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van Wendel de Joode, B. (author), van Hemmen, J.J. (author), Meijster, T. (author), Major, V. (author), London, L. (author), Kromhout, H. (author), TNO Kwaliteit van Leven (author)Valid and reliable semi-quantitative dermal exposure assessment methods for epidemiological research and for occupational hygiene practice, applicable for different chemical agents, are practically nonexistent. The aim of this study was to assess the reliability of a recently developed semi-quantitative dermal exposure assessment method (DREAM)...article 2005
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van Wendel de Joode, B. (author), Tielemans, E. (author), Vermeulen, R. (author), Wegh, H. (author), Kromhout, H. (author), TNO Kwaliteit van Leven (author)Charcoal cloth pads have been used to assess volatile chemicals on the skin in a laboratory setting; however, they have not yet been applied to measure dermal exposure in occupational settings. This study aimed at evaluating whether charcoal pads can be used to assess dermal exposure to benzene and toluene in workers of a petrochemical plant....article 2005
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Weevers, H.J.A. (author), van der Beek, A.J. (author), Anema, J.R. (author), van der Wal, G. (author), van Mechelen, W. (author), TNO Kwaliteit van Leven (author)Objectives. The objective was to answer the following questions: What is the prevalence of potentially work-related diseases in the general practice population? What is the incidence of consulting a GP for a potentially work-related disease? What is the relationship between diseases seen in general practice and work ability? Methods. Cochrane...article 2005
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Gijsbers, J.H.J. (author), Tielemans, E. (author), Brouwer, D.H. (author), van Hemmen, J.J. (author), TNO Voeding (author)Introduction: Limited quantitative information is available on dermal exposure to chemicals during various industrial activities. Therefore, within the scope of the EU-funded RISKOFDERM project, potential dermal exposure was measured during three different tasks: filling, loading and brushing. DEGBE (2-(2-butoxyethoxy)ethanol) was used as a ...article 2004
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Kromhout, H. (author), Fransman, W. (author), Vermeulen, R. (author), Roff, M. (author), van Hemmen, J.J. (author), TNO Voeding (author)Introduction: The RISKOFDERM project collected task-based estimates of potential dermal exposure from a wide range of industries and services from around Europe. A formal statistical analysis was carried out to explore the main components of variability in dermal exposure levels. The central research question was to what extent dermal exposure...article 2004
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Oral-to-inhalation route extrapolation in occupational health risk assessment: A critical assessmentRennen, M.A.J. (author), Bouwman, T. (author), Wilschut, A. (author), Bessems, J.G.M. (author), de Heer, C. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)Due to a lack of route-specific toxicity data, the health risks resulting from occupational exposure are frequently assessed by route-to-route (RtR) extrapolation based on oral toxicity data. Insight into the conditions for and the uncertainties connected with the application of RtR extrapolation has not been clearly described in a systematic...article 2004
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TNO Preventie en Gezondheid (author), Riese, H. (author), van Doornen, L.J.P. (author), Houtman, I.L.D. (author), de Geus, E.J.C. (author)Objective. This study examined the effects of exposure to job strain on independent predictors of cardiovascular disease (ambulatory blood pressure, heart rate, and heart rate variability). Methods. The participants comprised a homogeneous group of 159 healthy female nurses [mean age 35.9 (SD 8.5) years]. The choice of this population minimized...article 2004
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TNO Preventie en Gezondheid (author), van den Heuvel, S.G. (author), Ariëns, G.A.M. (author), Boshuizen, H.C. (author), Hoogendoorn, W.E. (author), Bongers, P.M. (author)This study aimed at determining the prognostic factors related to the recurrence of low-back pain and future sickness absence due to low-back pain. Data were used from a prospective cohort study in a working population with a three year follow-up period. They were collected with annual questionnaires. A generalised estimating equation model was...article 2004
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TNO Preventie en Gezondheid (author), Elders, L.A.M. (author), Burdorf, A. (author), Öry, F.G. (author)The number of native Dutch and Turkish workers receiving a permanent disability pension in the Netherlands is still rising. To assess ethnic differences in disability risk between Dutch and Turkish scaffolders, a retrospective study was conducted within a large scaffolding company. Medical files for the period 1981-2000 were used to gather...article 2004
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Hildebrandt, V.H. (author), Bongers, P.M. (author), van Dijk, F.J.H. (author), Kemper, H.C.G. (author), Dul, J. (author), TNO Preventie en Gezondheid (author)An epidemiological study was carried out to explore the relationship between climatic factors and non-specific low-back and neck-shoulder symptoms in working populations. In a review of published literature, 27 studies were found which related climatic factors to musculoskeletal symptoms, but none of these studies specifically addressed the...article 2002
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Willems, J.H.B.M. (author)The Health Council of the Netherlands has published its advisory report on Repetitive Strain Injury (RSI). The report provides clear information on the state of this syndrome, including the definition of the problem, the epidemiology, various hypothetical pathophysiological mechanisms, occupational and personal risk factors, and possible methods...article 2002
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Hoogendoorn, W.E. (author), Bongers, P.M. (author), de Vet, H.C.W. (author), Ariëns, G.A.M. (author), van Mechelen, W. (author), Bouter, L.M. (author)Objective: To determine whether physical and psychosocial load at work influence sickness absence due to low back pain. Methods: The research was a part of the study on musculoskeletal disorders, absenteeism, stress, and health (SMASH), a 3 year prospective cohort study on risk factors for musculoskeletal disorders. Workers from 21 companies...article 2002
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Ariëns, G.A.M. (author), Bongers, P.M. (author), Douwes, M. (author), Miedema, M.C. (author), Hoogendoorn, W.E. (author), van der Wal, G. (author), Bouter, L.M. (author), van Mechelen, W. (author)Objective: To study the relation between neck pain and work related neck flexion, neck rotation, and sitting. Methods: A prospective cohort study was performed with a follow up of 3 years among 1334 workers from 34 companies. Work related physical load was assessed by analysing objectively measured exposure data (video recordings) of neck...article 2001
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Hildebrandt, V.H. (author), Bongers, P.M. (author), van Dijk, F.J. (author), Kempers, H.C.G. (author), Dul, J. (author)The article describes the Dutch Musculoskeletal Questionnaire (DMQ) for the analysis of musculoskeletal workload and associated potential hazardous working conditions as well as musculoskeletal symptoms in worker populations. Its qualities are explored using a database of 1,575 workers in various occupations who completed the questionnaire. The...article 2001
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Cherrie, J.W. (author), Brouwer, D.H. (author), Roff, M. (author), Vermeulen, R. (author), Kromhout, H. (author)Fluorescent tracers provide a way of simultaneously assessing the mass of a contaminant hazardous substance on the surface of the skin of a worker and the area of skin exposed. These parameters, along with the duration of exposure and the estimated contaminant concentration in the skin contamination layer, can be used to calculate the likely...article 2000
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Brouwer, D.H. (author), Boeniger, M.F. (author), van Hemmen, J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Hand wash and skin wipes are major techniques that have been used for dermal exposure sampling. Both techniques remove chemicals either deposited on or transferred to the skin contaminant layer by a combination of chemical and mechanical actions. The paper overviews identified methods and techniques, with emphasis on sampling parameters and...article 2000
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Brouwer, D.H. (author), Lansink, C.M. (author), Cherrie, J.W. (author), van Hemmen, J.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)The range of dermal exposure to non-volatile compounds during spray painting was studied in a semi-experimental study involving three enterprises and 12 painters. A fluorescent tracer was added to the paint and deposition of the tracer on clothing and uncovered parts of the skin was assessed using video imaging and processing techniques. A...article 2000
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Ariëns, G.A.M. (author), van Mechelen, W. (author), Bongers, P.M. (author), van der Wal, G. (author), Bouter, L.M. (author)To identify physical risk factors for neck pain, a systematic review of the literature was carried out. Based on methodological quality and study design, 4 levels of evidence were defined to establish the strength of evidence for the relationship between risk factors and neck pain. Altogether, 22 cross-sectional studies, 2 prospective cohort...article 2000
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Bierman, E.P.B. (author), Brouwer, D.H. (author), van Hemmen, J.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Knowledge of the level of exposure is important for health risk estimation and risk management. Recently, the occurrence of dermal exposure in many situations has been recognized and estimated to be relevant for worker health. Dermal exposure measurement techniques are therefore needed and several approaches have been taken to assess this type...article 1998
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Houtman, I.L.D. (author), Goudswaard, A. (author), Dhondt, S. (author), van der Grinten, M.P. (author), Hildebrandt, V.H. (author), van der Poel, E.G.T. (author)Objectives - Due to recent changes in legislation on occupational health and safety, a national monitor on stress and physical load was developed in The Netherlands to monitor (a) risks and consequences of stress and physical load at work, (b) preventive actions in companies to reduce these risks, and (c) organisational and environmental...article 1998