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Tabasi, A. (author), Kingma, I. (author), de Looze, M.P. (author), van Dijk, W. (author), Koopman, A.S. (author), van Dieën, J.H. (author)Back support exoskeletons are designed to prevent work-related low-back pain by reducing mechanical loading. For actuated exoskeletons, support based on moments actively produced by the trunk muscles appears a viable approach. The moment can be estimated by a biomechanical model. However, one of the main challenges here is the feasibility of...article 2020
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Koopman, A.S. (author), Naf, M. (author), Baltrusch, S.J. (author), Kingma, I. (author), Rodriguez-Guerrero, C. (author), Babic, J. (author), de Looze, M.P. (author), van Dieën, J.H. (author)The number one cause of disability in the world is low-back pain, with mechanical loading as one of the major risk factors. To reduce mechanical loading, exoskeletons have been introduced in the workplace. Substantial reductions in back muscle activity were found when using the exoskeleton during static bending and manual materials handling....article 2020
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Hiemstra-van Mastrigt, S. (author), Kamp, I. (author), van Veen, S.A.T. (author), Vink, P. (author), Bosch, T. (author)New technologies have led to an increasingly sedentary lifestyle. Sedentary behaviour is characterised by physical inactivity and is associated with several health risks. This excessive sitting does not only take place in the office or at home, but also during daily commute. Therefore, BMW AG developed an active seating system for the back seat...article 2015
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Ellegast, R.P. (author), Kraft, K. (author), Groenesteijn, L. (author), Krause, F. (author), Berger, H. (author), Vink, P. (author)Prolonged and static sitting postures provoke physical inactivity at VDU workplaces and are therefore discussed as risk factors for the musculoskeletal system. Manufacturers have designed specific dynamic office chairs featuring structural elements which promote dynamic sitting and therefore physical activity. The aim of the present study was to...article 2012
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Bosch, T. (author), de Looze, M.P. (author), Kingma, I. (author), Visser, B. (author), van Dieën, J.H. (author), TNO Kwaliteit van Leven (author)The purpose of this study was to determine whether objective electromyographical manifestations of muscle fatigue develop in the upper trapezius muscle in two assembly tasks involving contractions of different low-intensity levels (8% and 12% MVC) and whether these indications of fatigue are homogeneously distributed across different muscle...article 2009
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van Dartel, D.A.M. (author), Pennings, J.L.A. (author), Hendriksen, P.J.M. (author), van Schooten, F.J. (author), Piersma, A.H. (author), TNO Kwaliteit van Leven (author)The Embryonic Stem cell Test (EST) is an in vitro alternative test designed for the prediction of embryotoxicity. The endpoint of the test is the interference with mesoderm-derived cardiac muscle differentiation observed under the microscope as beating muscle foci. The relative subjectivity of this endpoint, as well as the applicability domain...article 2009
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de Looze, M.P. (author), Bosch, T. (author), van Dieën, J. (author), TNO Kwaliteit van Leven (author)Shoulder fatigue has been suggested to be a useful risk indicator for shoulder disorders in repetitive, low-force work tasks. In contrast to high-force or purely isometric tasks, it is unclear whether measurable fatigue develops in realistic low-force work. The question addressed in this review was: 'Is there evidence of objective signs of...article 2009
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van Dieën, J.H. (author), Putten, E.P. (author), Kingma, I. (author), de Looze, M.P. (author), TNO Kwaliteit van Leven (author)This study was designed to determine whether trunk extensor fatigue occurs during low-level activity and whether this is associated with a drop in muscle tissue oxygenation. Electromyography (EMG) feedback was used to impose constant activity in a part of the trunk extensor muscles. We hypothesized that electromyographic manifestations of...article 2009
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de Korte, E.M. (author), de Kraker, H. (author), Bongers, P.M. (author), van Lingen, P. (author), TNO Kwaliteit van Leven (author)To study the effects of a tactile feedback signal in a computer mouse on reduction of hovering behaviour and consequently on changes in muscle load, productivity, comfort and user friendliness, a comparative, experimental study with repeated measures was conducted. Fifteen subjects performed five trials with different mouse actions and a...article 2008
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Huysmans, M.A. (author), Hoozemans, M.J.M. (author), van der Beek, A.J. (author), de Looze, M.P. (author), van Dieën, J.H. (author), TNO Kwaliteit van Leven (author)It has been suggested that fatigue affects proprioception and consequently movement accuracy, the effects of which may be counteracted by increased muscle activity. To determine the effects of fatigue on tracking performance and muscle activity in the M. extensor carpi radialis (ECR), 11 female participants performed a 2-min tracking task with a...article 2008
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Kuijt-Evers, L.F.M. (author), Bosch, T. (author), Huysmans, M.A. (author), de Looze, M.P. (author), Vink, P. (author), TNO Kwaliteit van Leven (author)In the current study, the relationship between objective measurements and subjective experienced comfort and discomfort in using handsaws was examined. Twelve carpenters evaluated five different handsaws. Objective measures of contact pressure (average pressure, pressure area and pressure-time (P-t) integral) in static and dynamic conditions,...article 2007
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Visser, B. (author), van Dieën, J.H. (author), TNO Kwaliteit van Leven (author)A review of the literature on the pathophysiology of upper extremity muscle disorders (UEMDs) was performed. An overview is given of clinical findings and hypotheses on the pathogenesis of UEMDs. The literature indicates that disorders of muscle cells and limitations of the local circulation underlie UEMDs. However, these disorders identified do...article 2006
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Huysmans, M.A. (author), de Looze, M.P. (author), Hoozemans, M.J.M. (author), van der Beek, A.J. (author), van Dieën, J.H. (author), TNO Kwaliteit van Leven (author)The study was designed to determine the effect of joystick handle size and (display-control) gain at two levels of required task precision on performance and physical load on crane operators. Eight experienced crane operators performed a simulated crane operation task on a computer by use of a joystick with either a short or a large handle. The...article 2006
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Visser, B. (author), Nielsen, P.K. (author), de Kraker, H. (author), Smits, M. (author), Jensen, B.R. (author), Veeger, D. (author), van Dieën, J.H. (author), TNO Kwaliteit van Leven (author), KvL (author)The object of the current study was to determine whether static contraction of proximal musculature has an effect on the blood flow more distally in the upper extremity. Static contractions of muscles in the neck shoulder region at three levels (relaxed, shoulders elevated and shoulders elevated loaded with 4.95 kg each) were combined with...article 2006
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Hoozemans, M.J.M. (author), Visser, B. (author), Huysmans, M.A. (author), Speklé, E.M. (author), van Dieën, J.H. (author), TNO Arbeid (author)This paper presents an overview of theories concerning the development of RSI (repetitive strain injury), related to muscle disorders. Movement is a noisy process. The level of noise is affected by factors such as fatigue and psychosocial stress. In order for precision movements to be made in such situations, an increased level of muscle...article 2005
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Visser, B. (author), de Looze, M.P. (author), de Graaff, M.P. (author), van Dieën, J.H. (author)The objective of the present study was to gain insight into the effects of precision demands and mental pressure on the load of the upper extremity. Two computer mouse tasks were used: an aiming and a tracking task. Upper extremity loading was operationalized as the myo-electric activity of the wrist flexor and extensor and of the trapezius...article 2004
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Visser, B. (author), de Looze, M.P. (author), Veeger, D. (author), Douwes, M. (author), Groenesteijn, L. (author), de Korte, E. (author), van Dieën, J.H. (author), TNO Preventie en Gezondheid (author)High precision demands in manual tasks can be expected to cause more selective use of a part of the muscular synergy involved. To test this expectation, load sharing of the index finger and middle finger was investigated during a pinching task. Myoelectric activation of lower arm and neck-shoulder muscles was measured to see if overall level of...article 2003
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TNO Preventie en Gezondheid (author), Verkerke, G.J. (author), Lemmink, K.A.P.M. (author), Slagers, A.J. (author), Westhoff, M.H. (author), van Riet, G.A.J. (author), Rakhorst, G. (author)The mechanical performance, repeatability and comfort of the Quadrisotester, which assesses isometric knee extensor muscle strength, were examined. Twenty healthy subjects and 20 patients treated for unilateral anterior ligamenta cruciata insufficiency were tested. Intra-rater repeatability was determined by the testing and retesting of subjects...article 2003
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de Looze, M.P. (author), Steenhuizen, S. (author), Boeken-Kruger, M.C. (author), Baten, C.T.M. (author), Kingma, I. (author), van Dieën, J.H. (author)People who know the actual mass of an object to be lifted normally prepare themselves before attempting a lift to control the movement and to minimize low back loading. In this study, the trunk muscular reactions and low back torque were investigated in the situation in which the individual did not know the actual mass but only had some idea of...article 2000
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de Looze, M.P. (author), Groen, H. (author), Horemans, H. (author), Kingma, I. (author), van Dieën, J.H. (author), TNO Preventie en Gezondheid (author)In lifting, the abdominal muscles are thought to be activated to stabilize the spine. As a detrimental effect, they contribute to spinal compression. The existing literature is not conclusive about the biological relevance of this effect. From biological, mechanical and anatomical considerations it was hypothesised that the relative abdominal...article 1999
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