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Bos, W.J.W. (author), Zietse, R. (author), Wesseling, K.H. (author), Westerhof, N. (author), TNO Biomedical Instrumentation (author)Background. Arteriovenous (AV) fistulas used for hemodialysis access may affect cardiac load by increasing the preload while decreasing the afterload. In dogs, AV fistulas have also been shown to affect coronary perfusion negatively. We investigated the net effect of AV fistulas on cardiac oxygen supply and demand. Methods. Aortic pressure waves...article 1999
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Kant, A.R. (author), Tuinenburg, C. (author), Hellkamp, U. (author), TNO Wegtransportmiddelen (author)The numerical optimisation of the thorax & head dual cavity side airbag has been an integrated part of a thorax & head feasibility study for a mid size vehicle. The objective was to minimise injury parameters for the EUROSID-1 due to a side impact deformable barrier crash test. To reach this objective, the distribution of gas between the...conference paper 1998
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Lourenço, P.B. (author), Rots, J.G. (author), Blaauwendraad, J. (author), TNO Bouw (author)A novel yield criterion that includes different strengths along each material axis is presented. The criterion includes two different fracture energies in tension and two different fracture energies in compression. The ability of the model to represent the inelastic behavior of orthotropic materials is shown, and a set of experimental tests to...article 1998
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TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author), Ploemen, J.P.H.T.M. (author), Wormhoudt, L.W. (author), Haenen, G.R.M.M. (author), Oudshoorn, M.J. (author), Commandeur, J.N.M. (author), Vermeulen, N.P.E. (author), de Waziers, I. (author), Beaune, P.H. (author), Watabe, T. (author), van Bladeren, P.J. (author)Ethylene dibromide (1,2-dibromoethane, EDB) is metabolized by two routes: a conjugative route catalyzed by glutathione S-transferases (GST) and an oxidative route catalyzed by cytochrome P450 (P450). The GST route is associated with carcinogenicity. An approach is presented to use human purified GST and P450 enzymes to explore the importance of...article 1997
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te Velthuis - Wierik, E.J.M. (author), Kluft, C. (author), van den Berg, H. (author), Weststrate, J.A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)A high fat intake has been associated with the high prevalence of coronary heart disease (CHD) in most Western countries. Consumption of reduced-fat products might reduce fat intake and beneficially affect markers of CHD risk. Therefore, the effects of 6 months of realistic consumption of reduced-fat products on energy and fat intake,...article 1996
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de Maat, M.P.M. (author), de Bart, A.C.W. (author), Hennis, B.C. (author), Meijer, P. (author), Havelaar, A.C. (author), Mulder, P.G.H. (author), Kluft, C. (author), Gaubius Instituut TNO (author)We compared intraindividual and interindividual variability in the plasma levels of fibrinogen, tissue-type plasminogen activator (TPA) antigen, plasminogen activator inhibitor (PAI) activity, and C-reactive protein (CRP) in 20 healthy, young individuals and 26 patients with stable angina pectoris (AP) who were at higher risk for cardiovascular...article 1996
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de Kroon, M. (author), Driessen, F. (author), Technisch Physische Dienst TNO - TH (author)A Figure-of-Merit for the performance of any medical array is defined, which is new in the field of medical imaging: the object contrast parameter. This contrast parameter quantifies the contrast between an on-axis object and its surroundings and as such is closely related to the visibility of an object. Its behaviour as a function of depth...conference paper 1996
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Janssens, M.H.A. (author), Thompson, D.J. (author), Technisch Physische Dienst TNO - TH (author)The sound level of a train crossing a steel railway bridge is usually about 10 dB higher than on plain track. In the Netherlands there are many such bridges which, for practical reasons, cannot be replaced by more intrinsically quiet concrete bridges. A computational model is described for the estimation of noise levels due to a train crossing a...article 1996
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Vink, P. (author), Bots, T.L. (author), TNO Industrie (author)Research was carried out aimed at the development of self-stratifying paints for steel which after application during film formation spontaneously form two well established layers of primer and top coat. The parameters affecting stratification were investigated for combinations of epoxy resins and physically drying binders. Incompatibility of...article 1996
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Burgmeijer, R.J.F. (author), de Jonge, G.A. (author), TNO Preventie en Gezondheid (author)Objective: To determine whether the sleeping position and the use of duvets in infants in 1994 had changed in comparison with earlier years. Design: Questionnaire survey. Setting: Nationwide investigation in infant welfare centres. Method: 194 infant welfare centres participated in the investigation. In November a questionnaire was completed...article 1995
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Grootenhuis, P.A. (author), Westenbrink, S. (author), Sie, C.M.T.L. (author), de Neeling, J.N.D. (author), Kok, F.J. (author), Bouter, L.M. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)A self-administered semiquantitative food frequency questionnaire including 75 food items and providing information on the habitual intake of 31 nutritional parameters, based on the intake of protein, fat, carbohydrate, fiber and 11 vitamins and minerals, was developed for use in epidemiologic research on chronic disease among the elderly, such...article 1995
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Papp, Z. (author), Driessen, B.J.F. (author), Technisch Physische Dienst TNO - TH (author)The paper presents an adaptive nonlinear (state-) feedback control structure, where the nonlinearities are implemented as smooth fuzzy mappings defined as rule sets. The fine tuning and adaption of the controller is realized by an indirect adaptive scheme, which modifies the parameters of the fuzzy mapping. The performance index gradients are...conference paper 1995
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van Oosten, J.J.M. (author), Bakker, E. (author), TNO Wegtransportmiddelen (author)Tyre behaviour plays an important role in vehicle dynamics studies. The Magic Formula Tyre Model is a semi-empirical tyre model which can describe tyre behaviour quite accurately. A set of Magic Formula parameters constitutes the basis of the model. The determination of these parameters out of tyre measurement data produced by the Delft tyre...article 1991
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van Dijk, H.A.L. (author), Kratz, P. (author), Technisch Physische Dienst TNO - TH (author)Eén van de aktiviteiten van de Technisch Physische Dienst (TPD) van TNO op het gebied van onderzoek naar de thermische benutting van zonne-energie betreft het beproeven van uiteenlopende soorten van voorzieningen voor de tijdelijke opslag van de ingevangen zonnewarmte. In de loop der jaren groeide de behoefte om de opgedane ervaringen op dit...article 1987