Searched for: subject%3A%22Refinement%22
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Burghouts, G.J. (author), Huizinga, W. (author)
Visual Question Answering (VQA) is a very interesting tech nique to answer natural language questions about an image. Recent methods have focused on incorporating knowledge into an improved VQA model, by augmenting the training set, representing scene graphs, or including reasoning. We also leverage knowledge to make VQA more robust. Yet we take...
conference paper 2022
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van Trijp, M.P.H. (author), Schutte, S. (author), Esser, D. (author), Wopereis, S. (author), Hoevenaars, F.P.M. (author), Hooiveld, G.J.E.J. (author), Afman, L.A. (author)
Background: Whole grain wheat (WGW) products are advocated as a healthy choice when compared with refined wheat (RW). One proposed mechanism for these health benefits is via the microbiota, because WGW contains multiple fibers. WGW consumption has been proposed to ameliorate nonalcoholic fatty liver disease, in which microbiota might play a role...
article 2021
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Geilen, M.C.W. (author), Skelin, M. (author), van Kampenhout, J.R. (author), Ara, H.A. (author), Basten, T. (author), Stuijk, S. (author), Goossens, K.G.W. (author)
bookPart 2020
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Bosilj, M. (author), Rustam, L. (author), Thomann, R. (author), Melke, J. (author), Fischer, A. (author), White, R.J. (author)
Selective hydrogenations in the aqueous phase are an important transformation in the context of developing biorefinery concepts. In this report the application and optimisation of nitrogen-doped carbon (NDC) supported Pd nanoparticles as hydrogenation catalysts is discussed in the context of directing support (e.g. N) chemistry for improved...
article 2020
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Janssen, R. (author), Tretmans, J. (author)
A well-known conformance relation for model-based testing is ioco. A conformance relation expresses when an implementation is correct with respect to a specification. Unlike many other conformance and refinement relations, ioco has different domains for implementations and for specifications. Consequently, ioco is neither reflexive nor...
conference paper 2019
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Janssen, R. (author), Vaandrager, F. (author), Tretmans, J. (author)
Various relations have been defined to express refinement and conformance for state-transition systems with inputs and outputs, such as and in the area of model-based testing, and alternating simulation and alternating-trace containment originating from game theory and formal verification. Several papers have compared these independently...
conference paper 2019
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Schutte, S. (author), Esser, D. (author), Hoevenaars, F.P.M. (author), Hooiveld, G.J.E.J. (author), Priebe, M.G. (author), Vonk, R.J. (author), Wopereis, S. (author), Afman, L.A. (author)
Background: Whole-grain wheat (WGW) is described as nutritionally superior to refined wheat (RW) and thus advocated as the healthy choice, although evidence from intervention studies is often inconsistent. The liver, as the central organ in energy metabolism, might be an important target organ for WGW interventions. Objective: The aim of this...
article 2018
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Blom, W.M. (author), Kruizinga, A.G. (author), Rubingh, C.M. (author), Remington, B.C. (author), Crevel, R.W.R. (author), Houben, G.F. (author)
Refined vegetable oils including refined peanut oil are widely used in foods. Due to shared production processes, refined non-peanut vegetable oils can contain residual peanut proteins. We estimated the predicted number of allergic reactions to residual peanut proteins using probabilistic risk assessment applied to several scenarios involving...
article 2017
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Leeuwenburgh, O. (author), Chitu, A.G. (author), Nair, R. (author), Egberts, P.J.P. (author), Ghazaryan, L. (author), Feng, T. (author), Hustoft, L. (author)
One of the main activities in the (re-)development of large hydrocarbon fields is the drilling of new wells. The drilling process may involve a large number of wells and take several years to complete. Challenges include the selection of a limited set of wells from many possible well paths, and the scheduling of the drilling itself....
conference paper 2016
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Delprat-Jannaud, F. (author), Pearce, J. (author), Akhurst, M. (author), Nielsen, C.M. (author), Neele, F. (author), Lothe, A. (author), Volpi, V. (author), Brunsting, S. (author), Vincké, O. (author)
The FP7-funded SiteChar project examined the entire CO<inf>2</inf> geological storage site characterisation process, from the initial feasibility studies through to the final stage of application for a CO<inf>2</inf> storage permit based on criteria defined by the relevant European legislation. The SiteChar workflow for CO<inf>2</inf> geological...
article 2015
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Koene, F.G.H. (author), de Kluizenaar, Y. (author), Bulavskaya, T. (author), Hoes-van Oeffelen, E.C.M. (author), Spiekman, M.E. (author), Hofstetter, H. (author), Opstelten, I.J. (author)
Generally, a discrepancy is observed between energy use for heating of dwellings, calculated by numerical models and actual energy use. This gap may be partially attributed to differences between assumed and actual occupant behavior. To account for the gap, a number of occupant behavioral models were made on thermostat settings, the likelihood...
article 2015
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Mulder, P. (author), Stavro, P.M. (author), Manuel Suárez, M. (author), Arola-Arnal, A. (author), van Duyvenvoorde, W. (author), Kooistra, T. (author), Wielinga, P.Y. (author), Kleemann, R. (author)
Background and Aims As dietary saturated fatty acids are associated with metabolic and cardiovascular disease, a potentially interesting strategy to reduce disease risk is modification of the quality of fat consumed. Vegetable oils represent an attractive target for intervention, as they largely determine the intake of dietary fats. Furthermore,...
article 2015
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Delprat-Jannaud, F. (author), Pearce, J. (author), Neele, F. (author), Akhurst, M. (author), Nielsen, C. (author), Mazurowski, M. (author), Lothe, A. (author), Volpi, V. (author), Brunsting, S. (author)
The FP7 SiteChar project has examined the entire site characterization chain, from the initial feasibility studies through to the final stage of application for a storage permit, on the basis of criteria defined by the relevant European legislation, highlighting important issues and recommendations such as the importance of a fit-to purpose...
conference paper 2014
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Schiffelers, M.J.W.A. (author), Blaauboer, B.J. (author), Bakker, W.E. (author), Beken, S. (author), Hendriksen, C.F.M. (author), Koeter, H. (author), Krul, C.A.M. (author)
Pharmaceuticals and chemicals are subjected to regulatory safety testing accounting for approximately 25% of laboratory animal use in Europe. This testing meets various objections and has led to the development of a range of 3R models to Replace, Reduce or Refine the animal models. However, these models must overcome many barriers before being...
article 2014
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ten Veen, J.H. (author), Doornenbal, J.C. (author), den Dulk, M. (author), van Gessel, S.F. (author), Witmans, N. (author)
In 2011, TNO-GDN concluded a 5 year geological mapping of the Netherlands Continental Shelf. In this project all public data from hydrocarbon exploration were used resulting in a major update of the dataset and a variety of deliverables available at www.NLOG.NL. The stratigraphy of more than 400 wells has been re-examined and amended where...
conference paper 2014
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Verreault, J. (author), Higgins, A.J. (author), Stowe, R.A. (author)
The structure of oblique detonation waves stabilized on a hypersonic wedge in mixtures characterized by a large activation energy is investigated via steady method of characteristics (MoC) calculations and unsteady computational flowfield simulations. The steady MoC solutions show that, after the transition from shock-induced combustion to an...
conference paper 2013
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Baumans, V. (author), van Loo, P.L.P. (author)
Housing systems for captive animals have often been designed on the basis of economic and ergonomic considerations, such as equipment, costs, space, workload, ability to observe the animals and to maintain a certain degree of hygiene, with little or no consideration for animal welfare. Environmental refinement can be defined as any modification...
article 2013
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Punt, A. (author), Schiffelers, M.J.W.A. (author), Jean Horbach, G. (author), van de Sandt, J.J.M. (author), Groothuis, G.M.M. (author), Rietjens, I.M.C.M. (author), Blaauboer, B.J. (author)
The present paper aims at identifying strategies to increase the impact and applicability of alternative testing strategies in risk assessment. To this end, a quantitative and qualitative literature evaluation was performed on (a) current research efforts in the development of in vitro methods aiming for alternatives to animal testing, (b) the...
article 2011
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Sanchez Fernandez, E. (author), Goetheer, E.L.V. (author)
This work describes the conceptual design of a novel separation process for CO2 removal from flue gas based on precipitating solvents. The process here described (DECAB) is an enhanced CO2 absorption based on the Le Chatelier's principle, which states that reaction equilibrium can be shifted by removing one of the constituents in the reaction. A...
conference paper 2011
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Tluczkiewicz, I. (author), Buist, H.E. (author), Martin, M.T. (author), Mangelsdorf, I. (author), Escher, S.E. (author)
The present report describes a strategy to refine the current Cramer classification of the TTC concept using a broad database (DB) termed TTC RepDose. Cramer classes 1-3 overlap to some extent, indicating a need for a better separation of structural classes likely to be toxic, moderately toxic or of low toxicity.Groups of structurally similar...
article 2011
Searched for: subject%3A%22Refinement%22
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