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Joosten, M.M. (author), Schrieks, I.C. (author), Hendriks, H.F.J. (author)Background: Fetuin-A, a liver-derived glycoprotein that impairs insulin-signalling, has emerged as a biomarker for diabetes risk. Although moderate alcohol consumption has been inversely associated with fetuin-A, data from clinical trials are lacking. Thus, we evaluated whether moderate alcohol consumption decreases circulating levels of fetuin...article 2014
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Schouten, L.J. (author), Rivera, C. (author), Hunter, D.J. (author), Spiegelman, D. (author), Adami, H.-O. (author), Arslan, A. (author), Beeson, W.L. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Folsom, A.R. (author), Fraser, G.E. (author), Freudenheim, J.L. (author), Goldbohm, R.A. (author), Hankinson, S.E. (author), Lacey Jr., J.V. (author), Leitzmann, M. (author), Lukanova, A. (author), Marshall, J.R. (author), Miller, A.B. (author), Patel, A.V. (author), Rodriguez, C. (author), Rohan, T.E. (author), Ross, J.A. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)Background: Although many studies have investigated the association between anthropometry and ovarian cancer risk, results have been inconsistent. Methods: The associations of height, body mass index (BMI), and ovarian cancer risk were examined in a pooled analysis of primary data from 12 prospective cohort studies from North America and Europe....article 2008
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van den Brandt, P.A. (author), Spiegelman, D. (author), Yaun, S-S. (author), Adami, H-O. (author), Beeson, L. (author), Folsom, A.R. (author), Fraser, G. (author), Goldbohm, R.A. (author), Graham, S. (author), Kushi, L. (author), Marshall, J.R. (author), Miller, A.B. (author), Rohan, T. (author), Smith-Warner, S.A. (author), Speizer, F.E. (author), Willett, W.C. (author), Wolk, A. (author), Hunter, D.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)The association between anthropometric indices and the risk of breast cancer was analyzed using pooled data from seven prospective cohort studies. Together, these cohorts comprise 337,819 women and 4,385 incident invasive breast cancer cases. In multivariate analyses controlling for reproductive, dietary, and other risk factors, the pooled...article 2000
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Relationship between visceral fat and PAI-1 in overweight men and women before and after weight lossKockx, M. (author), Leenen, R. (author), Seidell, J. (author), Princen, H.M.G. (author), Kooistra, T. (author), Gaubius instituut TNO (author)This study was aimed at evaluating the relationship between visceral fat accumulation and plasma plasminogen activator inhibitor-1 (PAI-1) levels in healthy, obese men and women undergoing weight loss therapy. The subjects, 25 men and 25 premenopausal women, aged between 26 and 49 years, with an initial body mass index between 28 and 38 kg/m2,...article 1999