Conductivity Enhancement of Binder-Based Graphene Inks by Photonic Annealing and Subsequent Compression Rolling

This paper describes a combination of photonic annealing and compression rolling to improve the conductive properties of printed binder-based graphene inks. High-density light pulses result in temperatures up to 500 °C that along with a decrease of resistivity lead to layer expansion. The structural integrity of the printed layers is restored...

PET-CT imaging with [18F]-gefitinib to measure Abcb1a/1b (P-gp) and Abcg2 (Bcrp1) mediated drug-drug interactions at the murine blood-brain barrier

Introduction: The efflux transporters P-glycoprotein (P-gp, ABCB1) and breast cancer resistance protein (BCRP, ABCG2) are expressed at the blood-brain barrier (BBB), and can limit the access of a wide range of drugs to the brain. In this study we developed a PET-CT imaging method for non-invasive, quantitative analysis of the effect of ABCB1 and...

The ultimate radiochemical nightmare: Upon radio-iodination of Botulinum neurotoxin A, the introduced iodine atom itself seems to be fatal for the bioactivity of this macromolecule

Background: Botulinum neurotoxin A (BoNT-A) is a highly neurotoxic drug and frequently used in patients. Knowledge on the optimal way of administration of BoNT-A and its subsequent distribution is still rather limited. An accurate method for monitoring these processes might be the use of radiolabelled BoNT-A. In this paper, we report our...

PET imaging of disease progression and treatment effects in the experimental autoimmune encephalomyelitis rat model

The experimental autoimmune encephalomyelitis model is a model of multiple sclerosis that closely mimics the disease characteristics in humans. The main hallmarks of multiple sclerosis are neuroinflammation (microglia activation, monocyte invasion, and T-cell infiltration) and demyelination. PET imaging may be a useful noninvasive technique for...

High curvature bending characterization of ultra-thin chips and chip-on-foil assemblies

Ultra-thin chips of less than 20μm become flexible, allowing integration of silicon IC technology with highly flexible electronics. This combination allows for highly intelligent products of unprecedented thinness, flexibility and cost. Examples include sensor systems integrated into food packaging or healthcare and sport monitoring tags as...

Requirements for multimedia metadata schemes in surveillance applications for security

Surveillance for security requires communication between systems and humans, involves behavioural and multimedia research, and demands an objective benchmarking for the performance of system components.Metadata representation schemes are extremely important to facilitate (system) interoperability and to define ground truth annotations for...

Delay and impairment in brain development and function in rat offspring after maternal exposure to methylmercury

Maternal exposure to the neurotoxin methylmercury (MeHg) has been shown to have adverse effects on neural development of the offspring in man. Little is known about the underlying mechanisms by which MeHg affects the developing brain. To explore the neurodevelopmental defects and the underlying mechanism associated with MeHg exposure, the...

Automated synthesis of [18F]gefitinib on a modular system

In recent years, [ 18F]gefitinib PET has successfully been employed for a number of applications ranging from oncology to in vivo studies of drug transporter proteins. We here report a reliable, automated procedure for routine synthesis of this radiotracer on an Eckert and Ziegler modular system. The 3-step radiosynthesis followed by preparative...

Flipchip bonding of thin Si dies onto PET foils: Possibilities and applications

Low cost large area flexible electronic products are expected to be used in a wide range of applications and in large quantities in our society. Examples of this include sensor packages added to food or conformal intelligent patches that monitor a patient's well-being. Because of their large area, the preferred substrate material for these...

The influence of surface DBD plasma treatment on the adhesion of coatings to high-tech textiles

The surface of high-performance poly(ethylene terephthalate) (PET) fibers is difficult to wet and impossible to chemically bond to different matrices. Sizing applied on the fiber surface usually improves fiber wetting, but prevents good adhesion between a matrix and the fiber surface. The present study demonstrates that the plasma treatment...

Effect of package light transmittance on the vitamin content of milk, part 3: Fortified UHT low-fat milk

This work is the third and last part of a milk study evaluating the effect of package light transmittance on the vitamin content of milk, in this case on fortified UHT low-fat milk. The milk was stored under light with an intensity of 700 lux in polyethylene terephthalate (PET) bottles with varying light transmittance to monitor the changes in...

A comparative study of via drilling and scribing on PEN and PET substrates for flexible electronic applications using excimer and Nd:YAG laser sources

A study on via drilling and channel scribing on PEN and PET substrates for flexible electronic application is discussed in this paper. For the experiments, both KIF excimer laser (248 nm) and frequency tripled Nd:YAG (355 nm) laser are used. Different measurement techniques like optical microscopy, Dektak profilometer, Confocal microscopy and...

Quality and safety aspects of reusable plastic food packaging materials: Influence of reuse on intrinsic properties

The aim of the project was to develop a comprehensive package of quality assurance criteria for use by the industry and by regulatory authorities to ensure the quality and safety-in-use (sensory, microbiological and chemical safety) of reused plastics for food packaging. The paper describes the investigations into potential adulteration effects...

Quality and safety aspects of reusable plastic food packaging materials: A European study to underpin future legislation

The objective of this study was to develop a comprehensive package of quality assurance criteria for use by industry and regulatory authorities for ensuring the quality and safety-in-use (sensory, microbiological and chemical) of reused plastics for food packaging. The study included thermal degradation effects, flavour carry-over caused by...

Absorption of methanol and toluene by polyster-based bottles

Absorption aspects of flavours and chemicals are important quality criteria when plastic bottles are reused or recycled. In the present study absorption of methanol and toluene by polyester-based bottles (PET and PEN) was studied at different temperatures in the range 20-40°C for a period of 16 weeks with two different ways of exposure: one...

Polyethylene terephthalate bottles (PRBs): A health and safety assessment

As part of a multi-client project, the potential public health risks of the reuse of polyethylene terephthalate (PET) refillable bottles (PRBs) following possible misuse has been investigated. Participants in the project provided data and information from previous studies conducted independently at contract laboratories. These studies were...