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Johnson, D. (author), Carter, M.D. (author), Crow, B.S. (author), Isenberg, S.L. (author), Graham, L.A. (author), Erol, H.A. (author), Watson, C.M. (author), Pantazides, B.G. (author), van der Schans, M.J. (author), Langenberg, J.P. (author), Noort, D. (author), Blake, T.A. (author), Thomas, J.D. (author), Johnson, R.C. (author)Tri-ortho-cresyl phosphate (ToCP) is an anti-wear, flame retardant additive used in industrial lubricants, hydraulic fluids and gasoline. The neurotoxic effects of ToCP arise from the liver-activated metabolite 2-(o-cresyl)-4H-1,3,2-benzodioxaphosphoran-2-one (cresyl saligenin phosphate or CBDP), which inhibits esterase enzymes including...article 2015
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van der Linde-Sipman, J.S. (author), van den Inch, T.S.G.A.M. (author), van Nes, J.J. (author), Verhagen, H. (author), Kersten, J.G.T.M. (author), Beynen, A.C. (author), Plekkringa, R. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)In April 1996, an outbreak of toxic polyneuropathy in cats occurred in the Netherlands. All cats had been fed one of two brands of dry cat food from one manufacturer. Chemical analyses of these foods, stomach contents, and liver and kidney of affected cats revealed contamination with the ionophor salinomycin. Epidemiologic and clinical data were...article 1999
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Oostvogel, P.M. (author), van Conyn-Spaendonck, M.A.E. (author), Hirasing, R.A. (author), van Loon, A.M. (author), TNO Preventie en Gezondheid (author)Detection and investigation of call cases of acute flaccid paralysis (AFP) in children below 15 years of age are among the criteria for poliomyelitis-free certification. In the absence of poliomyelitis the incidence of AFP is around 1 per 100 000 children aged < 15 years. In the Netherlands, surveillance of AFP began in October 1992 under the...article 1998
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- Oostvogel, P.M. (author), van Conyn-Spaendonck, M.A.E. (author), Hirasing, R.A. (author), van Loon, A.M. (author), TNO Preventie en Gezondheid (author) report 1996