Pages
- 1
- 2
- document
-
Smits, M. (author), Verhoeckx, K. (author), Knulst, A. (author), Welsing, P. (author), de Jong, A. (author), Houben, G.F. (author), Le, T.M. (author)Predicting the allergenicity of novel proteins is challenging due to the absence of validated predictive methods and a well-defined reference set of proteins. The prevalence of sensitization could be a parameter to select reference proteins to characterize allergenic proteins. This study investigated whether the prevalence of sensitization of...article 2021
- document
-
Franken, R. (author), Heringa, M.B. (author), Oosterwijk, T. (author), dal Maso, M. (author), Fransman, W. (author), Kanerva, T. (author), Liguori, B. (author), Poikkimäki, M. (author), Rodriguez-Llopis, I. (author), Säämänen, A. (author), Stockmann-Juvala, H. (author), Suarez-Merino, B. (author), alstrup Jensen, K. (author), Stierum, R. (author)The current work describes the interaction with various stakeholder groups to establish consensus on stage-gate specific criteria that human risk assessment (HRA) models for manufactured nanomaterials (MN) need to comply with. During the decisive steps in the innovation process, which can be described in a simplified way as stage-gates, it is...article 2020
- document
-
Zwetsloot, G. (author), van Kampen, J.N. (author), Steijn, W. (author), Post, S. (author)Although major hazard industries have no legal obligations to demonstrate a good safety culture, it is an increasingly important factor for risk-based inspections. This paper describes the development and evaluation of a relatively simple method for external indicative assessment of the process safety culture in major hazard industries. As a...article 2020
- document
- Paprotny, D (author), Morales-Nápoles, (author), Worm, D.T.H. (author), Ragno, E. (author) article 2020
- document
-
Zillien, C. (author), van Loon, C. (author), Gulpen, M. (author), Tipatet, K. (author), Hanssen, B. (author), Beeltje, H. (author), Roex, E. (author), Oldenkamp, R. (author), Posthuma, L. (author), Ragas, A.M.J. (author)Over the past decade, the health care sector has becomeincreasingly aware of the impact of pharmaceutical emissions to the environment. Yet, it remains unclearwhich compounds are the most relevant to address and at what point emission control is most effective. This study presents a modelling framework to prioritize pharmaceuticals based on...article 2019
- document
-
Akesson, B. (author), Hooman, J. (author), Dekker, R. (author), Ekkelkamp, W. (author), Stottelaar, B. (author)Changing an established way of working can be a real headache. This is particularly true if there are high stakes involved, e.g., when changing the development process for complex systems. New design methods, such as model-based engineering (MBE) using domain-specific languages (DSLs) promise significant gains, such as cost reductions and...conference paper 2018
- document
-
Brouwer, R.F.T. (author), Stuiver, A. (author), Hof, T. (author), Kroon, L. (author), Pauwelussen, J. (author), Holleman, B. (author)Conventional road transport has negative impact on the environment. Stimulating eco-driving through feedback to the driver about his/her energy conservation performance has the potential to reduce CO<inf>2</inf> emissions and promote fuel cost savings. Not all drivers respond well to the same type of feedback. Research has shown that different...article 2015
- document
-
de Boer, M.H.T. (author), Daniele, L.M. (author), Brandt, P. (author), Sappelli, M. (author)Abstract—With the growth of open sensor networks, multiple applications in different domains make use of a large amount of sensor data, resulting in an emerging need to search semantically over heterogeneous datasets. In semantic search, an important challenge consists of bridging the semantic gap between the high-level natural language query...conference paper 2015
- document
-
Kaptein, R. (author), Kamps, J. (author)In this paper we investigate how the category structure of Wikipedia can be exploited for Entity Ranking. In the last decade, theWeb has not only grown in size, but also changed its character, due to collaborative content creation and an increasing amount of structure. Current Search Engines find Web pages rather than information or knowledge,...conference paper 2013
- document
-
Strikwold, M. (author), Woutersen, R.A. (author), Spenkelink, B. (author), Punt, A. (author), Rietjens, I.M.C.M. (author)The applicability of the embryonic stem cell test (EST) as an alternative for in vivo embryotoxicity testing was evaluated for a series of five p-substituted phenols. To this purpose, the potency ranking for this class of compounds derived from the inhibition of cardiomyocyte differentiation in the EST was compared to in vivo embryotoxic potency...article 2012
- document
-
Toet, A. (author)The predictions of 13 computational bottom-up saliency models and a newly introduced Multiscale Contrast Conspicuity (MCC) metric are compared with human visual conspicuity measurements. The agreement between human visual conspicuity estimates and model saliency predictions is quantified through their rank order correlation. The maximum of the...article 2011
- document
-
Verberne, S. (author), van Halteren, H. (author), Theijssen, D. (author), Raaijmakers, S.A. (author), Boves, L. (author)In this paper, we evaluate a number of machine learning techniques for the task of ranking answers to why-questions. We use TF-IDF together with a set of 36 linguistically motivated features that characterize questions and answers. We experiment with a number of machine learning techniques (among which several classifiers and regression...article 2011
- document
-
Hofman, W. (author), van Staalduinen, M. (author), TNO Informatie- en communicatietechnologie (author)This paper presents an approach to dynamic public service mediation. It is based on a conceptual model and the use of search and ranking algorithms. The conceptual model is based on Abstract State Machine theory. Requirements for dynamic service mediation were derived from a real-world case. The conceptual model and the algorithms are developed...conference paper 2010
- document
-
Wijnmalen, D.J.D. (author), Wedley, W.C. (author), TNO Defensie en Veiligheid (author)This note comments on a paper by Triantaphyllou (J. Multi-Crit. Decis. Anal. 2001; 10: 11–25) that attempts to demonstrate new types of rank reversal that can occur with the analytic hierarchy process (AHP). He contends that the reversals are attributable to the various types of normalization that are used with the addition step in AHP synthesis...article 2009
- document
-
Wijnmalen, D.J.D. (author), Wedley, W.C. (author), TNO Defensie en Veiligheid (author)A non-discriminating criterion is defined as a criterion where the decision-maker is indifferent among the alternatives. One would therefore expect the final rank order of the alternatives not to be affected by removing it. A previously published paper by Finan and Hurley (Comput. Oper. Res. 2002; 29: 1025–1030) showed that in the analytic...article 2009
- document
-
Molag, M.L. (author), de Vries, J.H.M. (author), Ocké, M.C. (author), Dagnelie, P.C. (author), van den Brandt, P.A. (author), Jansen, M.C.J.F. (author), van Staveren, W.A. (author), van 't Veer, P. (author), TNO Kwaliteit van Leven (author)The authors investigated the role of food frequency questionnaire (FFQ) design, including length, use of portion-size questions, and FFQ origin, in ranking subjects according to their nutrient intake. They also studied the ability of the FFQ to detect differences in energy intake between subgroups and to assess energy and protein intake. In a...article 2007
- document
-
Mandelin, J. (author), Hukkanen, M. (author), Li, T.F. (author), Korhonen, M. (author), Liljeström, M. (author), Sillat, T. (author), Hanemaaijer, R. (author), Salo, J. (author), Santavirta, S. (author), Konttinen, Y.T. (author), TNO Kwaliteit van Leven (author)Healthy bone is a rigid yet living tissue that undergoes continuous remodeling. Osteoclasts resorb bone in the remodeling cycle. They secrete H+-ions and proteinases to dissolve bone mineral and degrade organic bone matrix, respectively. One of the main collagenolytic proteinase in osteoclasts is cathepsin K, a member of papain family cysteine...article 2006
- document
-
Wijnmalen, D.J.D. (author), Wedley, W.C. (author)A non-discriminating criterion is defined as a criterion where the decision-maker is indifferent among the alternatives. One would therefore expect the final rank order of the alternatives not to be affected by removing it. A previously published paper by J.S. Finan and W.J. Hurley (2002) showed, however, that in the Analytic Hierarchy Process...conference paper 2004
- document
-
van Haelst, A.G. (author), Hansen, B.G. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)One of the four steps within Council Regulation 793/93/EEC on the evaluation and control of existing chemicals is the priority setting step. The priority setting step is concerned with selecting high-priority substances from a large number of substances, initially starting with 2,474 high-production-volume chemicals. In order to be able to...article 2000
- document
-
Neef, R.M. (author), Thierens, D. (author), Arciszewski, H.F.R. (author), TNO Fysisch en Elektronisch Laboratorium (author)We present a multiobjective genetic algorithm that incorporates various genetic algorithm techniques that have been proven to be efficient and robust in their problem domain. More specifically, we integrate rank based selection, adaptive niching through coevolutionary sharing, elitist recombination, and non-dominated sorting into a...conference paper 1999
Pages
- 1
- 2