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Fransman, W. (author), Schinkel, J. (author), Meijster, T. (author), van Hemmen, J. (author), Tielemans, E. (author), Goede, H. (author), TNO Kwaliteit van Leven (author)Objectives: This paper describes the development and evaluation of an evidence database on the effectiveness of risk management measures (RMMs) to control inhalation exposure. This database is referred to as Exposure Control Efficacy Library (ECEL). Methods: A comprehensive review of scientific journals in the occupational hygiene field was...article 2008
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Meijster, T. (author), Tielemans, E. (author), Schinkel, J. (author), Heederik, D. (author), TNO Kwaliteit van Leven (author)Objectives: To effectively decrease occupational exposure to flour dust and related allergens, detailed information on exposure determinants and effectiveness of control measures is essential. In this paper, we use personal real-time exposure measurements to get more insight into the relationship between specific work characteristics, including...article 2008
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Spaan, S. (author), Schinkel, J. (author), Wouters, I.M. (author), Preller, L. (author), Tielemans, E. (author), Nij, E.T. (author), Heederik, D. (author), TNO Kwaliteit van Leven (author)Objectives: Workers in many industries are exposed to endotoxins, which may cause adverse health effects. In exposure assessment, information about exposure variability is essential. However, variability in exposure has rarely been investigated for biological agents and more specifically for endotoxin. Therefore, variance components and...article 2008
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Tielemans, E. (author), Schneider, T. (author), Goede, H. (author), Tischer, M. (author), Warren, N. (author), Kromhout, H. (author), van Tongeren, M. (author), van Hemmen, J. (author), Cherrie, J.W. (author), TNO Kwaliteit van Leven (author)The present paper proposes a source-receptor model to schematically describe inhalation exposure to help understand the complex processes leading to inhalation of hazardous substances. The model considers a stepwise transfer of a contaminant from the source to the receptor. The conceptual model is constructed using three components, i.e. (i) the...article 2008
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van Hamberg - Reenen, H.H. (author), van der Beek, A.J. (author), Blatter, B. (author), van der Grinten, M.P. (author), van Mechelen, W. (author), Bongers, P.M. (author), TNO Kwaliteit van Leven (author)The objective of this prospective cohort study was to evaluate if peak or cumulative musculoskeletal discomfort may predict future low-back, neck or shoulder pain among symptom-free workers. At baseline, discomfort per body region was rated on a 10-point scale six times during a working day. Questionnaires on pain were sent out three times...article 2008
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Tielemans, E. (author), Bretveld, R. (author), Schinkel, J. (author), de Wendel van - Joode, B. (author), Kromhout, H. (author), Gerritsen-Ebben, R. (author), Roeleveld, N. (author), Preller, L. (author), TNO Kwaliteit van Leven (author)The aim of this study was to assess exposure to pesticides for a longitudinal epidemiological study on adverse reproduction effects among greenhouse workers. Detailed information on pesticide use among greenhouse workers was obtained on a monthly basis through self-administered questionnaires and subsequent workplace surveys. Questionnaires were...article 2007
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Bongers, P.M. (author), TNO Arbeid (author)High quality studies that evaluate cost‐effective interventions in neck and upper extremity musculoskeletal conditions are needed.article 2007
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Douwes, M. (author), de Kraker, H. (author), Blatter, B.M. (author), TNO Kwaliteit van Leven (author)A long duration of computer use is known to be positively associated with Work Related Upper Extremity Disorders (WRUED). Self-report by questionnaire is commonly used to assess a worker's duration of computer use. The aim of the present study was to assess the validity of self-report and computer use software (WorkPace®) to assess the duration...article 2007
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IJmker, S. (author), Huysmans, M.A. (author), Blatter, B.M. (author), van der Beek, A.J. (author), van Mechelen, W. (author), Bongers, P.M. (author), TNO Kwaliteit van Leven (author)Worldwide, millions of office workers use a computer. Reports of adverse health effects due to computer use have received considerable media attention. This systematic review summarises the evidence for a relationship between the duration of work time spent using the computer and the incidence of hand-arm and neck-shoulder symptoms and disorders...article 2007
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Links, I. (author), Jagt, K.E.V.D. (author), Christopher, Y. (author), Lurvink, M. (author), Schinkel, J. (author), Tielemans, E. (author), Hemmen, J.J.V. (author), TNO Kwaliteit van Leven (author)Exposure data on biocides are relatively rare in published literature, especially for secondary exposure. This is also the case for antifouling exposure. Therefore, a field study was carried out measuring exposure to antifouling paints. Both primary exposure (rolling and spraying) and secondary exposure (during sand blasting) were studied....article 2007
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Pronk, A. (author), Preller, L. (author), Raulf-Heimsoth, M. (author), Jonkers, I.C.L. (author), Lammers, J.-W. (author), Wouters, I.M. (author), Doekes, G. (author), Wisnewski, A.V. (author), Heederik, D. (author), TNO Kwaliteit van Leven (author)Rationale: Associations between oligomeric isocyanate exposure, sensitization, and respiratory disease have received little attention, despite the extensive use of isocyanate oligomers. Objectives: To investigate exposure-response relationships of respiratory symptoms and sensitization in a large population occupationally exposed to isocyanate...article 2007
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Can sickness absence be reduced by stress reduction programs: On the effectiveness of two approachesvan Rhenen, W. (author), Blonk, R.W.B. (author), Schaufeli, W.B. (author), van Dijk, F.J.H. (author), TNO Kwaliteit van Leven (author)Objectives: The aim of the study was to evaluate the effectiveness of two brief preventive stress reduction programs - a cognitive focused program and a combined intervention of physical exercise and relaxation - on sickness absence in stressed and non-stressed employees working in various jobs in a telecom company. Methods: The study was...article 2007
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Geng, Q. (author), Holme, I. (author), den Hartog, E.A. (author), Havenith, G. (author), Jay, O. (author), Malchaires, J. (author), Piette, A. (author), Rintama, H. (author), Rissanen, S. (author), TNO Defensie en Veiligheid (author)Objectives: At the request of the European Commission and in the framework of the European Machinery Directive, research was performed in five different laboratories to develop specifications for surface temperature limit values for the short-term accidental touching of the fingertip with cold surfaces. Methods: Data were collected in four...article 2006
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Meijster, T. (author), Tielemans, E. (author), de Pater, N. (author), Heederik, D. (author), TNO Kwaliteit van Leven (author)Introduction: Recent studies have shown that even low exposure levels to flour dust and related allergens can cause severe respiratory symptoms. In The Netherlands the Dutch government and responsible branch organizations [from bakeries (traditional & industrial), flour mills and bakery ingredient producers] signed a covenant to reduce exposure...article 2006
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Bogdanovic, J. (author), Koets, M. (author), Sander, I. (author), Wouters, I. (author), Meijster, T. (author), Heederik, D. (author), van Amerongen, A. (author), Doekes, G. (author), TNO Kwaliteit van Leven (author)Background: Occupational allergen exposure assessment usually requires airborne dust sampling at the worksite followed by dust extraction and enzyme immunoassay (EIA) analysis at the laboratory. Use of semiquantitative lateral flow immunoassays (LFIAs) may allow a more rapid detection procedure with direct on-site demonstration of a bioallergen...article 2006
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Arts, J.H.E. (author), Mommers, C. (author), de Heer, C. (author), TNO Kwaliteit van Leven (author)A literature study was performed to evaluate dose-response relationships and no-effect levels for sensitization and elicitation in skin- and respiratory allergy. With respect to the skin, dose-response relationships and no-effect levels were found for both intradermal and topical induction, as well as for intradermal and topical elicitation of...article 2006
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Pronk, A. (author), Yu, F. (author), Vlaanderen, J. (author), Tielemans, E. (author), Preller, L. (author), Bobeldijk, I. (author), Deddens, J.A. (author), Latza, U. (author), Baur, X. (author), Heederik, D. (author), TNO Kwaliteit van Leven (author)Objectives: To study inhalation and dermal exposure to hexamethylene diisocyanate (HDI) and its oligomers as well as personal protection equipment (PPE) use during task performance in conjunction with urinary hexamethylene diamine (HDA) in car body repair shop workers and industrial spray painters. Methods: Personal task based inhalation samples...article 2006
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TNO Kwaliteit van Leven (author), IJmker, S. (author), Blatter, B.M. (author), van der Beek, A.J. (author), van Mechelen, W. (author), Bongers, P.M. (author)Background: This article describes the background and study design of the PROMO study (Prospective Research on Musculoskeletal disorders in Office workers). Few longitudinal studies have been performed to investigate the risk factors responsible for the incidence of hand, arm, shoulder and neck symptoms among office workers, given the...article 2006
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van den Heuvel, S.G. (author), van der Beek, A.J. (author), Blatter, B.M. (author), Hoogendoorn, W.E. (author), Bongers, P.M. (author), TNO Kwaliteit van Leven (author)The aim of this study was to investigate the relationship between psychosocial work characteristics and neck and upper limb symptoms and to examine to what extent this relationship could be explained by other risk factors. Data were used from a prospective cohort study in a working population, with a follow-up period of 3 years. The 3-year...article 2005
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- van der Molen, H. (author), Koningsveld, E. (author), Haslam, R. (author), Gibb, A. (author), TNO Kwaliteit van Leven (author) article 2005