Selective lesions by manganese and extensive damage by iron after local injection into rat striatum or hippocampus

Regional 45Ca2+ accumulation and analysis of monoamines and metabolites in dissected tissues were used to localize, quantify, and characterize brain damage after intracerebral injections of Mn2+ into striatum and hippocampus. The specificity of Mn2+-induced lesions is described in relation to brain damage produced by local Fe2+ or 6-...

Pressure-diameter relationships of segments of human finger arteries

Pressure-diameter relationships of segments of human finger arteries, aged 57-85 years, were measured in vitro. The arteries, obtained at autopsy within 48 h after death, were stored in glucose-free Tyrode at 4 degrees C. Experiments began within 40 h after autopsy. The diameter responses to various transmural pressure changes, with and without...

Effect of work load on free and sulfate-conjugated plasma catecholamines, prolactin, and cortisol

The effects of maximal performance capacity and different work load intensities on the response of free and sulfate-conjugated plasma catecholamines, prolactin (PRL), and cortisol were studied in six healthy male volunteers. In a first experiment, the volunteers had to perform a step-wise incremental bicycle ergometer test to determine the onset...

Catecholamine excretion, conscience function and aggressive behaviour

This report deals with a study carried out among 46 12-17 year old boys, of the relationship between: (1) the excretion of waste products of catecholamines (methyladrenaline and methylnoradrenaline) and creatinine, (2) aggressive behaviour in a laboratory setting, and (3) data obtained via a conscience function questionnaire. The hypothesis that...