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van Wijk, R. (author), van Wijk, E.P.A. (author), van Wietmarschen, H.A. (author), van der Greef, J. (author)For decades, the relationship between ultra-weak photon emission (UPE) and the health state of the body is being studied. With the advent of systems biology, attention shifted from the association between UPE and reactive oxygen species towards UPE as a reflection of changed metabolic networks. Essential for this shift in thinking is the...article 2014
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Yang, A. (author), Jedynska, A. (author), Hellack, B. (author), Kooter, I. (author), Hoek, G. (author), Brunekreef, B. (author), Kuhlbusch, T.A.J. (author), Cassee, F.R. (author), Janssen, N.A.H. (author)The capacity of Particulate Matter (PM) to oxidise target molecules, defined as its oxidative potential (OP), has been proposed as a biologically more relevant metric than PM mass. Different assays exist for measuring OP and their methodologies vary in the choice of extraction solvent and filter type. Little is known about the impact of...article 2014
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Boon, M.R. (author), Kooijman, S. (author), van Dam, A.D. (author), Pelgrom, L.R. (author), Berbée, J.F.P. (author), Visseren, C.A.R. (author), van Aggele, R.C. (author), van den Hoek, A.M. (author), Sips, H.C.M. (author), Lombès, M. (author), Havekes, L.M. (author), Tamsma, J.T. (author), Guigas, B. (author), Meijer, O.C. (author), Jukema, J.W. (author), Rensen, P.C.N. (author)The endocannabinoid system is an important player in energy metabolism by regulating appetite, lipolysis, and energy expenditure. Chronic blockade of the cannabinoid 1 receptor (CB1R) leads to long-term maintenance of weight loss and reduction of dyslipidemia in experimental and human obesity. The molecular mechanism by which CB1R blockade...article 2014
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Kim, E.S. (author), Cha, Y. (author), Ham, M. (author), Jung, J. (author), Kim, S.G. (author), Hwang, S. (author), Kleemann, R. (author), Moon, A. (author)A crucial role of the inflammatory lipid sphingosine-1-phosphate (S1P) in breast cancer aggressiveness has been reported. Recent clinical studies have suggested that C-reactive protein (CRP) has a role in breast cancer development. However, limited information is available on the molecular basis for the expression of CRP and its functional...article 2014
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Heyer, A. (author), D'Souza, F. (author), Morales, C.F.L. (author), Ferrari, G. (author), Mol, J.M.C. (author), de Wit, J.H.W. (author)Microbiologically Influenced Corrosion (MIC) is the term used for the phenomenon in which corrosion is initiated and/or accelerated by the activities of microorganisms. MIC is a very serious problem for the ship industry as it reduces structural lifetime in combination with safety risks for crewmembers or inspection personal and increases...article 2013
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Li, A. (author), Pfelzer, N. (author), Zuijderwijk, R. (author), Brickwedde, A. (author), van Zeijl, C. (author), Punt, P. (author)Aspergillus niger has an extraordinary potential to produce organic acids as proven by its application in industrial citric acid production. Previously, it was shown that expression of the cis-aconitate decarboxylase gene (cadA) from Aspergillus terreus converted A. niger into an itaconic acid producer (Li et al., Fungal Genet Bio 48: 602-611,...article 2013
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Daanen, H.A.M. (author), van Ling, S. (author), Tan, T.K. (author)Background: It has been shown that endurance performance after one night of sleep deprivation is not compromised despite the feeling of fatigue and that, in contrast, performance in the heat deteriorates even though people may feel good. However, it is essentially unknown how the estimation of performance capabilities relate to actual...article 2013
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Schreinemakers, J.R.C. (author), Oudenhuijzen, A.J.K. (author), van Amerongen, P.C.G.M. (author), Kon, M. (author)Background: The majority of Dutch F-16 pilots experience in-flight oxygen mask related nasal discomfort and injury. We aimed to analyze the fit of the oxygen mask. Methods: We successfully scanned 35 pilots with a 3D scanner to measure the distance between the contact area on the nose and the oxygen mask in seven points, and the difference (Δ)...article 2013
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Kimball, E. (author), Lambert, A. (author), Fossdal, A. (author), Leenman, R.N. (author), Comte, E. (author), van den Bos, W.A.P. (author), Blom, R. (author)The physio-chemical stability of the oxygen carrier material during chemical looping combustion (CLC) operation is crucial. In the present paper we discuss the challenges connected to operating a metal oxide base material in a cyclic manner between oxidizing and reducing atmospheres. Especially, focus has been put on the phase changes occurring...article 2013
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Daanen, H.A.M. (author), Lamberts, R.P. (author), Kallen, V.L. (author), Jin, A. (author), Meeteren, N.L.U. (author)Heart-rate recovery (HRR) has been proposed as a marker of autonomic function and training status in athletes. The authors performed a systematic review of studies that examined HRR after training. Five cross-sectional studies and 8 studies investigating changes over time (longitudinal) met our criteria. Three out of 5 cross-sectional studies...article 2012
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van Kersbergen, M.J. (author), Beerkens, R.G.C. (author), Sarmiento-Darkin, W. (author), Kobayashi, H. (author)The energy efficiency performance, production stability and emissions of oxygen-fired glass furnaces are influenced by the type of burner, burner nozzle sizes, burner positions, burner settings, oxygen-gas ratios and the fuel distribution among all the burners. These parameters have been optimized for a 300 tpd (metric tons per day glass pull)...conference paper 2012
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George, A. (author), Stawski, T.M. (author), Unnikrishnan, S. (author), Veldhuis, S.A. (author), ten Elshof, J.E. (author)A simple and cost effective methodology for large area micro and nanopatterning of a wide range of functional materials on flexible substrates is presented. A hydrophobic-hydrophilic chemical contrast was patterned on surfaces of various flexible plastic substrates using molds and shadow masks with which selected areas of the substrate surface...article 2012
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Koenen, M. (author), Tambach, T.J. (author), Neele, F.P. (author)In most cases, CO2 captured from power plants or large industrial sources contains impurities. As purification of the stream is energy and cost intensive it is necessary to allow a certain level of impurities. The effects of impurities on (short- and long-term) geological storage are, however, uncertain. In this work, geochemical modelling with...conference paper 2011
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van Wijk, E. (author), van der Greef, J. (author), van Wijk, R. (author)In the present experiment ultra-weak photon emission/ chemiluminescence from isolated neutrophils was recorded. It is associated with the production of reactive oxygen species (ROS) in the "respiratory burst" process which can be activated by PMA (Phorbol 12-Myristate 13-Acetate). Commonly, the reaction is demonstrated utilizing the enhancer...article 2011
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Volkov, V.V. (author), Lebedeva, V.I. (author), Petrova, I.V. (author), Bobyl, A.V. (author), Konnikov, S.G. (author), Roldughin, V.I. (author), van Erkel, J. (author), Tereshchenko, G.F. (author)Principal approaches for the preparation of catalytic membrane reactors based on polymer membranes containing palladium nanoparticles and for the description of their characteristics are presented. The method for the development of adlayers composed of palladium nanoparticles and their aggregates on the surface of hydrophobic polypropylene...article 2011
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Maddalena, F. (author), Meijer, E.J. (author), Asadi, K. (author), de Leeuw, D.M. (author), Blom, P.W.M. (author), TNO Industrie en Techniek (author)The kinetics of acid doping of the semiconductor regioregular poly-3-hexylthiophene with vaporized chlorosilane have been investigated using field-effect transistors. The dopant density has been derived as a function of temperature and exposure time from the shift in the pinch-off voltage, being the gate bias where current starts to flow. The...article 2010
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Polder, R.B. (author), Peelen, W.H.A. (author), Neeft, E.A.C. (author), Stoop, B.T.J. (author), TNO Bouw en Ondergrond (author)Over the last 25 years, cathodic protection (CP) of reinforced concrete structures suffering from chloride induced reinforcement corrosion has shown to be successful and durable. CP current causes steel polarisation, electrochemical reactions and ion transport in the concrete. CP systems are designed based on experience, which results in...article 2010
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van Wijk, R. (author), van der Greef, J. (author), van Wijk, E. (author), TNO Kwaliteit van Leven (author)The relationship between connective tissue and meridian function is discussed in terms of energy transmission. The network of hydrogen-bonded water molecules interspersed within the collagen fibrillar matrix is especially significant for both the sensitivity of connective tissue to weak signals of mechanical pressure, heat, or electricity and...article 2010
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Fischer, H.R. (author), Tempelaars, K. (author), Kerpershoek, A.M. (author), Dingemans, T. (author), Iqbal, M. (author), Lonkhuyzen, H. (author), Iwanowsky, B. (author), Semprimoschnig, C. (author), TNO Industrie en Techniek (author)Polimide-block-polydimethylsiloxane (PI-b-PDMS) block copolymers have been synthesized from commercially available amino-terminated polysiloxanes with different molecular weights, for use as polymeric materials resistant to the low earth orbit (LEO) space environment. A structural optimization with respect to maximum environmental protection has...article 2010
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TNO Bouw en Ondergrond (author), Hultin, K.A.H. (author), Nilsson, E.D. (author), Krejci, R. (author), Mrtensson, E.M. (author), Ehn, M. (author), Hagström, Å. (author), de Leeuw, G. (author)Bubbles bursting from whitecaps are considered to be the most effective mechanism for particulate matter to be ejected into the atmosphere from the Earth's oceans. To realistically predict the climate effect of marine aerosols, global climate models require process-based understanding of particle formation from bubble bursting. During a cruise...article 2010