Searched for: subject%3A%22RAPID%255C%2B%255C-%255C%2BRisk%255C%2BAnalysis%255C%2Bfor%255C%2BProducts%255C%2Bin%255C%2BDevelopment%255C%2BEMS%255C%2B%255C-%255C%2BEnvironmental%255C%2BModelling%252C%255C%2BSensing%255C%2B%2526%255C%2BAnalysis%22
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Dankers, A.C.A. (author), Kuper, C.F. (author), Boumeester, A.J. (author), Fabriek, B.O. (author), Kooter, I.M. (author), Gröllers-Mulderij, M. (author), Tromp, P. (author), Nelissen, I. (author), Zondervan-Van Den Beuken, E.K. (author), Vandebriel, R.J. (author)Exposure of humans to metal oxide nanoparticles (NPs) occurs mainly via air, and inhaled metal oxide NPs may generate inflammation. The aim of this study was to investigate the proinflammatory potential of six metal oxide NPs (CeO2, Mn2O3, CuO, ZnO, Co3O4 and WO3; 27–108 μg ml−1) using human primary 3-dimensional airway epithelium (MucilAir™)...article 2018
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Hiemstra, P.S. (author), Grootaers, G.G. (author), van der Does, A.M. (author), Krul, C.A.M. (author), Kooter, I.M. (author)The epithelium that covers the conducting airways and alveoli is a primary target for inhaled toxic substances, and therefore a focus in inhalation toxicology. The increasing concern about the use of animal models has stimulated the development of in vitro cell culture models for analysis of the biological effects of inhaled toxicants. However,...article 2018
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de Kluizenaar, Y. (author), Kuijpers, E. (author), Eekhout, I. (author), Voogt, M. (author), Vermeulen, R.C.H. (author), Hoek, G. (author), Sterkenburg, R.P. (author), Pierik, F.H. (author), Duyzer, J.H. (author), Meijer, E.W. (author), Pronk, A. (author)Particulate matter exposure may cause adverse health effects. Although ultrafine particulate matter (UFP) is hypothesised to be particularly health relevant, the number of studies into personal UFP exposure is limited. Aim To increase insight where and when most UFP exposure occurs, in terms of exposure levels and peaks in microenvironments,...article 2017
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Jedynska, A. (author), Hoek, G. (author), Wang, M. (author), Yang, A. (author), Eeftens, M. (author), Cyrys, J. (author), Keuken, M. (author), Ampe, C. (author), Beelen, R. (author), Cesaroni, G. (author), Forastiere, F. (author), Cirach, M. (author), de Hoogh, K. (author), de Nazelle, A. (author), Nystad, W. (author), Akhlaghi, H.M. (author), Declercq, C. (author), Stempfelet, M. (author), Eriksen, K.T. (author), Dimakopoulou, K. (author), Lanki, T. (author), Meliefste, K. (author), Nieuwenhuijsen, M. (author), Yli-Tuomi, T. (author), Raaschou-Nielsen, O. (author), Janssen, N.A.H. (author), Brunekreef, B. (author), Kooter, I.M. (author)Oxidative potential (OP) has been suggested as a health-relevant measure of air pollution. Little information is available about OP spatial variation and the possibility to model its spatial variability. Our aim was to measure the spatial variation of OP within and between 10 European study areas. The second aim was to develop land use...article 2017
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Schinkel, J.M. (author), den Boeft, J. (author), Tromp, P.C. (author), de Jonge, M. (author)Deze rapportage beschrijft een gesimuleerd werkplek beschermingsfactor (SWPF) onderzoek waarin de beschermingsfactoren van de 8 meest gebruikte adembeschermingsmiddelen (ABM) in de asbestbranche zijn onderzocht. De nieuwe ABM systemen werden, nadat de testpersoon een fittest had gepasseerd, getest in een testkamer waar voor elk systeem 11 voor...report 2017
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Cellular response of mucociliary differentiated primary bronchial epithelial cells to diesel exhaustZarcone, M.C. (author), Duistermaat, E. (author), van Schadewijk, A. (author), Jedynksa, A.D. (author), Hiemstra, P.S. (author), Kooter, I.M. (author)Cellular response of mucociliary differentiated primary bronchial epithelial cells to diesel exhaust. Am J Physiol Lung Cell Mol Physiol 311: L111–L123, 2016. First published May 17, 2016; doi:10.1152/ajplung.00064.2016.—Diesel emissions are the main source of air pollution in urban areas, and diesel exposure is linked with substantial adverse...article 2016
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