Searched for: subject:"Monitoring"
(1 - 20 of 24)

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Tielemans, E. (author), Schneider, T. (author), Goede, H. (author), Tischer, M. (author), Warren, N. (author), Kromhout, H. (author), van Tongeren, M. (author), van Hemmen, J. (author), Cherrie, J.W. (author), TNO Kwaliteit van Leven (author)
The present paper proposes a source-receptor model to schematically describe inhalation exposure to help understand the complex processes leading to inhalation of hazardous substances. The model considers a stepwise transfer of a contaminant from the source to the receptor. The conceptual model is constructed using three components, i.e. (i) the...
article 2008
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Money, C.D. (author), van Hemmen, J.J. (author), Vermeire, T.G. (author), TNO Kwaliteit van Leven (author)
The primary process established by the European Commission to address the science needed to define key REACH concepts and to help rationally implement REACH's ambitions is enshrined in a series of activities known as the REACH Implementation Projects (RIPs). These are projects that aim to define the methodology that could be used, and present...
article 2007
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van de Sandt, J.J.M. (author), Dellarco, M. (author), van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
Exposure scenarios form an essential basis for chemical risk assessment reports under the new EU chemicals regulation REACH (Registration, Evaluation, Authorisation and restriction of Chemicals). In case the dermal route of exposure is predominant, information on both exposure and dermal bioavailability is necessary for a proper risk assessment....
article 2007
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Pronk, A. (author), Tielemans, E. (author), Skarping, G. (author), Bobeldijk, I. (author), van Hemmen, J. (author), Heederik, D. (author), Preller, L. (author), TNO Kwaliteit van Leven (author)
As part of a large-scale epidemiological study, occupational isocyanate exposure was assessed in spray-painting environments. The aim was to assess which compounds contribute to isocyanate exposure in car body repair shops and industrial painting companies, and to identify tasks with high risk of isocyanate exposure. Mainly personal task-based...
article 2006
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Marquart, H. (author), Warren, N.D. (author), Laitinen, J. (author), van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
Dermal exposure needs to be addressed in regulatory risk assessment of chemicals. The models used so far are based on very limited data. The EU project RISKOFDERM has gathered a large number of new measurements on dermal exposure to industrial chemicals in various work situations, together with information on possible determinants of exposure....
article 2006
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van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
article 2006
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Warren, N.D. (author), Marquart, H. (author), Christopher, Y. (author), Laitinen, J. (author), van Hemmen, J.J. (author), TNO Kwaliteit van Leven (author)
The regulatory risk assessment of chemicals requires the estimation of occupational dermal exposure. Until recently, the models used were either based on limited data or were specific to a particular class of chemical or application. The EU project RISKOFDERM has gathered a considerable number of new measurements of dermal exposure together with...
article 2006
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van Wendel de Joode, B. (author), Vermeulen, R. (author), van Hemmen, J.J. (author), Fransman, W. (author), Kromhout, H. (author), TNO Kwaliteit van Leven (author)
Background: The authors recently developed a Dermal Exposure Assessment Method (DREAM), an observational semiquantitative method to assess dermal exposures by systematically evaluating exposure determinants using pre-assigned default values. Aim: To explore the accuracy of the DREAM method by comparing its estimates with quantitative dermal...
article 2005
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Brouwer, D.H. (author), de Pater, N.A.J. (author), Zomer, C. (author), Lurvink, M.W.M. (author), van Hemmen, J.J. (author), TNO Kwaliteit van Leven TNO Defensie en Veiligheid (author)
The concept of occupational air requirement (OAR), representing the quantity of air required to dilute the vapor concentration in the work environment resulting from 11 product to a concentration below the occupational exposure limit (OEL), was considered to have potential to discriminate between paints that can and cannot be used safely. The...
article 2005
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Kromhout, H. (author), Fransman, W. (author), Vermeulen, R. (author), Roff, M. (author), van Hemmen, J.J. (author), TNO Voeding (author)
Introduction: The RISKOFDERM project collected task-based estimates of potential dermal exposure from a wide range of industries and services from around Europe. A formal statistical analysis was carried out to explore the main components of variability in dermal exposure levels. The central research question was to what extent dermal exposure...
article 2004
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Brouwer, D.H. (author), Boeniger, M.F. (author), van Hemmen, J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Hand wash and skin wipes are major techniques that have been used for dermal exposure sampling. Both techniques remove chemicals either deposited on or transferred to the skin contaminant layer by a combination of chemical and mechanical actions. The paper overviews identified methods and techniques, with emphasis on sampling parameters and...
article 2000
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Brouwer, D.H. (author), Lansink, C.M. (author), Cherrie, J.W. (author), van Hemmen, J.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The range of dermal exposure to non-volatile compounds during spray painting was studied in a semi-experimental study involving three enterprises and 12 painters. A fluorescent tracer was added to the paint and deposition of the tracer on clothing and uncovered parts of the skin was assessed using video imaging and processing techniques. A...
article 2000
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van Hemmen, J.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
In a project granted by DG XI of the European Commission, it is attempted to collate experimental and theoretical data on human (workers and consumers) exposure assessment to biocidal products, and to outline the methodology for sampling and measurement. On the basis of the available evidence, approaches are presented for the exposure assessment...
article 1999
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Benford, D.J. (author), Cocker, J. (author), Sartorelli, P. (author), Schneider, T. (author), van Hemmen, J. (author), Firth, J.G. (author), Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author)
To evaluate risk from dermal exposure, the amount of material on the skin must first be measured. The potential for dermal uptake must then be assessed for the potential health effects from systemic exposure. No standard methods exist for studying these processes, and published data are not comparable because of the different techniques used....
article 1999
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Bos, P.M.J. (author), Brouwer, D.H. (author), Stevenson, H. (author), Hoogendoorn, L. (author), Boogaard, P.J. (author), de Kort, W.L.A.M. (author), van Hemmen, J.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Objective. To evaluate two different techniques for assessing dermal exposure to 4,4'-methylene dianiline (MDA) in a field study. The results were used to test the applicability of a recently proposed quantitative dermal occupational exposure limit (DOEL) for MDA in a workplace scenario. Methods. For two consecutive weeks six workers were...
article 1998
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de Vreede, J.A.F. (author), den Boeft, J. (author), van Hemmen, J.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
In agricultural areas where greenhouses and dwellings are intermixed, the general population as well as the professional applicators may be exposed to pesticides. In a field study on Crete, exposure to methyl bromide during soil fumigation was assessed. Exposure of applicators (both contractors and farmers) were measured with personal air...
article 1998
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van Leeuwen, C.J. (author), Bro-Rasmussen, F. (author), Feijtel, T.C.J. (author), Arndt, R. (author), Bussian, B.M. (author), Calamari, D. (author), Glynn, P. (author), Grandy, N.J. (author), Hansen, B. (author), van Hemmen, J.J. (author), Hurst, P. (author), King, N. (author), Koch, R. (author), Müller, M. (author), Solbé, J.F. (author), Speijers, G.A.B. (author), Vermeire, T. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
An evaluation was made of the recently developed risk assessment methodologies for new and existing chemicals in the European Communities. The evaluation also included the methodologies to prioritize chemicals and procedures for risk management, i.e., the (draft) guidance document for the development of strategies for risk reduction. The way in...
article 1996
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van Hemmen, J.J. (author), Brouwer, D.H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The methods for the dermal exposure assessment vary in their complexity and are in some sense complementary to each other. The most easy-to-use methods involve a pseudo-skin-approach, such as gloves and removal by washing. In some cases generic modelling appears to be possible. The experimental methods can indicate and even quantitate the...
article 1995
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van Hemmen, J.J. (author), Medisch Biologisch Laboratorium TNO (author)
The health risk to the agricultural worker using pesticides is important for registration procedures since during mixing, loading and application he or she handles undiluted as well as diluted pesticide formulations. Furthermore, exposure may occur during daily activities in the crop (e.g. harvesting). Possible exposure may reach levels that...
article 1993
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Geuskens, R.B.M. (author), van der Klaauw, M.M. (author), van der Tuin, J. (author), van Hemmen, J.J. (author), Medisch Biologisch Laboratorium TNO (author)
A study of the health hazards for workers exposed to styrene in the Dutch glass-reinforced plastics industry was undertaken. The open mould techniques of filament winding, spraying and hand laminating were chosen for study because exposure of workers using them was expected to be high. Occupational hygiene surveys were conducted in four plants....
article 1992
Searched for: subject:"Monitoring"
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