Searched for: subject%3A%22Randomization%22
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Stroek, K. (author), Visser, A. (author), van der Ploeg, C.P.B. (author), Zwaveling-Soonawala, N. (author), Heijboer, A.C. (author), Bosch, A.M. (author), van Trotsenburg, P. (author), Boelen, A. (author), Hoogendoorn, M. (author), de Jonge, R. (author)
Objective. The Dutch Congenital hypothyroidism (CH) Newborn Screening (NBS) algorithm for thyroidal and central congenital hypothyroidism (CH-T and CH-C, respectively) is primarily based on determination of thyroxine (T4) concentrations in dried blood spots, followed by thyroid-stimulating hormone (TSH) and thyroxine-binding globulin (TBG)...
article 2023
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Fluitman, K.S. (author), Wijdeveld, M. (author), Davids, M. (author), van Ruiten, C.C. (author), Reinders, I. (author), Wijnhoven, H.A.H. (author), Keijser, B.J.F. (author), Visser, M. (author), Nieuwdorp, M. (author), IJzerman, R.G. (author)
Expert groups argue to raise the recommended daily allowance for protein in older adults from 0.8 to 1.2 g/kg/day to prevent undernutrition. However, protein is thought to increase satiety, possibly through effects on gut microbiota and central appetite regulation. If true, raising daily protein intake may work counterproductively. In a...
article 2023
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Maljaars, J. (author), Leonetti, D. (author), Hashemi, B. (author), Snijder, H.H.B. (author)
This paper presents a probabilistic framework to derive the safety factors for fatigue of steel and composite steel concrete road bridges. Engineering models are used for the design and the safety factor is derived in such a way that the design meets the target reliability set by international Eurocode and ISO standards, estimated using measured...
article 2022
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Raftopoulou, M. (author), Litjens, R. (author), van Mieghem, P. (author)
In this paper, we focus on the link density in random geometric graphs (RGGs) with a distance-based connection function. After deriving the link density in D dimensions, we focus on the two-dimensional (2D) and three-dimensional (3D) space and show that the link density is accurately approximated by the Fréchet distribution, for any rectangular...
article 2022
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Westerneng, M. (author), de Jonge, A. (author), van Baar, A.L. (author), Witteveen, A.B. (author), Jellema, P. (author), Paarlberg, K.M. (author), Rijnders, M. (author), van der Horst, H.E. (author)
Background: Third-trimester routine ultrasounds are increasingly offered to monitor fetal growth. In addition to limited evidence for its clinical effectiveness, little is known about its importance for pregnancy-specific anxiety and mother-to-infant bonding. Methods: 1275 low-risk women participated in a Dutch nationwide pragmatic cluster...
article 2022
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van der Burg, E. (author), Toet, A. (author), Brouwer, A.M. (author), van Erp, J.B.F. (author)
How we perceive the world is not solely determined by what we sense at a given moment in time, but also by what we processed recently. Here we investigated whether such serial dependencies for emotional stimuli transfer from one modality to another. Participants were presented a random sequence of emotional sounds and images and instructed to...
article 2022
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Zou, H. (author), Dorsman, J.L. (author), Mandjes, M. (author), Snelder, M. (author)
Activity-based travel demand modeling (ABM) provides a very high level of detail when modeling complex travel behavior of individuals. Since stochastic simulation is used, however, the high level of detail may induce a large random fluctuation in the output, necessitating (possibly) excessively many model reruns to produce reliable output. This...
conference paper 2022
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van Verseveld, M.D.A. (author), Fekkes, M. (author), Fukkink, R.G. (author), Oostdam, R.J. (author)
This study investigates the effectiveness of the PRIMA antibullying program for elementary education using a cluster-randomized trial with two experimental conditions (with and without student lessons) and a control group. Students of 31 schools participated in the study (N = 3,135; Mage = 10 years). Multilevel regression analyses demonstrated...
article 2021
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Ragamin, A. (author), Fieten, K.B. (author), Tupker, R.A. (author), de Wit, J. (author), van Mierlo, M.M.F. (author), Jansen, M.S. (author), Bronner, M.B. (author), Schappin, R. (author), Schuren, F.H.J. (author), Romeijn, M.L.E. (author), Arents, B.W.M. (author), Suzanne, (author), Polinder, S. (author), de Graaf, M. (author), Rustemeyer, T. (author), Schuttelaar, M.L.A. (author), Pasmans, S.G.M.A. (author)
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects 10 to 20% of children and between 2 and 15% of the adults in Western Europe. Since 2000, therapeutic clothing or functional textiles based on silver or chitosan as antibacterial agents were introduced for AD. These agents aim to reduce skin colonization with...
article 2021
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Patel, N. (author), Adelman, D.C. (author), Anagnostou, K. (author), Baumert, J.L. (author), Blom, W.M. (author), Campbell, D.E. (author), Chinthrajah, R.S. (author), Mills, E.N.C. (author), Javed, B. (author), Purington, N. (author), Remington, B.C. (author), Sampson, H.A. (author), Smith, A.D. (author), Yarham, R.A.R. (author), Turner, P.J. (author)
Background Eliciting doses (EDs) (eg, ED01 or ED05 values, which are the amounts of allergen expected to cause objective symptoms in 1% and 5% of the population with an allergy, respectively) are increasingly being used to inform allergen labeling and clinical management. These values are generated from food challenge, but the frequency of...
article 2021
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van Santen, J. (author), Dröes, R.M. (author), Twisk, J.W.R. (author), Blanson Henkemans, O.A. (author), van Straten, A. (author), Meiland, F.J.M. (author)
Objectives: Physical activity in people with dementia (PwD) may enhance physical and mental functioning. Exergaming, which combines physical exercise with cognitive stimulation in a gaming environment, was developed to overcome barriers in performing physical activities. We evaluated the effects of exergaming in day care centers (DCCs) for PwD...
article 2021
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Diallo, M. (author), Akesson, B. (author), Bera, D. (author), Begeer, R. (author)
There are many classes of Petri nets for describing communicating systems. Some of these guarantee important properties, such as termination in the case of portnets. There are also many methods and tools available for their analysis and synthesis. However, when developing new methods, or benchmarking against existing ones, it is often helpful to...
conference paper 2021
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Humalda, J.K. (author), Klaassen, G. (author), de Vries, H. (author), Meuleman, Y. (author), Verschuur, L.C. (author), Straathof, E.J.M. (author), Laverman, G.D. (author), Bos, W.J.W. (author), van der Boog, P.J.M. (author), Vermeulen, K.M. (author), Blanson Henkemans, O.A. (author), Otten, W. (author), de Borst, M.H. (author), van Dijk, S. (author), Navis, G.J. (author)
Rationale & objective: Patients with chronic kidney disease (CKD) are particularly sensitive to dietary sodium. We evaluated a self-management approach for dietary sodium restriction in patients with CKD. Study design: Randomized controlled trial. Setting & participants: Nephrology outpatient clinics in 4 Dutch hospitals. 99 adults with CKD...
article 2020
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Offringa, A. (author), Montijn, R. (author), Singh, S. (author), Paul, M. (author), Pinto, Y.M. (author), Pinto-Sietsma, S.J. (author)
The SARS-CoV-2 pandemic is a healthcare crisis caused by insufficient knowledge applicable to effectively combat the virus. Therefore, different scientific discovery strategies need to be connected, to generate a rational treatment which can be made available as rapidly as possible. This relies on a solid theoretical understanding of the...
article 2020
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Memelink, R. (author), Bongers, A. (author), Pasman, W. (author), van Rijmenam, M. (author), Wopereis, S. (author), Verlaan, G. (author), de Vogel Van den Bosch, J (author), Weijs, P.J.M. (author)
Objectives. Weight loss is a key element in the treatment of obesity and type 2 diabetes (T2D), but also a risk factor for lean mass (LM) loss in older adults. We evaluated whether a whey protein drink enriched with leucine and vitamin D preserved LM during 3-month lifestyle intervention and whether effects sustained during 6 months follow-up...
article 2020
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Pot, M. (author), Paulussen, T.G. (author), Ruiter, R.A. (author), Eekhout, I. (author), de Melker, H.E. (author), Spoelstra, M.E. (author), van Keulen, H.M. (author)
article 2020
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Pot, M. (author), Paulussen, T.G. (author), Ruiter, R.A. (author), Hofstra, M. (author), van Keulen, H.M. (author)
Background: In the Netherlands, human papillomavirus (HPV) vaccination uptake remains low. To improve informed decision making (IDM) and HPV vaccination acceptability, we systematically developed an interactive, web-based tailored intervention to which mothers of Dutch girls were invited to participate. Objective: The aim of this study was to...
article 2020
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Coenen, P. (author), Robroek, S.J.W. (author), van der Beek, A.J. (author), Boot, C.R.L. (author), van Lenthe, F.J. (author), Burdorf, A. (author), Oude Hengel, K.M. (author)
Background: This individual patient data (IPD) meta-analysis aimed to investigate socioeconomic inequalities in effectiveness on healthy behavior of, and compliance to, workplace health promotion programs. Methods: Dutch (randomized) controlled trials were identified and original IPD were retrieved and harmonized. A two-stage meta-analysis was...
article 2020
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Schoen, E.D. (author), Wopereis, S. (author)
BACKGROUND: Parallel intervention studies involving volunteers usually require a procedure to allocate the subjects to study-arms. Statistical models to evaluate the different outcomes of the study-arms will include study-arm as a factor along with any covariate that might affect the results. To ensure that the effects of the covariates are...
article 2020
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Hoevenaars, F.P.M. (author), Berendsen, C.M.M. (author), Pasman, W.J. (author), van den Broek, T.J. (author), Barrat, E. (author), de Hoogh, I.M. (author), Wopereis, S. (author)
In public health initiatives, generic nutrition advice (GNA) from national guidelines has a limited effect on food-intake improvement. Personalized nutrition advice (PNA) may enable dietary behavior change. A monocentric, randomized, parallel, controlled clinical trial was performed in males (n = 55) and females (n = 100) aged 25 to 70 years....
article 2020
Searched for: subject%3A%22Randomization%22
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