Searched for: subject%3A%22Prognosis%22
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Kim, C. (author), Colborn, K. (author), van Buuren, S. (author), Loar, T. (author), Stevens-Lapsley, J.E. (author), Kittelson, A.J. (author)
The purpose of this study was to develop and test personalized predictions for functional recovery after Total Knee Arthroplasty (TKA) surgery, using a novel neighbors-based prediction approach. We used data from 397 patients with TKA to develop the prediction methodology and then tested the predictions in a temporally distinct sample of 202...
article 2021
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Bourgonje, A.R. (author), Offringa, A.K. (author), van Eijk, L.E. (author), Abdulle, A.E. (author), Hillebrands, J.L. (author), van der Voort, P.H.J. (author), van Goor, H. (author), van Hezik, E.J. (author)
Significance: Hydrogen sulfide (H2S) is one of the three main gasotransmitters that are endogenously produced in humans and are protective against oxidative stress. Recent findings from studies focusing on coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), shifted our attention to a...
article 2021
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van Vilsteren, M. (author), Boot, C. (author), Twisk, J.W.R. (author), van Schaardenburg, D. (author), Steenbeek, R. (author), Voskuyl, A.E. (author), Anema, J.R. (author)
Purpose: In this manuscript, we evaluated the effectiveness of an intervention programme consisting of integrated care and a participatory workplace intervention on supervisor support, work instability and at-work productivity after 6 months of follow-up among workers with rheumatoid arthritis (RA). Methods: We conducted a randomized controlled...
article 2017
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Elings, J. (author), Hoogeboom, T.J. (author), van der Sluis, G. (author), van Meeteren, N. (author)
Objective: To identify the preoperative patient-related characteristics predicting inpatient recovery of functioning and/or length of hospital stay after elective primary total hip arthroplasty. Design: A search was conducted of the electronic databases MEDLINE, EMBASE and CINAHL from inception through April 2014. Observational studies were...
article 2015
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Wopereis, S. (author), Radonjic, M. (author), Rubingh, C. (author), van Erk, M. (author), Smilde, A. (author), van Duyvenvoorde, W. (author), Cnubben, N. (author), Kooistra, T. (author), van Ommen, B. (author), Kleemann, R. (author)
The prevalence of diabetes mellitus Type 2 could be significantly reduced by early identification of subjects at risk, allowing for better prevention and earlier treatment. Glucose intolerance (GI) is a hallmark of the prediabetic stage. This study aims at identifying 1) prognostic biomarkers predicting the risk of developing GI later in life...
article 2012
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Steevens, J. (author), Schouten, L.J. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author)
Prospective epidemiologic data on vegetables and fruits consumption and risk of subtypes of esophageal and gastric cancer are sparse. We studied the association between vegetables and fruits consumption and risk of esophageal squamous cell carcinoma (ESCC), esophageal adenocarcinoma (EAC), gastric cardia adenocarcinoma (GCA) and gastric...
article 2011
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Heymans, M.W. (author), van Buuren, S. (author), Knol, D.L. (author), Anema, J.R. (author), van Mechelen, W. (author), de Vet, H.C.W. (author), TNO Kwaliteit van Leven (author)
Background context: The recovery of patients with chronic low back pain (LBP) is slow. Furthermore, it is recently proposed that chronic LBP needs a prognostic approach to determine who will develop clinically significant back pain. Therefore, it is imperative to identify prognostic factors that are mostly seen in chronic LBP patients at an...
article 2010
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Offersen, B.V. (author), Knap, M.M. (author), Horsman, M.R. (author), Verheijen, J. (author), Hanemaaijer, R. (author), Overgaard, J. (author), TNO Kwaliteit van Leven (author)
Introduction. Matrix metalloproteinase 9 (MMP-9) is an endopeptidase involved in various cellular processes, such as tumour development and metastatic spread. In biological samples, MMP-9 can occur as pro-MMP-9 and active MMP-9, or these factors complexed with the inhibitor TIMP-1. An assay, which can measure active and total MMP-9 in biological...
article 2010
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van Spil, W.E. (author), de Groot, J. (author), Lems, W.F. (author), Oostveen, J.C.M. (author), Lafeber, F.P.J.G. (author), TNO Kwaliteit van Leven (author)
Context: Molecules that are released into biological fluids during matrix metabolism of articular cartilage, subchondral bone, and synovial tissue could serve as biochemical markers of the process of osteoarthritis (OA). Unfortunately, actual breakthroughs in the biochemical OA marker field are limited so far. Objective: By reviewing the status...
article 2010
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Ceconi, C. (author), Fox, K.M. (author), Remme, W.J. (author), Simoons, M.L. (author), Deckers, J.W. (author), Bertrand, M. (author), Parrinello, G. (author), Kluft, C. (author), Blann, A. (author), Cokkinos, D. (author), Ferrari, R. (author), TNO Kwaliteit van Leven (author)
The PERTINENT study measured biomarkers of atherosclerosis and thrombosis in a stable coronary artery disease population from EUROPA receiving ACE inhibition with perindopril 8 mg/day or placebo. Biomarkers of inflammation, C-reactive protein (CRP), fibrinogen, and tumor necrosis factor-alpha (TNF-α), and a biomarker of thrombosis, d-dimer, were...
article 2009
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van Spronsen, F.J. (author), Rijn, M. (author), Dorgelo, B. (author), Hoeksma, M. (author), Bosch, A.M. (author), Mulder, M.F. (author), de Klerk, J.B.C. (author), de Koning, T. (author), Rubio-Gozalbo, M.E. (author), de Vries, M. (author), Verkerk, P.H. (author)
Background: The clinical severity of phenylalanine hydroxylase deficiency is usually defined by either pre-treatment phenylalanine (Phe) concentration or Phe tolerance at 5 years of age. So far, little is known about the course of Phe tolerance or the ability of both pre-treatment Phe and Phe tolerance at early age to predict Phe tolerance at...
article 2009
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Blink, M. (author), Buitenkamp, T.D. (author), van Wouwe, J.P. (author), van Wering, E.R. (author), van der Velden, V.H.J. (author), Zwaan, C.M. (author), TNO Kwaliteit van Leven (author)
Children with Down syndrome (DS) have an increased risk for developing both acute myeloid as well as acute lymphoblastic leukemia. These leukemias differ in clinical characteristics and biology compared to leukemias in non-DS children. Moreover, children with DS have an increased risk of side-effects from cytostatic therapy, which complicates...
article 2009
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Pereira, R.R. (author), Draaisma, J.M.T. (author), TNO Kwaliteit van Leven (author)
article 2009
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Ketelslegers, I.A. (author), Boon, M. (author), Pereira, R.R. (author), Hintzen, R.Q. (author), Catsman-Berrevoets, C.E. (author), TNO Kwaliteit van Leven (author)
Acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS) in children are relatively rare and the exact incidence is still unknown. There is great variability in clinical presentation and disease course. It is yet unclear which clinical and biological parameters can predict a chronic disease course and progression to multiple...
article 2009
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Hellebrekers, B.W.J. (author), Trimbos-Kemper, T.C.M. (author), Boesten, L. (author), Jansen, F.W. (author), Kolkman, W. (author), Trimbos, J.B. (author), Press, R.R. (author), van Poelgeest, M.I.E. (author), Emeis, S.J. (author), Kooistra, T. (author), TNO Kwaliteit van Leven (author)
Objective: To identify predictors of postsurgical adhesion formation in peritoneal fluid and plasma, and assess efficacy and safety of reteplase (recombinant plasminogen activator [r-PA]). Design: Prospective randomized study. Setting: University Medical Center. Patient(s): Twenty-six abdominal myomectomy patients with early second-look...
article 2009
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TNO Kwaliteit van Leven (author), Perenboom, R.J.M. (author)
report 2009
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Geert Heidema, A. (author), Thissen, U. (author), Boer, J.M.A. (author), Bouwman, F.G. (author), Feskens, E.J.M. (author), Mariman, E.C.M. (author), TNO Kwaliteit van Leven (author)
In this study, we applied the multivariate statistical tool Partial Least Squares (PLS) to analyze the relative importance of 83 plasma proteins in relation to coronary heart disease (CHD) mortality and the intermediate end points body mass index, HDL-cholesterol and total cholesterol. From a Dutch monitoring project for cardiovascular disease...
article 2009
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Hack, W.M. (author), Goede, J. (author), Pierik, F.H. (author), Sijstermans, K. (author), TNO Bouw en Ondergrond (author)
article 2008
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Stern, R. (author), Builtjes, P. (author), Schaap, M. (author), Timmermans, R. (author), Vautard, R. (author), Hodzic, A. (author), Memmesheimer, M. (author), Feldmann, H. (author), Renner, E. (author), Wolke, R. (author), Kerschbaumer, A. (author), TNO Bouw en Ondergrond (author)
Five three-dimensional chemical transport models of different complexity were applied to Central Europe to assess the ability of models to reproduce PM10 concentrations under highly polluted conditions. The participating models were the French CHIMERE model, the Dutch LOTOS-EUROS model, as well as the REM-CALGRID, the EURAD and the LM-MUSCAT...
article 2008
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Balk, A.H. (author), Davidse, W. (author), van Dommelen, P. (author), Klaassen, E. (author), Caliskan, K. (author), van der Burgh, P. (author), Leenders, C.M. (author), TNO Kwaliteit van Leven (author), KvL (author)
Background: New strategies are required to optimize care in increasing numbers of chronic heart failure patients. The aim of this randomised trial was to evaluate a remote guidance system. Methods: Intervention group patients received a home TV-channel providing educational materials. Tele-guidance was performed by a Medical Service Centre....
article 2008
Searched for: subject%3A%22Prognosis%22
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