Searched for: subject%3A%22Radioimmunoassay%22
(1 - 12 of 12)
document
Hoeijmakers, M. (author), Janszen, B. (author), Coert, A. (author), Horspool, L. (author), TNO Voeding (author)
The aim of the present study was to investigate the pharmacokinetics of oestriol in plasma in the dog after repeated oral administration of oestriol tablets, a preparation intended for the treatment of urinary incontinence in the bitch. The study was performed in six healthy, entire, adult female beagle dogs. The bitches were treated once daily...
article 2003
document
Vázquez-Martínez, R.M. (author), Malagón, M.M. (author), van Strien, F.J.C. (author), Jespersen, S. (author), van der Greef, J. (author), Roubos, E.W. (author), Gracia-Navarro, F. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
We have previously shown that the melanotrope population of the pituitary intermediate lobe of Rana ridibunda is composed of two subpopulations, of low (LD) and high density (HD), that show distinct ultrastructural features and display different synthetic and secretory rates. To investigate whether LD and HD melanotrope cells also differ in...
article 1999
document
Gerrits, W.J.J. (author), Decuypere, E. (author), Verstegen, M.W.A. (author), Karabinas, V. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
We conducted two experiments with preruminant calves weighing 80 to 240 kg to study the long-term nutritional regulation of circulating IGF-I, thyroxine (T4), and triiodothyronine (T3). The two experiments were similar in design but were performed with calves of two live weight ranges: 80 to 160 kg (Exp. 1) and 160 to 240 kg (Exp. 2). In each...
article 1998
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Gimeno, S. (author), Komen, H. (author), Gerritsen, A.G.M. (author), Bowmer, T. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
In recent years, a hierarchy of techniques has become available for detecting chemicals which may cause endocrine
article 1998
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Elliott, C.T. (author), Baxter, G.A. (author), Hewitt, S.A. (author), Arts, C.J.M. (author), van Baak, M. (author), Hellenäs, K.-E. (author), Johannson, A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The drug salbutamol (SBL) is a β-agonist that may be used illegally as an animal growth promoter. SBL is also a good example of a drug which is excreted in the form of glucuronides and sulfates. Such metabolites cause complexities in analysing for the presence of drug residues. In the majority of cases a process of deconjugation and sample clean...
article 1998
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Hartmann, D. (author), Güzelhan, C. (author), Zuiderwijk, P.B.M. (author), Odink, J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Objectives: Orlistat, a potent and selective inhibitor of gastrointestinal lipases, is designed for the treatment of obesity. A double-blind, randomised, placebo-controlled, 2-way crossover study investigated the possible influence of orlistat on the ovulation-suppressing action of combination oral contraceptives (OC). Methods: After an 8-day...
article 1996
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Bruinse, H.W. (author), van den Berg, H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Most vitamin status parameters change significantly during pregnancy. A number of factors have been associated with this hypovitaminaemia of pregnancy. From our data, it was concluded that the initial value of a vitamin status parameter was by far the main determinant of the changes of vitamin levels during pregnancy: the higher the value, the...
article 1995
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van Nesselrooij, J.H.J. (author), Bruijntjes, J.P. (author), Garderen van-Hoetmer, A. (author), Tillapaugh-Fay, G.M. (author), Feron, V.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Estrogen-induced pituitary lesions in rats were studied in time-sequence experiments using magnetic resonance imaging (MRI), hormone determinations and light microscopy. The main purpose of the study was to evaluate the usefulness of MRI in comparison with conventional biochemical and histopathological methods for detecting the pituitary lesions...
article 1991
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Centraal Instituut voor Voedingsonderzoek TNO (author), van der Greef, J. (author), Tas, A.C. (author), Rijk, M.A.H. (author), ten Noever de Brauw, M.C. (author)
Progesterone can be determined rapidly and accurately with the method presented, using isotope dilution LC-MS with a moving-belt interface. Deactivation is very useful in that it minimizes belt memory effects and optimizes belt desorption characteristics. Since the moving-belt properties were found to change during time with respect to the...
article 1985
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Schreurs, W.H.P. (author), van Rijn, H.J.M. (author), van den Berg, H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
A study has been made of the serum 25-hydroxycholecalciferol (25-HCC) levels in six groups of women. Significant differences were found between the one pregnant group and the two reference groups as well as between the one pregnant group and two of the three groups using oral contraceptives. No significant differences were found between the...
article 1981
document
Nooijen, W.J. (author), Koppert, P.W. (author), Gaubius instituut TNO (author)
A specific glucagon antiserum was generated in rabbits using a derivatisation of the methionine residue in glucagon. A sensitive and specific assay for glucagon has been developed. Interference with the assay system by plasma factors was abolished by both extraction of plasma samples and the production of glucagon-free plasma for each individual...
article 1981
document
Westenbrink, F. (author), Koornstra, W. (author), Creemers, P. (author), Radiobiologisch Instituut TNO (author)
Antisera raised in rabbits against purified components gp52, p28 and p12 of murine mammary tumor virus (MuMTV) were first characterized by means of immunodiffusion, immunoelectrophoresis and radioimmunoassay. No significant crossreactivity could be detected. The 3 polypeptides were detected by means of these antisera in the cytoplasm of murine...
article 1979
Searched for: subject%3A%22Radioimmunoassay%22
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