Searched for: subject%3A%22Microbiome%22
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Lee, J.K.W. (author), Tan, B. (author), Kingma, B.R.M. (author), Haman, F. (author), Epstein, Y. (author)
Exposure to extreme environmental heat or cold during military activities can impose severe thermal strain, leading to impairments in task performance and increasing the risk of exertional heat (including heat stroke) and cold injuries that can be life-threatening. Substantial individual variability in physiological tolerance to thermal stress...
article 2023
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Fluitman, K.S. (author), Wijdeveld, M. (author), Davids, M. (author), van Ruiten, C.C. (author), Reinders, I. (author), Wijnhoven, H.A.H. (author), Keijser, B.J.F. (author), Visser, M. (author), Nieuwdorp, M. (author), IJzerman, R.G. (author)
Expert groups argue to raise the recommended daily allowance for protein in older adults from 0.8 to 1.2 g/kg/day to prevent undernutrition. However, protein is thought to increase satiety, possibly through effects on gut microbiota and central appetite regulation. If true, raising daily protein intake may work counterproductively. In a...
article 2023
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van Mierlo, M.M.F. (author), Pardo, L.M. (author), Fieten, K.B. (author), van den Broek, T.J. (author), Schuren, F.H.J. (author), van Geel, M. (author), Pasmans, S.G.M.A. (author)
Background: Interactions between the skin barrier, immune system, and microbiome underlie the development of atopic dermatitis (AD). Objective: To investigate the skin and nasal microbiome in relation to filaggrin gene (FLG) mutations. Methods: A cross-sectional study including 77 children with difficult-to-treat AD. The entire encoding region...
article 2022
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Pinart, M. (author), Dötsch, A. (author), Schlicht, K. (author), Laudes, M. (author), Bouwman, J. (author), Forslund, S.F. (author), Pischon, T. (author), Nimptsch, K. (author)
Whether the gut microbiome in obesity is characterized by lower diversity and altered composition at the phylum or genus level may be more accurately investigated using high-through-put sequencing technologies. We conducted a systematic review in PubMed and Embase including 32 cross-sectional studies assessing the gut microbiome composition by...
article 2022
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Agamennone, V. (author), Abuja, P.M. (author), Basic, M. (author), De Angelis, M. (author), Gessner, A. (author), Keijser, B. (author), Larsen, M. (author), Pinart, M. (author), Nimptsch, K. (author), Pujos-Guillot, E. (author), Schlicht, K. (author), Sharon, I. (author), Untersmayr, E. (author), Laudes, M. (author), ischon, T. (author), Bouwman, J. (author)
Studies indicate that the intestinal microbiota influences general metabolic processes in humans, thereby modulating the risk of chronic diseases such as type 2 diabetes, allergy, cardiovascular disease, and colorectal cancer (CRC). Dietary factors are also directly related to chronic disease risk, and they affect the composition and function of...
article 2022
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Selberherr, E. (author), Grau, J.H. (author), Meixner, M. (author), Liere, K. (author), Ercolini, D. (author), de Filippo, C. (author), Caderni, G. (author), Brigidi, P. (author), Turroni, S. (author)
The core microbiome, which refers to a set of consistent microbial features across populations, is of major interest in microbiome research and has been addressed by numerous studies. Understanding the core microbiome can help identify elements that lead to dysbiosis, and lead to treatments for microbiome-related health states. However, defining...
article 2022
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van Erp, J.B.F. (author)
Implicit physiological measures such as heart rate and skin conductance convey information about someone's cognitive or affective state. Currently, gastrointestinal (GI) tract-based markers are not yet considered while both the organs involved as well as the microbiota populating the GI tract are bidirectionally connected to the brain and have a...
article 2022
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Sharon, I. (author), Quijada, N.M. (author), Pasolli, E. (author), Fabbrini, M. (author), Vitali, F. (author), Agamennone, V. (author), Dötsch, A. (author), Selberherr, E. (author), Grau, J.H. (author), Meixner, M. (author), Liere, K. (author), Ercolini, D. (author), de Filippo, C. (author), Caderni, G. (author), Brigidi, P. (author), Turroni, S. (author)
The core microbiome, which refers to a set of consistent microbial features across populations, is of major interest in microbiome research and has been addressed by numerous studies. Understanding the core microbiome can help identify elements that lead to dysbiosis, and lead to treatments for microbiome-related health states. However, defining...
article 2022
document
Pinart, M. (author), Nimptsch, K. (author), Forslund, S.F. (author), Schlicht, K. (author), Gueimonde, M. (author), Brigidi, P. (author), Turroni, S. (author), Ahrens, W. (author), Hebestreit, A. (author), Wolters, M. (author), Dötsch, A. (author), Nöthlings, U. (author), Oluwagbemigun, K. (author), Cuadrat, R.R.C. (author), Schulze, M.B. (author), Standl, M. (author), Schloter, M. (author), De Angelis, M. (author), Iozzo, P. (author), Guzzardi, M.G. (author), Vlaemynck, G. (author), Penders, J (author), Jonkers, D.M.A.E. (author), Stemmer, M. (author), Chiesa, G. (author), Cavalieri, D. (author), De Filippo, C. (author), Ercolini, D. (author), De Filippis, F. (author), Ribet, D. (author), Achamrah, N. (author), Tavolacci, M.P. (author), Déchelotte, P. (author), Bouwman, J. (author), Laudes, M. (author), Pischon, T. (author)
In any research field, data access and data integration are major challenges that even large, well-established consortia face. Although data sharing initiatives are increasing, joint data analyses on nutrition and microbiomics in health and disease are still scarce. We aimed to identify observational studies with data on nutrition and gut...
article 2021
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Pagan, L. (author), Ederveen, R.A.M. (author), Huisman, B.W. (author), Schoones, J.W. (author), Zwittink, R.D. (author), Schuren, F.H.J. (author), Rissmann, R. (author), Piek, J.M.J. (author), van Poelgeest, M.I.E. (author)
The link between cancer and the microbiome is a fast-moving field in research. There is little knowledge on the microbiome in ((pre)malignant) conditions of the vulvar skin. This systematic review aims to provide an overview of the literature regarding the microbiome composition of the healthy vulvar skin and in (pre)malignant vulvar disease....
article 2021
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Adams, S.H. (author), Anthony, J.C. (author), Carvajal, R. (author), Chae, L. (author), Khoo, C.S.H. (author), Latulippe, M.E. (author), Matusheski, N.V. (author), McClung, H.L. (author), Rozga, M. (author), Schmid, C.H. (author), Wopereis, S. (author), Yan, W. (author)
Personalized nutrition (PN) approaches have been shown to help drive behavior change and positively influence health outcomes. This has led to an increase in the development of commercially available PN programs, which utilize various forms of individual-level information to provide services and products for consumers. The lack of a well...
article 2020
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Griffiths, J.C. (author), de Vries, J. (author), McBurney, M.I. (author), Wopereis, S. (author), Serttas, S. (author), Marsman, D.S. (author)
Commonly, it is the end of life when our health is deteriorating, that many will make drastic lifestyle changes to improve their quality of life. However, it is increasingly recognized that bringing good health-promoting behaviors into practice as early in life as possible has the most significant impact across the maximal healthspan. The WHO...
article 2020
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van Mierlo, M.M.F. (author), Totté, J.E.E. (author), Fieten, K.B. (author), van den Broek, T.J. (author), Schuren, F.H.J. (author), Pardo, L.M. (author), Pasmans, S.G.M.A. (author)
Background: The skin microbiome, characterized by an overgrowth of Staphylococcus aureus, plays an important role in the pathogenesis of atopic dermatitis (AD). Multidisciplinary treatment in alpine climate is known for its positive effect on disease severity in children with AD and can result in a different immune response compared with...
article 2019
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Atukunda, P. (author), Muhoozi, G.K.M. (author), van den Broek, T.J. (author), Kort, R. (author), Diep, L.M. (author), Kaaya, A.N. (author), Iversen, P.O. (author), Westerberg, A.C. (author)
Background Undernutrition impairs child development outcomes and growth. In this follow-up study of an open cluster-randomized intervention trial we examined the effects of an education package delivered to mothers in rural Uganda on their children's development, growth and gut microbiota at 36 months of age. Methods The parental trial included...
article 2019
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Keijser, B.J.F. (author), Agamennone, V. (author), van den Broek, T.J. (author), Caspers, M. (author), van de Braak, A. (author), Bomers, R. (author), Havekes, M. (author), Schoen, E. (author), van Baak, M. (author), Mioch, D. (author), Bomers, L. (author), Montijn, R.C. (author)
Background: Antibiotic therapy is commonly used in animal agriculture. Antibiotics excreted by the animals can contaminate farming environments, resulting in long term exposure of animals to sub-inhibitory levels of antibiotics. Little is known on the effect of this exposure on antibiotic resistance. In this study, we aimed to investigate the...
article 2019
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Jurburg, S.D. (author), Cornelissen, J.J.B.W.J. (author), de Boer, P. (author), Smits, M.A. (author), Rebel, J.M.J. (author)
Clostridium difficile infections (CDI) are a major cause of antibiotic-associated diarrhea. It is hypothesized that CDI develops due to the antibiotic-induced disruption of the intestinal microbial community structure, which allows C. difficile to flourish. Here, we pre-treated weaned pigs with the antibiotics Clindamycin or Ciprofloxacin for 1...
article 2019
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Reijmer, D. (author)
other 2019
document
Fieten, K.B. (author), Totté, J.E.E. (author), Levin, E. (author), Reyman, M. (author), Meijer, Y. (author), Schuren, F.H.J. (author), Pasmans, S.G.M.A. (author), Pasmans, S.G.M.A. (author)
Background: Exposure to microbes may be important in the development of atopic disease. Atopic diseases have been associated with specific characteristics of the intestinal microbiome. The link between intestinal microbiota and food allergy has rarely been studied, and the gold standard for diagnosing food allergy (double-blind placebo...
article 2018
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Sanz, Y. (author), Romaní-Perez, M. (author), Benítez-Páez, A. (author), Portune, K.J. (author), Brigidi, P. (author), Rampelli, S. (author), Dinan, T. (author), Stanton, C. (author), Delzenne, N. (author), Blachier, F. (author), Neyrinck, A.M. (author), Beaumont, M. (author), Olivares, M. (author), Holzer, P. (author), Günther, K. (author), Wolters, M. (author), Ahrens, W. (author), Claus, S.P. (author), van der Kamp, J.W. (author)
The gut microbiota coexists in partnership with the human host through adaptations to environmental and physiological changes that help maintain dynamic homeostatic healthy states. Break-down of this delicate balance under sustained exposure to stressors (e.g. unhealthy diets) can, however, contribute to the onset of disease. Diet is a key...
article 2018
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Botschuijver, S. (author), Welting, O. (author), Levin, E. (author), Maria-Ferreira, D. (author), Koch, E. (author), Montijn, R.C. (author), Seppen, J. (author), Hakvoort, T.B.M. (author), Schuren, F.H.J. (author), de Jonge, W.J. (author), van den Wijngaard, R.M. (author)
Background: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder associated with altered gastrointestinal microflora and increased nociception to colonic distension. This visceral hypersensitivity can be reversed in our rat maternal separation model by fungicides. Menthacarin® is a proprietary combination of essential oils from...
article 2018
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