A Novel, Orally Bioavailable, Small-Molecule Inhibitor of PCSK9 With Significant Cholesterol-Lowering Properties In Vivo

The mechanistic overview of SARS-CoV-2 using angiotensin-converting enzyme 2 to enter the cell for replication Possible treatment options related to the renin-angiotensin system

Proteomics of human liver membrane transporters: a focus on fetuses and newborn infants

The advantage of laser-capture microdissection over whole tissue analysis in proteomic profiling studies

Effects of anthocyanin and flavanol compunds on lipid metabolism and adipose tissue associated systemic inflammation in diet-induced obesity

Spatiotemporal proliferation of human stromal cells adjusts to nutrient availability and leads to stanniocalcin-1 expression in vitro and in vivo

Are zebrafish larvae suitable for assessing the hepatotoxicity potential of drug candidates?

The probiotic mixture VSL#3 has differential effects on intestinal immune parameters in healthy female BALB/c and C57BL/6 mice

Generation of Bayesian prediction models for OATP-mediated drug-drug interactions based on inhibition screen of OATP1B1, OATP1B1∗15 and OATP1B3

Anacetrapib reduces (V)LDL-cholesterol by inhibition of CETP activity and reduction of plasma PCSK9

Innovative pharmaceutical interventions in cardiovascular disease: Focusing on the contribution of non-HDL-C/LDL-C-lowering versus HDL-C-raisingA systematic review and meta-analysis of relevant preclinical studies and clinical trials

Elevated expression levels of lysyl oxidases protect against aortic aneurysm progression in Marfan syndrome

Predicting individual responses to pravastatin using a physiologically based kinetic model for plasma cholesterol concentrations

Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression

A dietary mixture containing fish oil, resveratrol, lycopene, catechins, and vitamins E and C reduces atherosclerosis in transgenic mice

Probing the proteome response to toluene exposure in the solvent tolerant pseudomonas putida S12

Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models

Aspirin reduces hypertriglyceridemia by lowering VLDL-triglyceride production in mice fed a high-fat diet

Dietary acrylamide intake and estrogen and progesterone receptor-defined postmenopausal breast cancer risk

Butyrate enemas do not affect human colonic MUC2 and TFF3 expression