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TNO Defensie en Veiligheid (author), Langenberg, J.P. (author), van der Schans, M.J. (author), Noort, D. (author)The perceived threat of the use of nerve agents by terrorists against civilian targets implies the need for methods for point-of-care (POC) diagnosis. This review presents an overview of methods that are currently available for the assessment of exposure to nerve agents. Since these methods are mostly MS based, they require complex and expensive...article 2009
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van Groenestijn, J.W. (author), Geelhoed, J.S. (author), Goorissen, H.P. (author), Meesters, K.P.M. (author), Stams, A.J.M. (author), Claassen, P.A.M. (author), TNO Kwaliteit van Leven (author)Non-axenic operation of a 400 L trickle bed reactor inoculated with the thermophile Caldicellulosiruptor saccharolyticus, yielded 2.8 molH 2mol hexose converted. The reactor was fed with a complex medium with sucrose as the main substrate, continuously flushed with nitrogen gas, and operated at 73°C. The volumetric productivity was 22 mmolH2(L...article 2009
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TNO Defensie en Veiligheid (author), Dijk, J. (author), van Eekeren, A.W.M. (author), Schutte, K. (author), de Lange, D.J.J. (author), van Vliet, L.J. (author)When bright moving objects are viewed with an electro-optical system at very long range, they will appear as small slightly blurred moving points in the recorded image sequence. Detection of point targets is seriously hampered by structure in the background, temporal noise and aliasing artifacts due to undersampling by the infrared (IR) sensor....conference paper 2009
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Fischer, H.R. (author), TNO Industrie en Techniek (author)Micro-thermal analysis (μTATM) is a technique in which thermal analysis is performed on surfaces of test specimens on a small (ca. 2×2 μm) scale. Like any thermal analysis technique, interpretation of results benefits from accurate temperature information and knowledge of the precision of the resultant measurement. However, temperature...article 2008
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TNO Defensie en Veiligheid (author), Dijk, J. (author), van Eekeren, A.W.M. (author), Schutte, K. (author), de Lange, D.J.J. (author), van Vliet, L.J. (author)When bright moving objects are viewed with an electrooptical system at long range, they appear as small, slightly blurred moving points in the recorded image sequence. Typically, such point targets need to be detected in an early stage. However, in some scenarios the background of a scene may contain much structure, which makes it difficult to...article 2008
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TNO Bouw en Ondergrond (author), Callaghan, A. (author), de Leeuw, G. (author), Cohen, L. (author), O'Dowd, C.D. (author)Sea surface images obtained during the 2006 Marine Aerosol Production (MAP) campaign in the North East Atlantic were analysed for values of percentage whitecap coverage (W). Values of W are presented for wind speeds up to circa 23 m s-1. The W data were divided into two overlapping groups and a piecewise, wind-speed-only parameterization of W is...article 2008
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Trottemant, E.J. (author), Vermeulen, A. (author), Weiss, M. (author), TNO Defensie en Veiligheid (author)New developments and improvements on evasive missiles have led to a situation in which the current missile guidance laws have difficulties to intercept maneuvering targets. The nature of the interception problem with 2 non-cooperative players leads to the field of differential games. Recent studies have focused on the so-called zero-sum Nash...conference paper 2007
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Cremers, A.H.M. (author), Kuijper, I. (author), Groenewegen, P.L.M. (author), Post, W.M. (author), TNO Defensie en Veiligheid (author)The objective of our study was to design and evaluate a user interface concept for a so-called Project Browser, following a user-centered design method. Previous work has suggested that users prefer to access project-related information instrumental to the task they have to carry out. First, a domain analysis was carried out, followed by an...conference paper 2007
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Cremers, A.H.M. (author), Kuiper, I. (author), Groenewegen, P. (author), Post, W.M. (author), TNO Defensie en Veiligheid (author)Abstract. The objective of our study was to design and evaluate a user interface concept for a so-called Project Browser, following a user-centered design method. Previous work has suggested that users prefer to access project-related information instrumental to the task they have to carry out. First, a domain analysis was carried out, followed...conference paper 2007
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Energieonderzoek Centrum Nederland (author), Bonekamp, B.C. (author), Correia, L.A. (author), va. Horssen, A. (author)The key factor in obtaining defect free macroporous membrane supports is found in the application of multiple inorganic suspension coatings rather than the use of a single somewhat thicker macroporous layer. Colloidal processing plays an important role in achieving such a multiple layer system. Finding the optimal coating conditions is, however,...conference paper 2007
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Bonekamp, B.C. (author), Haije, W.G. (author), Correia, L.A. (author), Vente, J.F. (author), va. Horssen, A. (author)Bubble number porometry and Hg porosimetry were used to investigate the density and size of percolating channels in gross macroporous support tubes, support tubes coated with one or two macroporous gamma-alumina layers and the latter coated with a thin mesoporous gamma-alumina layer. The key factor in obtaining macroporous thin layers with bulk...article 2007
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TNO Kwaliteit van Leven (author), van der Horst, M.A. (author), Arents, J.C. (author), Kort, R. (author), Hellingwerf, K.J. (author)The bacterial photoreceptor protein photoactive yellow protein (PYP) covalently binds the chromophore 4-hydroxy coumaric acid, tuning (spectral) characteristics of this cofactor. Here, we study this binding and tuning using a combination of pointmutations and chromophore analogs. In all photosensor proteins studied to date the covalent linkage...article 2007
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TNO Defensie en Veiligheid (author), de Lange, D.J.J. (author), Dijk, J. (author), van Eekeren, A.W.M. (author), Schutte, K. (author)Surveillance applications are primarily concerned with detection of targets. In electro-optical surveillance systems, missiles or other weapons coming towards you are observed as moving points. Typically, such moving targets need to be detected in a very short time. One of the problems is that the targets will have a low signal-to-noise ratio...conference paper 2007
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Gray, S.L. (author), Dalla Nora, E. (author), Grosse, J. (author), Manieri, M. (author), Stoeger, T. (author), Medina-Gomez, G. (author), Burling, K. (author), Wattler, S. (author), Russ, A. (author), Yeo, G.S.H. (author), Chatterjee, V.K. (author), O'Rahilly, S. (author), Voshol, P.J. (author), Cinti, S. (author), Vidal-Puig, A. (author), TNO Preventie en Gezondheid (author)Peroxisome proliferator-activated receptor (PPAR)γ is a key transcription factor facilitating fat deposition in adipose tissue through its proadipogenic and lipogenic actions. Human patients with dominant-negative mutations in PPARγ display lipodystrophy and extreme insulin resistance. For this reason it was completely unexpected that mice...article 2006
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van der Schaaf, J. (author), Beerkens, R.G.C. (author), TNO Industrie en Techniek (author)A dynamic model for describing the build-up and breakdown of a glass-melt foam is presented. The foam height is determined by the gas flux to the glass-melt surface and the drainage rate of the liquid lamellae between the gas bubbles. The drainage rate is determined by the average gas bubble radius and the physical properties of the glass melt:...article 2006
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Ham, J.M. (author), Meulenbrugge, J.J. (author), Versloot, N.H.A. (author), Dechy, N. (author), Lecoze, J.-C. (author), Salvi, O. (author), TNO Bouw en Ondergrond TNO Defensie en Veiligheid (author)The SEVESO II directive has created a common framework for the European state members for the implementation of risk management strategies that require the introduction of various dimensions ranging from technical to organisational ones. Local regulations in countries have however diverse histories and philosophies. Some regulations include the...conference paper 2006
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Welland, W.H.M. (author), Cianfanelli, S. (author), van der Heijden, A.E.D.M. (author), Leeming, W. (author), TNO Defensie en Veiligheid (author)In this paper, recent activities on the development of Hydrazinium Nitroformate (HNF) and HNF based propellants are discussed from different perspectives -programmatic, technical, and strategic. From a programmatic point of view, the current programmes on HNF and their goals are discussed in relation to the Milestone Decision Points that have...conference paper 2006
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Liebsch, M. (author), Spielmann, H. (author), Pape, W. (author), Krul, C. (author), Deguercy, A. (author), Eskes, C.A.M. (author), TNO Kwaliteit van Leven (author)Regulatory requirements: According to the current Notes for Guidance of the Scientific Committee on Cosmetic Products and Non-Food Products (SCCNFP), cosmetic ingredients and mixtures of ingredients absorbing UV light (in particular UV filter chemicals used, for example, to ensure the light stability of cosmetics or used in sun protection...article 2005
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Zhu, Q. (author), de With, G. (author), Dortmans, L.J.M.G. (author), Feenstra, F. (author), TNO Industrie (author)Near net-shape fabrication of hydroxyapatite (HA) glass composites has been attempted by infiltrating a glass into porous HA performs. Main efforts were put to develop glasses that are chemically compatible with HA at elevated temperatures. After extensive investigations in the phosphate and borosilicate systems, glasses of (50-55)SiO2-(20-25...article 2004
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van Hoof, J.F.A.M. (author), van Markwijk, R. (author), Verver, M.M. (author), Furtado, R. (author), Pewinsky, W. (author), TNO Wegtransportmiddelen (author)Two of the main design objectives for car interiors are comfort and safety. These aspects are both determined by the seating position of the occupant. Seat manufacturers use the SAE Three-Dimensional H-Point Machine™ to measure seating positions to design, audit, and benchmark seats. The seating positions measured with the H-Point Machine form...conference paper 2004