- document
-
Ghosh, M. (author), Janssen, L. (author), Martens, D.S. (author), Öner, D. (author), Vlaanderen, J. (author), Pronk, A. (author), Kuijpers, E. (author), Vermeulen, R. (author), Nawrot, T.S. (author), Godderis, L. (author), Hoet, P.H. (author)Carbon nanotubes (CNTs) except MWCNT-7 have been classified as Group 3 ["Not classifiable as to its carcinogenicity to humans"] by the IARC. Despite considerable mechanistic evidence in vitro/in vivo, the classification highlights a general lack of data, especially among humans. In our previous study, we reported epigenetic changes in the MWCNT...article 2020
- document
-
Martin, A.M. (author), Hammond, E. (author), Nolan, D. (author), Pace, C. (author), Den Boer, M. (author), Taylor, L. (author), Moore, H. (author), Martinez, O.P. (author), Christiansen, F.T. (author), Mallal, S. (author), TNO Preventie en Gezondheid (author)Nucleoside reverse-transcriptase inhibitor (NRTI) therapy for human immunodeficiency virus (HIV) infection has been associated with mitochondrial DNA (mtDNA) polymerase-γ inhibition and subsequent mtDNA depletion. Effects on mtDNA mutation, although suggested by critical involvement of polymerase-γ in DNA-repair reactions, are unknown. In the...article 2003