Searched for: subject:"Monitoring"
(1 - 20 of 573)

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Noort, D. (author), Hulst, A.G. (author), Fidder, A. (author), van Gurp, R.A. (author), de Jong, L.P.A. (author), Benschop, H.P. (author), Prins Maurits Laboratorium TNO (author)
The development of procedures for retrospective detection and quantitation of exposure to phosgene, based on adducts to hemoglobin and albumin, is described. Upon incubation of human blood with [14C]phosgene (0-750 μM), a significant part of radioactivity (0-13%) became associated with globin and albumin. Upon Pronase digestion of globin, one of...
article 2000
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Schmidt, R.D.O. (author), Sadre, R. (author), Sperotto, A. (author), van den Berg, H. (author), Pras, A. (author)
Link dimensioning is used by network operators to properly provision the capacity of their network links. Proposed methods for link dimensioning often require statistics, such as traffic variance, that need to be calculated from packet-level measurements. In practice, due to increasing traffic volume, operators deploy packet sampling techniques...
article 2015
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Tuma, M. (author), Rorbech, V. (author), Prior, M. (author), Igel, C. (author)
We designed and jointly optimized an integrated signal processing chain for detection and classification of long-range passive-acoustic underwater signals recorded by the global geophysical monitoring network of the Comprehensive Nuclear-Test-Ban Treaty Organization. Starting at the level of raw waveform data, a processing chain of signal...
article 2016
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Chadwick, R.A. (author), Noy, D. (author), Arts, R. (author), Eiken, O. (author), TNO Bouw en Ondergrond (author)
Since its inception in 1996, the CO2 injection operation at Sleipner has been monitored by 3D time-lapse seismic surveys. Striking images of the CO2 plume have been obtained, showing a multi-tier feature of high reflectivity, interpreted as arising from a number of thin layers of CO2 trapped beneath thin, intra-reservoir mudstones. The topmost...
article 2009
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Rosendal, H. (author), Vondeling, H. (author), de Witte, L.P. (author), Hutubessy, R.C.W. (author), van Beekum, W.T. (author), Heine, R.J. (author)
Objective. Assessing whether the initiation of insulin therapy in patients with diabetes mellitus type 2 can be delivered as effectively in a structured transmural care model as in the more usual outpatients structure. Design. Retrospective comparative cohort study. Method. In 1997 data were collected from 52 patients with diabetes mellitus type...
article 2002
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Noort, D. (author), Hulst, A.G. (author), Jansen, R. (author), Prins Maurits Laboratorium TNO (author)
Covalent binding of various clinically important nitrogen mustards to the cysteine-34 residue of human serum albumin, in vitro and in vivo, is demonstrated. A rapid method for detection of these adducts is presented, based on liquid chromatography-tandem mass spectrometry analysis of the adducted tripeptide Cys*-Pro-Phe after digestion of the...
article 2002
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de Jong-de Vos Van Steenwijk, C.C.E. (author), Wieling, W. (author), Harms, M.P.M. (author), Wesseling, K.H. (author), TNO Biomedical Instrumentation (author)
1. Fainting is a common phenomenon in young subjects, but the final events before the actual faint are not well known. The aim of the present study was to study the inter-individual variability of haemodynamic events associated with near-fainting in children and teenagers. 2. Sixty-eight healthy subjects (aged 6-16 years) performed a 70°tilt-up...
article 1997
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Damsten, M.C. (author), Commandeur, J.N.M. (author), Fidder, A. (author), Hulst, A.G. (author), Touw, D. (author), Noort, D. (author), Vermeulen, N.P.E. (author), TNO Defensie en Veiligheid (author)
Covalent binding of reactive electrophilic intermediates to proteins is considered to play an important role in the processes leading to adverse drug reactions and idiosyncratic drug reactions. Consequently, both for the discovery and the development of new drugs, there is a great interest in sensitive methodologies that enable the detection of...
article 2007
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Pyayt, A.L. (author), Mokhov, I.I. (author), Lang, B. (author), Krzhizhanovskaya, V.V. (author), Meijer, R.J. (author)
More and more natural disasters are happening every year: floods, earthquakes, volcanic eruptions, etc. In order to reduce the risk of possible damages, governments all around the world are investing into development of Early Warning Systems (EWS) for environmental applications. The most important task of the EWS is identification of the onset...
article 2011
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Anderson, D. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO BIBRA (author)
Butadiene (BD) and its 2-methyl analogue, isoprene, have been extensively studied in animals and BD in population studies. Both chemicals are metabolised by liver cytochrome P450 dependent monogenases to monoepoxide and diepoxide intermediates. The diepoxide intermediates of both compounds were mutagenic in Salmonella typhimurium. However,...
article 2001
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Tielemans, E. (author), Bretveld, R. (author), Schinkel, J. (author), de Wendel van - Joode, B. (author), Kromhout, H. (author), Gerritsen-Ebben, R. (author), Roeleveld, N. (author), Preller, L. (author), TNO Kwaliteit van Leven (author)
The aim of this study was to assess exposure to pesticides for a longitudinal epidemiological study on adverse reproduction effects among greenhouse workers. Detailed information on pesticide use among greenhouse workers was obtained on a monthly basis through self-administered questionnaires and subsequent workplace surveys. Questionnaires were...
article 2007
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Hertsenberg, S. (author), Brouwer, D. (author), Lurvink, M. (author), Rubingh, C. (author), Rijnders, E. (author), Tielemans, E. (author), TNO Kwaliteit van Leven (author)
Self-assessment of exposure (SAE) refers to any exposure assessment methodology wherein the worker takes an active role in establishing his or her exposure status. The objective of this study was to investigate the reliability and feasibility of SAE approaches among shoe repair workers collecting exposure data over a 3 month period. This study...
article 2007
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Kompier, M. (author), de Gier, E. (author), Smulders, P. (author), Draaisma, D. (author), TNO Preventie en Gezondheid (author)
A comparative inventory of regulations, policies and practices in The Netherlands, Sweden, UK, Germany and France with regard to the prevention of work stress was carried out. In each country data were collected by means of interviews with key informants and through exploring relevant documents and literature. It was found that Sweden. The...
article 1994
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Omboni, S. (author), Parati, G. (author), Castiglioni, P. (author), di Rienzo, M. (author), Imholz, B.P.M. (author), Langewouters, G.J. (author), Wesseling, K.H. (author), Mancia, G. (author), TNO Biomedical Instrumentation (author)
Portapres is a noninvasive, beat-to-beat finger blood pressure (BP) monitor that has been shown to accurately estimate 24-hour intra-arterial BP at normal and high BPs. However, no information is available on the ability of this device to accurately track ambulatory BP variability. In 20 ambulatory normotensive and hypertensive subjects, we...
article 1998
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Wessels, P.W. (author), Basten, T.G.H. (author)
An increase in public awareness of noise pollution and the impact of noise on human health has led to the need for enhanced insight in complex noise situations. This insight is commonly obtained either by brief measurements or by evaluation of a simplified acoustic model. Both of these approaches however have limitations in complex noise...
article 2016
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de Kluizenaar, Y. (author), Kuijpers, E. (author), Eekhout, I. (author), Voogt, M. (author), Vermeulen, R.C.H. (author), Hoek, G. (author), Sterkenburg, R.P. (author), Pierik, F.H. (author), Duyzer, J.H. (author), Meijer, E.W. (author), Pronk, A. (author)
Particulate matter exposure may cause adverse health effects. Although ultrafine particulate matter (UFP) is hypothesised to be particularly health relevant, the number of studies into personal UFP exposure is limited. Aim To increase insight where and when most UFP exposure occurs, in terms of exposure levels and peaks in microenvironments,...
article 2017
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van Hemmen, J.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
In a project granted by DG XI of the European Commission, it is attempted to collate experimental and theoretical data on human (workers and consumers) exposure assessment to biocidal products, and to outline the methodology for sampling and measurement. On the basis of the available evidence, approaches are presented for the exposure assessment...
article 1999
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Velikova, M. (author), Lucas, P.J.F. (author), van der Heijden, M. (author)
Cost-effective mobile healthcare must consider not only technological performance but also the division of responsibilities between the patient and care provider, the context of the patient’s condition, and ways to implement patient decision support and tailored interaction.
article 2015
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Werlen, C. (author), Jaspers, M.C.M. (author), van der Meer, J.R. (author), TNO Voeding (author)
Genetically constructed microbial biosensors for measuring organic pollutants are mostly applied in aqueous samples. Unfortunately, the detection limit of most biosensors is insufficient to detect pollutants at low but environmentally relevant concentrations. However, organic pollutants with low levels of water solubility often have significant...
article 2004
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Lotens, W.A. (author), Wammes, L.J.A. (author)
An experiment was carried out to measure the vapour resistance of two-layer clothing ensembles as a function of air permeability of the outer layer, open or closed apertures, wind, and walking, both for the total ensemble and for the outer garment alone. Six subjects walked on a treadmill (0.0, 2.5, and 5 km.h-1) which was placed in a wind...
article 1993
Searched for: subject:"Monitoring"
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