Molecular modeling of Mannich phenols as reactivators of human acetylcholinesterase inhibited by A-series nerve agents

Pharmacokinetics of three oximes in a guinea pig model and efficacy of combined oxime therapy

Synthesis and in vitro evaluation of novel non-oximes for the reactivation of nerve agent inhibited human acetylcholinesterase

Theoretical NMR and conformational analysis of solvated oximes for organophosphates-inhibited acetylcholinesterase reactivation

Interactions between acetylcholinesterase, toxic organophosphorus compounds and a short series of structurally related non-oxime reactivators: Analysis of reactivation and inhibition kinetics in vitro

Theoretical NMR and conformational analysis of solvated oximes for organophosphates-inhibited acetylcholinesterase reactivation

Discovery of a potent non-oxime reactivator of nerve agent inhibited human acetylcholinesterase

Application of the Ugi Multicomponent Reaction in the Synthesis of Reactivators of Nerve Agent Inhibited Acetylcholinesterase

Docking and molecular dynamics studies of peripheral site ligand–oximes as reactivators of sarin-inhibited human acetylcholinesterase

Increasing nerve agent treatment efficacy by P-glycoprotein inhibition

Peripheral site ligand-oxime conjugates: A novel concept towards reactivation of nerve agent-inhibited human acetylcholinesterase

Peripheral site ligand conjugation to a non-quaternary oxime enhances reactivation of nerve agent-inhibited human acetylcholinesterase

Microbial metabolomics with gas chromatography/mass spectrometry

Toxicokinetics of the nerve agent (±)-VX in anesthetized and atropinized hairless guinea pigs and marmosets after intravenous and percutaneous administration

Efficacy of HI-6 and HLÖ-7 in preventing incapacitation following nerve agent poisoning

Comparison of the therapeutic effects and pharmacokinetics of HI-6, HLo-7, HGG-12, HGG-42 and obidoxime following non-reactivatable acetylcholinesterase inhibition in rats

Therapy of organophosphate poisoning in the rat by direct effects of oximes unrelated to ChE reactivation

The bispyridinium-dioxime HLö-7. A potent reactivator for acetylcholinesterase inhibited by the stereoisomers of tabun and soman

High doses of soman protect against organophosphorus-induced delayed polyneuropathy but tabun does not

Isolation, anticholinesterase properties, and acute toxicity in mice of the four stereoisomers of the nerve agent soman