Laboratory- to Pilot-Scale Fractionation of Lignocellulosic Biomass Using an Acetone Organosolv Process

Acetone organosolv fractionation of beech and birch wood at the lab-scale results in high sugar yields from the (hemi)cellulose and the isolation of a high-purity lignin. In this study, the process is scaled up to validate the technology at the pilot scale using industrial-size beech and birch wood chips and low liquid-to-solid ratios as a next...

CFD analysis and flow model reduction for surfactant production in helix reactor = CFD analiza i redukcija modela strujanja za proizvodnju surfaktanta u helix reaktoru

Flow pattern analysis in a spiral Helix reactor is conducted, for the application in commercial surfactant production. Step change response curves (SCR) were obtained from numerical tracer experiments by three-dimensional computational fluid dynamics (CFD) simulations. Non-reactive flow is simulated, though viscosity is treated as variable in...

One solution fits all?: A need for the benchmarking of continuous process technologies

Whilst continuous processing is a mainstream technique in the petrochemical and food industries as a tool for accessing highly productive and low cost production processes, until recently the pharmaceutical, fine chemical and specialty chemical industries were still dominated by batch processes and segmented unit operations. Through multi...

Reactor comparison for the esterification of fatty acids from waste cooking oil

Esterification of the fatty acids contained in waste cooking oil with glycerol, a reaction involving immiscible and viscous reactants, was achieved in two pilot-scale continuous pulsed reactors: the oscillatory baffled reactor and the helix reactor. In both reactors, with or without baffles, the reaction reaches its thermodynamic equilibrium at...

Concomitant crystallization for in situ encapsulation of organic materials

Concomitant crystallization leads to process intensification through the synergistic combination of the partial processes of particle formation and encapsulation within a single process step. Both cooling and electrospray crystallization in multi-component solutions were used to create (sub-)micron sized particles of different crystalline...

CFD analysis and flow model reduction for surfactant production in helix reactor

Flow pattern analysis in a spiral Helix reactor is conducted, for the application in the commercial surfactant production. Step change response curves (SCR) were obtained from numerical tracer experiments by three-dimensional computational fluid dynamics (CFD) simulations. Non-reactive flow is simulated, though viscosity is treated as variable...

Nanoparticle generation by intensified solution crystallization using cold plasma

In this study, atmospheric pressure cold plasma (surface dielectric barrier discharge) was used as an alternative energy form to intensify solution crystallization and produce nano-sized organic crystals. Nano-sized particles can have beneficial product properties such as improved internal quality and dissolution rate, compared to conventionally...

Process intensification in crystallization: Submicron particle generation using alternative energy forms

Crystallization is one of the oldest separation and product formation techniques that continues to be in use today. Despite its long history, it only started to develop significantly in the past few decades. In this thesis, the application of Process Intensification in crystallization is investigated. Process Intensification is a set of often...

Helix reactor: great potential for flow chemistry

The Helix reactor is highly suited for precise reaction control based on good hydrodynamics. The hydrodynamics are controlled by the Dean vortices, which create excellent heat transfer properties, approach plug flow and avoid turbulence. The flexibility of this reactor has been demonstrated using a very exothermic, temperature sensitive...

TNO's work on intensification; practical examples

TNO, a Dutch organisation for contract research, is and has been involved in numerous process intensification projects in close collaboration with national and international process industries. TNO has different facilities available to fulfil the demands for intensification projects. Depending on the focus of a project, a multidisciplinary team...