Searched for: subject%3A%22Peak%255C%2Bexposure%22
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document
Meijster, T. (author), Tielemans, E. (author), Schinkel, J. (author), Heederik, D. (author), TNO Kwaliteit van Leven (author)
Objectives: To effectively decrease occupational exposure to flour dust and related allergens, detailed information on exposure determinants and effectiveness of control measures is essential. In this paper, we use personal real-time exposure measurements to get more insight into the relationship between specific work characteristics, including...
article 2008
document
Lammers, J.H.C.M. (author), Meuling, W.J.A. (author), Muijser, H. (author), Freidig, A.P. (author), Bessems, J.G.M. (author), TNO Kwaliteit van Leven (author)
The health risks of inhalation exposure to volatile organic solvents may not only depend on the total external dose, but also on the pattern of exposure. It has been suggested that exposure to regularly occurring peak concentrations may have a stronger impact on the brain than constant exposure at the same average level. Recent animal...
article 2005
document
Lammers, J.H.C.M. (author), van Asperen, J. (author), de Groot, D. (author), Rijcken, W.R.P. (author), TNO Kwaliteit van Leven (author)
The toxicity of exposure by inhalation to organic solvents may not only be related to the total external dose, but also to the pattern of exposure. In this study the impact of the exposure scenario on the behavioural effects of the model solvent toluene in rats was investigated. Rats were exposed for 7.5 h to either a constant concentration or...
article 2005
document
van Asperen, J. (author), Rijcken, W.R.P. (author), Lammers, J.H.C.M. (author), TNO Voeding (author)
The toxicity of inhalatory exposure to organic solvents may not only be related to the total external dose, but also to the pattern of exposure. In this study physiologically based toxicokinetic (PBTK) modelling has been used to study the impact of the exposure scenario on the toxicokinetics and the behavioural effects of the model solvent...
article 2003
Searched for: subject%3A%22Peak%255C%2Bexposure%22
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