 100 and 150 ppm. Testing was conducted in 12 healthy male volunteers using a repeated measures design. Each subject was exposed for 2...
article 2003
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Wesseling, K.H. (author)
Chemicals/CAS: phenylephrine, 532-38-7, 59-42-7, 61-76-7; Cardiotonic Agents; Phenylephrine, 59-42-7
article 2003
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TNO Biomedical Instrumentation (author), Kingma, R. (author), Voorde, B.J.ten (author), Scheffer, G.J. (author), Karemaker, J.M. (author), Mackaay, A.J.C. (author), Wesseling, K.H. (author), Lange, J.J.de (author)
Endoscopic thoracic sympathectomy at T2-T4 is an effective and safe treatment for primary axillary and palmar hyperhidrosis and facial blushing refractory to conventional treatment. T2 and T4 ganglia however are in the direct pathway of sympathetic innervation of the heart and part of the vasomotor nerves. In this study we investigate possible...
article 2002
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TNO Technische Menskunde (author), Bos, J.E. (author), Bles, W. (author), de Graaf, B. (author)
Background: In the search for parameters to predict motion sickness that can be measured in the laboratory, we performed a longitudinal investigation in aviators. Since the vestibular system is involved in the generation of motion sickness as well as eye movements, vestibulo-ocular reflex (VOR) parameters seemed relevant. We investigated three...
article 2002
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Daanen, H.A.M. (author), Ducharme, M.B. (author), Netherlands Organisation Appl. S., Human Factors Research Institute (author)
Exposure of fingers to severe cold induces cold induced vasodilation (CIVD). The mechanism of CIVD is still debated. The original theory states that an axon reflex causes CIVD. To test this hypothesis, axon reflexes were evoked by electrical stimulation of the middle fingers of hands immersed in water at either 5°C or 35°C. Axon reflexes were...
article 2000
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