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Bressot, C. (author), Shandilya, N. (author), Jayabalan, T. (author), Fayet, G. (author), Voetz, M. (author), Meunier, L. (author), Le Bihan, O. (author), Aguerre-Chariol, O. (author), Morgeneyer, M. (author)Characterization of the exposition to nanoparticles and nano-objects at workplaces is a huge technical challenge. Workplace exposure during short durations is particularly difficult to detect due to the low performances of the samplers. This article proposes a solution allowing for characterizing emissions at workplaces and presents the results...article 2018
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van Groenestijn, G.J.A. (author), Meulendiiks, N.M.M. (author), Volker, A.W.F. (author), van Neer, P.L.M.J. (author), Buskens, P.J.P. (author)Nanoparticles are applied in an increasing number of products (e.g. medicine, food and cosmetics). There is a need to real-time monitor the growth of nanoparticles during production inside the chemical reactor. However, standard particle sizing methods such as dynamic light scattering (DLS) and transmission electron microscopy (TEM) cannot do...conference paper 2018
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Koivisto, A.J. (author), Kling, K.I. (author), Fonseca, A.S. (author), Brostrøm Bluhme, A. (author), Moreman, M. (author), Yu, M. (author), Costa, A.L. (author), Giovanni, B. (author), Ortelli, S. (author), Fransman, W. (author), Vogel, U. (author), Jensen, K.A. (author)Nanoscale TiO2 (nTiO2) is manufactured in high volumes and is of potential concern in occupational health. Here, we measured workers exposure levels while ceramic honeycombs were dip coated with liquid photoactive nanoparticle suspension and dried with an air blade. The measured nTiO2 concentration levels were used to assess process specific...article 2018
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Fonseca, A.S. (author), Kuijpers, E. (author), Kling, K.I. (author), Levin, M. (author), Koivisto, A.J. (author), Nielsen, S.H. (author), Fransman, W. (author), Fedutik, Y. (author), Jensen, K.A. (author), Koponen, I.K. (author)Fume hoods are one of the most common types of equipment applied to reduce the potential of particle exposure in laboratory environments. A number of previous studies have shown particle release during work with nanomaterials under fume hoods. Here, we assessed laboratory workers’ inhalation exposure during synthesis and handling of CuO, TiO2...article 2018
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Meulendijks, N. (author), van Ee, R. (author), Stevens, R. (author), Mourad, M. (author), Verheijen, M. (author), Kambly, N. (author), Armenta, R. (author), Buskens, P. (author)To tailor the properties of nanoparticles and nanocomposites, precise control over particle size is of vital importance. Real-time monitoring of particle size during bottom-up synthesis in liquids would allow a detailed study of particle nucleation and growth, which provides valuable insights in the mechanism of formation of the nanoparticles....article 2018
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Heringa, M.B. (author), Peters, R.J.B. (author), Bleys, R.L.A.W. (author), van der Lee, M.K. (author), Tromp, P.C. (author), van Kesteren, P.C.E. (author), van Eijkeren, J.C.H. (author), Undas, A.K. (author), Oomen, A.G. (author), Bouwmeester, H. (author)Background: Titanium dioxide (TiO2) is produced at high volumes and applied in many consumer and food products. Recent toxicokinetic modelling indicated the potential of TiO2 to accumulate in human liver and spleen upon daily oral exposure, which is not routinely investigated in chronic animal studies. A health risk from nanosized TiO2 particle...article 2018
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Markus, A.A. (author), Krystek, P. (author), Tromp, P.C. (author), Parsons, J.R. (author), Roex, E.W.M. (author), de Voogt, P. (author), Laane, R.W.P.M. (author)We investigated the occurrence of metal-based nanoparticles in a natural system, the river Dommel in the Netherlands. The river itself is well-studied as far as hydrology and water quality is concerned, easily accessible and contains one major wastewater treatment plant discharging onto this river. We sampled water from various locations along...article 2018
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van Wezel, A.P. (author), van Lente, H. (author), van de Sandt, J.J.M. (author), Bouwmeester, H. (author), Vandeberg, R.L.J. (author), Sips, A.J.A.M. (author)Governments invest in “key enabling technologies,” such as nanotechnology, to solve societal challenges and boost the economy. At the same time, governmental agencies demand risk reduction to prohibit any often unknown adverse effects, and industrial parties demand smart approaches to reduce uncertainties. Responsible research and innovation ...article 2018
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Vilela, S.M.F. (author), Salcedo-Abraira, P. (author), Colinet, I. (author), Salles, F. (author), de Koning, M.C. (author), Joosen, M.J.A. (author), Serre, C. (author), Horcajada, P. (author)The three-dimensional (3D) microporous titanium aminoterephthalate MIL-125-NH_2 (MIL: Material of Institut Lavoisier) was successfully isolated as monodispersed nanoparticles, which are compatible with intravenous administration, by using a simple, safe and low-cost synthetic approach (100 °C/32 h under atmospheric pressure) so that for the...article 2017
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Gallocchio, F. (author), Biancotto, G. (author), Cibin, V. (author), Losasso, C. (author), Belluco, S. (author), Peters, R. (author), van Bemmel, G. (author), Cascio, C. (author), Weigel, S. (author), Tromp, P. (author), Gobbo, F. (author), Catania, S. (author), Ricci, A. (author)Silver nanoparticles (AgNPs) are of interest due to their antimicrobial activity and are seen as potential candidates to replace antibiotics in animal husbandry. A few studies have focused on this new application, but they lack any considerations about residual accumulation of AgNPs in edible animal tissues and animal products. In this research,...article 2017
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Matsuhisa, N. (author), Inoue, D. (author), Zalar, P. (author), Jin, H. (author), Matsuba, Y. (author), Itoh, A. (author), Yokota, T. (author), Hashizume, D. (author), Someya, T. (author)Printable elastic conductors promise large-area stretchable sensor/actuator networks for healthcare, wearables and robotics. Elastomers with metal nanoparticles are one of the best approaches to achieve high performance, but large-area utilization is limited by difficulties in their processability. Here we report a printable elastic conductor...article 2017
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Teunissen, J.P. (author), Abbel, R. (author), Hendriks, R. (author), Groen, P. (author)The necessary metal-based inks typically consist of silver nanoparticles dispersed in a liquid carrier medium. In order to keep the ink stable and printable, the agglomeration and sedimentation of these functional components need to be prevented as long as they are not printed onto a substrate. This is typically done by the addition of organic ...bookPart 2017
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Kooter, I.M. (author), Grollers-Mulderij, M. (author), Duistermaat, E. (author), Kuper, C.F. (author)Mucilair 3D bronchial airway models, cultured at an air-liquid interface, were exposed to aerosols of copper oxide (CuO) nanoparticles in Vitrocell air exposure modules. Four cell donors, four exposure modules and four exposure concentrations were varied within four different exposure sessions using a statistical experimental design called a...article 2017
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Bussink, P.G.W. (author), Volatier, J.B. (author), van der Walle, P. (author), Fritz, E.C. (author), van der Donck, J.C.J. (author)The Rapid Nano is a particle inspection system developed by TNO for the qualification of EUV reticle handling equipment. The detection principle of this system is dark-field microscopy. The performance of the system has been improved via model-based design. Through our model of the scattering process we identified two key components to improving...conference paper 2016
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Koek, W.D. (author), van Zwet, E.J. (author), Sadeghian Marnani, H. (author)Traditionally, (dark field) imaging based, particle detection systems rely on identifying a particle based on its irradiance. It can be shown that for a very smooth wafer with 0.1 nm surface roughness (rms) this approach results in a particle detection limit larger than 20 nm. By carefully studying the physical mechanism behind this practical...conference paper 2016
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Brouwer, D. (author), Boessen, R. (author), van Duuren-Stuurman, B. (author), Bard, D. (author), Moehlmann, C. (author), Bekker, C. (author), Fransman, W. (author), Entink, R.K. (author)Tiered or stepwise approaches to assess occupational exposure to nano-objects, and their agglomerates and aggregates have been proposed, which require decision rules (DRs) to move to a next tier, or terminate the assessment. In a desk study the performance of a number of DRs based on the evaluation of results from direct reading instruments was...article 2016
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Kooter, I.M. (author), Grollers-Mulderij, M. (author), Steenhof, M. (author), Duistermaat, E. (author), van Acker, F.A.A. (author), Staal, Y.C.M. (author), Tromp, P.C. (author), Schoen, E.D. (author), Kuiper, C.F. (author), van Someren, E.P. (author)There is a need for representative in vitro models to assess the effects of airborne particles on lung health. The ob-jective of this study was to assess the cellular effects of cerium oxide (Ce02) particles exposed via an air—liquid interface in three relevant cell models in parallel. BEAS-2B, A549, and MucilAirTM cells were exposed for 1 hour...article 2016
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Flegler, A. (author), Schneider, M. (author), Prieschl, J. (author), Stevens, R. (author), Vinnay, T. (author), Mandel, K. (author)Here, we report a continuous flow synthesis of nano LDH, comprising a continuous precipitation process using static mixers and followed by an immediate cleaning process via a semi-continuous centrifuge to obtain the final product in one-go. Via this synthesis setup, it is possible to independently vary the concentrations of the reactants during...article 2016
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Polino, G. (author), Abbel, R. (author), Shanmugam, S. (author), Bex, G.J.P. (author), Hendriks, R. (author), Brunetti, F. (author), Di Carlo, A. (author), Andriessen, R. (author), Galagan, Y. (author)A set of three commercial copper nanoparticle based inkjet inks has been benchmarked with respect to their potential to form conducting printed structures for future applications in organic electronic devices. Significant differences were observed in terms of jetting properties, spreading behaviour and line formation on a number of relevant...article 2016
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Brouwer, D.H. (author), Spaan, S. (author), Roff, M. (author), Sleeuwenhoek, A. (author), Tuinman, I. (author), Goede, H. (author), van Duuren-Stuurman, B. (author), Filon, F.L. (author), Bello, D. (author), Cherrie, J.W. (author)Over the past decade, the primary focus of nanotoxicology and nanoenvironmental health and safety efforts has been largely on inhalation exposure to engineered nanomaterials, at the production stage, and much less on considering risks along the life cycle of nano-enabled products. Dermal exposure to nanomaterials and its health impact has been...article 2016