Searched for: subject:"Multicenter%5C+study"
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Boesveld, I.C. (author), Hermus, M.A.A. (author), van der Velden-Bollemaat, E.C. (author), Hitzert, M. (author), de Graaf, H.J. (author), Franx, A. (author), Wiegers, T.A. (author)
Objective: to determine the usability of a recently developed set of 30 structure and process birth centre quality indicators. Design: an explorative study using mixed-methods including literature, a survey, interviews and observations. The study is part of the Dutch Birth Centre Study. We first determined the measurability of birth centre...
article 2018
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Boesveld, I.C. (author), Bruijnzeels, M.A. (author), Hitzert, M. (author), Hermus, M.A.A. (author), van der Pal-de Bruin, K.M. (author), van den Akker-van Marle, M.E. (author), Steegers, E.A.P. (author), Franx, A. (author), de Vries, R.G. (author), Wiegers, T.A. (author)
Background: The goal of integrated care is to offer a continuum of care that crosses the boundaries of public health, primary, secondary, and tertiary care. Integrated care is increasingly promoted for people with complex needs and has also recently been promoted in maternity care systems to improve the quality of care. Especially when located...
article 2017
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van Gendt, A.W. (author), van der Pal, S.M. (author), Hermes, W. (author), Walther, F.J. (author), van der Pal-de Bruin, K.M. (author), de Groot, C.J.M. (author)
The aims of this study were to analyze reproductive outcomes of women and men born very preterm (gestational age <32 weeks) or with a very low birth weight (<1500 g) in 1983 in the Netherlands and to compare their reproductive outcomes with the total population at a similar age of 28 years. Young adults who were born after a pregnancy...
article 2015
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Raiten, D.J. (author), Sakr Ashour, F.A. (author), Ross, A.C. (author), Meydani, S.N. (author), Dawson, H.D. (author), Stephensen, C.B. (author), Brabin, B.J. (author), Suchdev, P.S. (author), van Ommen, B. (author), Ahluwalia, N. (author), Ahmed, T. (author), Allen, L. (author), Beck, M. (author), Blanchard, H. (author), Brindle, E. (author), Brown, K. (author), Calder, P. (author), Checkley, W. (author), Claycombe, K. (author), Coles, C. (author), Esamai, F. (author), Friis, H. (author), Gardner, E. (author), Grinspoon, S. (author), Guerrant, R. (author), Hellerstein, M. (author), Hunt, J. (author), King, J. (author), Klasing, K. (author), Kramer, B. (author), Koski, K. (author), Northrop-Clewes, C. (author), Pfeiffer, C. (author), Prentice, A. (author), Ramirez-Zea, M. (author), van Rheenan, P. (author), Rink, L. (author), Srinivasa, S. (author), Benn, C.S. (author), Stephensen, C. (author), Suchdev, P. (author), Sullivan, K. (author), Thurnham, D. (author), Varadhan, R. (author), Van Der Ven, A. (author), Walston, J. (author), Xia, J. (author)
An increasing recognition has emerged of the complexities of the global health agenda-specifically, the collision of infections and noncommunicable diseases and the dual burden of over- and undernutrition. Of particular practical concern are both 1) the need for a better understanding of the bidirectional relations between nutritional status and...
article 2015
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van den Bemt, P.M.L.A. (author), van der Schrieck-De Loos, E.M. (author), van der Linden, C. (author), Theeuwes, A.M.L.J. (author), Pol, A.G. (author)
Objectives To investigate the effect of pharmacy-based medication reconciliation on the frequency of unintentional medication discrepancies in acutely admitted individuals aged 65 and older. Design Multicenter intervention study with pre-post design. Setting Twelve Dutch hospitals. Participants One thousand five hundred forty-three individuals...
article 2013
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Preller, L. (author), van den Bosch, L.M.C. (author), van den Brandt, P.A. (author), Kauppinen, T. (author), Goldbohm, R.A. (author), TNO Kwaliteit van Leven (author)
Objectives: The lung cancer carcinogenicity of crystalline silica dust remains the subject of discussion. Epidemiological evidence is based on occupational cohort studies and population-based case-control studies. The aim of this study was to assess associations between male lung cancer risk and silica exposure in a population-based cohort study...
article 2010
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Chanteranne, B. (author), Branca, F. (author), Kardinaal, A. (author), Wahala, K. (author), Braesco, V. (author), Ladroite, P. (author), Brouns, F. (author), Coxam, V. (author), TNO Kwaliteit van Leven (author)
The estrogenic effects of soy isoflavones (IF) on symptoms of menopause are of particular interest. The aim of the present study was to improve compliance of IF in two IF-enriched foods providing the same IF circulating levels in postmenopausal women. Forty-two healthy postmenopausal women (mean age: 53.28 years) were recruited for a randomized,...
article 2008
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Grote, F.K. (author), van Dommelen, P. (author), Oostdijk, W. (author), de Muinck Keizer-Schrama, S.M.P.F. (author), Verkerk, P.H. (author), Wit, J.M. (author), van Buuren, S. (author), TNO Kwaliteit van Leven (author)
Objective: To establish evidence based guidelines for growth monitoring on a population basis. Study design: Several auxological referral criteria were formulated and applied to longitudinal growth data from four different patient groups, as well as three samples from the general population. Results: Almost 30% of pathology can be detected by...
article 2008
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Bergheanu, S.C. (author), Reijmers, T. (author), Zwinderman, A.H. (author), Bobeldijk, I. (author), Ramaker, R. (author), Liem, A.-H. (author), van der Greef, J. (author), Hankemeier, T. (author), Jukema, J.W. (author), TNO Kwaliteit van Leven (author)
Objective: Lipid profiling (lipidomics) may be useful in revealing detailed information with regard to the effects on lipid metabolism, the cardiovascular risk and to differentiate between therapies. The aims of the present study were to: (1) analyze in depth the lipid changes induced by rosuvastatin and atorvastatin at different dosages; (2)...
article 2008
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Norris, L.A. (author), Brosnan, J. (author), Bonnar, J. (author), Conard, J. (author), Kluft, C. (author), Hellgren, M. (author), TNO Kwaliteit van Leven (author)
Epidemiological studies have shown that hormone therapy (HT) increases the risk of venous thromboembolism in post menopausal women. The mechanism of this increased risk is unknown; however, activation of the haemostatic system is known to contribute to the pathogenesis of venous thromboembolism. In post-menopausal women the estrogen /progestogen...
article 2008
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van der Pal, S.M. (author), Maguire, C.M. (author), Bruil, J. (author), le Cessie, S. (author), Wit, J.M. (author), Walther, F.J. (author), Veen, S. (author), TNO Kwaliteit van Leven (author)
Background: In the context of a growing interest in developmental care (DC) this study explores the effect of the basic elements of DC and the additional effect of the individual approach of the Newborn Individualized Developmental Care and Assessment Program (NIDCAP) on the health-related quality of life (HRQoL) of very preterm infants at 1...
article 2008
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Schouten, L.J. (author), Rivera, C. (author), Hunter, D.J. (author), Spiegelman, D. (author), Adami, H.-O. (author), Arslan, A. (author), Beeson, W.L. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Folsom, A.R. (author), Fraser, G.E. (author), Freudenheim, J.L. (author), Goldbohm, R.A. (author), Hankinson, S.E. (author), Lacey Jr., J.V. (author), Leitzmann, M. (author), Lukanova, A. (author), Marshall, J.R. (author), Miller, A.B. (author), Patel, A.V. (author), Rodriguez, C. (author), Rohan, T.E. (author), Ross, J.A. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)
Background: Although many studies have investigated the association between anthropometry and ovarian cancer risk, results have been inconsistent. Methods: The associations of height, body mass index (BMI), and ovarian cancer risk were examined in a pooled analysis of primary data from 12 prospective cohort studies from North America and Europe....
article 2008
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Bongaerts, B.W.C. (author), de Goeij, A.F.P.M. (author), de Vogel, S. (author), van den Brandt, P.A. (author), Goldbohm, R.A. (author), Weijenberg, M.P. (author), TNO Kwaliteit van Leven (author)
High alcohol consumption is related to colorectal cancer (CRC). Our objective was to study associations between alcohol consumption and risk of CRC according to characteristics of aetiological pathways: the chromosomal instability (CIN) and the microsatellite instability (MIN) pathway. We classified CIN+ tumours (tumours with either a truncating...
article 2007
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Sluijter, J.P.G. (author), Pulskens, W.P.C. (author), Schoneveld, A.H. (author), Velema, E. (author), Strijder, C.F. (author), Moll, F. (author), de Vries, J.P. (author), Verheijen, J. (author), Hanemaaijer, R. (author), de Kleijn, D.P.V. (author), Pasterkamp, G. (author), TNO Kwaliteit van Leven (author)
Background and Purpose - We studied matrix metalloproteinases (MMP) 2, 8, and 9 and extracellular matrix metalloproteinase inducer (EMMPRIN) levels in relation to carotid atherosclerotic plaque characteristics. Methods - Carotid atherosclerotic plaques (n=150) were stained and analyzed for the presence of collagen, smooth muscle cell (SMC), and...
article 2006
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Vogelvang, T.E. (author), Mijatovic, V. (author), Kenemans, P. (author), Emeis, J.J. (author), Heijst, J.A. (author), van der Mooren, M.J. (author), TNO Preventie en Gezondheid (author)
Objective: To investigate the short-term effects of HMR 3339, a novel selective estrogen receptor modulator, on markers of coagulation and fibrinolysis. Study design: In a multicenter, 14-week, randomized, placebo-controlled, double-blind, dose-ranging study, healthy postmenopausal women received daily placebo (n = 22), HMR 3339 2.5 mg (n = 25),...
article 2005
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Beulens, J.W.J. (author), Stolk, R.P. (author), van der Schouw, Y.T. (author), Grobbee, D.E. (author), Hendriks, H.F.J. (author), Bots, M.L. (author), TNO Kwaliteit van Leven (author)
OBJECTIVE - This study aimed to investigate the relation between alcohol consumption and type 2 diabetes among older women. RESEARCH DESIGN AND METHODS - Between 1993 and 1997, 16,330 women aged 49-70 years and free from diabetes were enrolled in one of the Dutch Prospect-EPIC (European Prospective Study Into Cancer and Nutrition) cohorts and...
article 2005
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Hille, E.T.M. (author), Elbertse, L. (author), Bennebroek Gravenhorst, J. (author), Brand, R. (author), Verloove-Vanhorick, S.P. (author), TNO Kwaliteit van Leven (author)
Objective. To assess the effect of demographic and neonatal risk factors and outcome at the last available assessment on the probability of full responders, postal responders (those who only responded to the mailed questionnaire), or nonresponders in a follow-up study of 19-year-old adolescents who were born as preterm infants. Design. The 19...
article 2005
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van den Hauwe, O. (author), Campbell, K. (author), Crooks, S.R.H. (author), Schilt, R. (author), van Peteghem, C.H. (author), TNO Kwaliteit van Leven (author)
Within the framework of a European Union (EU) research project entitled "Food Safety Screening: Synthetic Glucocorticoids (QLK1-1999-00122)," an international interlaboratory ring test was organized to compare and evaluate different liquid chromatography/mass spectrometry (LC/MS) confirmatory methods that are applied in European monitoring...
article 2005
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van Tijn, D.A. (author), de Vijlder, J.J.M. (author), Verbeeten Jr., B. (author), Verkerk, P.H. (author), Vulsma, T. (author), TNO Preventie en Gezondheid (author)
Due to the high frequency of concurrent pituitary hormone deficiencies, congenital hypothyroidism (CH) of central origin (CH-C) is a life-threatening disorder. Yet only a minority of these patients are detected by neonatal CH screening programs worldwide. We conducted a prospective multicenter study involving a 2-yr cohort of neonatally...
article 2005
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Bousquet, J. (author), Demarteau, N. (author), Mullol, J. (author), van den Akker-van Marle, M.E. (author), van Ganse, E. (author), Bachert, C. (author), TNO Preventie en Gezondheid (author)
Background: Allergic rhinitis was recently classified by the ARIA guidelines as persistent or intermittent. Levocetivizine was shown to improve symptoms and health-related quality of life of patients with persistent allergic rhinitis in the XPERTâ„¢ study, a 6-month randomized double blind placebo-controlled trial. Objective: To assess the total...
article 2005
Searched for: subject:"Multicenter%5C+study"
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