Searched for: subject%3A%22Mitochondrial%255C%2BDNA%22
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Ghosh, M. (author), Janssen, L. (author), Martens, D.S. (author), Öner, D. (author), Vlaanderen, J. (author), Pronk, A. (author), Kuijpers, E. (author), Vermeulen, R. (author), Nawrot, T.S. (author), Godderis, L. (author), Hoet, P.H. (author)
Carbon nanotubes (CNTs) except MWCNT-7 have been classified as Group 3 ["Not classifiable as to its carcinogenicity to humans"] by the IARC. Despite considerable mechanistic evidence in vitro/in vivo, the classification highlights a general lack of data, especially among humans. In our previous study, we reported epigenetic changes in the MWCNT...
article 2020
Martin, A.M. (author), Hammond, E. (author), Nolan, D. (author), Pace, C. (author), Den Boer, M. (author), Taylor, L. (author), Moore, H. (author), Martinez, O.P. (author), Christiansen, F.T. (author), Mallal, S. (author), TNO Preventie en Gezondheid (author)
Nucleoside reverse-transcriptase inhibitor (NRTI) therapy for human immunodeficiency virus (HIV) infection has been associated with mitochondrial DNA (mtDNA) polymerase-γ inhibition and subsequent mtDNA depletion. Effects on mtDNA mutation, although suggested by critical involvement of polymerase-γ in DNA-repair reactions, are unknown. In the...
article 2003