Harmonization of measurement strategies for exposure to manufactured nano-objects; Report of a workshop

The present paper summarizes the outcome of the discussions at the First International Scientific Workshop on Harmonization of Strategies to Measure and Analyze Exposure to (Manufactured) Nano-objects in Workplace Air that was organized and hosted by the Netherlands Organization for Applied Scientific Research (TNO) and the Institute for...

Advanced REACH Tool: Development and application of the substance emission potential modifying factor

The Advanced REACH Tool (ART) is an exposure assessment tool that combines mechanistically modelled inhalation exposure estimates with available exposure data using a Bayesian approach. The mechanistic model is based on nine independent principal modifying factors (MF). One of these MF is the substance emission potential, which addresses the...

Revisiting the effect of room size and general ventilation on the relationship between near- and far-field air concentrations

Objectives: In 1999, Cherrie carried out a series of mathematical simulations to investigate dispersion of pollutants through two indoor zones: the near-field (NF) and the far-field (FF). The results of these simulations were used to derive modifying factors for use in exposure modeling. However, in the original simulations, no account was taken...

Advanced reach tool (ART): Development of the mechanistic model

This paper describes the development of the mechanistic model within a collaborative project, referred to as the Advanced REACH Tool (ART) project, to develop a tool to model inhalation exposure for workers sharing similar operational conditions across different industries and locations in Europe. The ART mechanistic model is based on a...