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Fiamoncini, J. (author), Donado-Pestana, C.M. (author), Duarte, G.B.S. (author), Rundle, M. (author), Thomas, E.L. (author), Kiselova-Kaneva, Y. (author), Gundersen, T.E. (author), Bunzel, D. (author), Trezzi, J.P. (author), Kulling, S.E. (author), Hiller, K. (author), Sonntag, D. (author), Ivanova, D. (author), Brennan, L. (author), Wopereis, S. (author), van Ommen, B. (author), Frost, G. (author), Bell, J. (author), Drevon, C.A. (author), Daniel, H. (author)Insulin secretion following ingestion of a carbohydrate load affects a multitude of metabolic pathways that simultaneously change direction and quantity of interorgan fluxes of sugars, lipids and amino acids. In the present study, we aimed at identifying markers associated with differential responses to an OGTT a population of healthy adults. By...article 2022
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Pasman, W.J. (author), Memelink, R.G. (author), den Bosch, J.V.V. (author), Begieneman, M.P.V. (author), van den Brink, W.J. (author), Weijs, P.J.M. (author), Wopereis, S. (author)Background: Recent research showed that subtypes of patients with type 2 diabetes may differ in response to lifestyle interventions based on their organ-specific insulin resistance (IR). (2) Methods: 123 Subjects with type 2 diabetes were randomized into 13-week lifestyle intervention, receiving either an enriched protein drink (protein+) or an...article 2020
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TNO Kwaliteit van Leven (author), Stroeve, J.H.M. (author), van Wietmarschen, H. (author), Kremer, B.H.A. (author), van Ommen, B. (author), Wopereis, S. (author)Nutrition research is struggling to demonstrate beneficial health effects, since nutritional effects are often subtle and long term. Health has been redefined as the ability of our body to cope with daily-life challenges. Physiology acts as a well-orchestrated machinery to adapt to the continuously changing environment. We term this adaptive...article 2015
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Assessment of inflammatory resilience in healthy subjects using dietary lipid and glucose challengesWopereis, S. (author), Wolvers, D. (author), van Erk, M.J. (author), Gribnau, M. (author), Kremer, S.H.A. (author), van Dorsten, F.A. (author), Boelsma, E. (author), Garczarek, U. (author), Cnubben, N. (author), Frenken, L. (author), der Logt P, van (author), Hendriks, H.F. (author), Albers, R. (author), van Duynhoven, J. (author), van Ommen, B. (author), Jacobs, D.M. (author)Background: Resilience or the ability of our body to cope with daily-life challenges has been proposed as a new definition of health, with restoration of homeostasis as target resultant of various physiological stress responses. Challenge models may thus be a sensitive measure to study the body’s health. The objective of this study was to select...article 2013