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Mcneill, C.R. (author), Asadi, K. (author), Watts, B. (author), Blom, P.W.M. (author), de Leeuw, D.M. (author), TNO Industrie en Techniek (author)The phase-separated structure of blends of the ferroelectric polymer P(VDF-TrFE) and the semiconducting polymer P3HT used in organic non-volatile memories is revealed with soft X-ray spectromicroscopy. These thin-film blends show a columnar morphology, with P3HT-rich columns enclosed in a continuous, essentially pure P(VDF-TrFE) phase favorable...article 2010
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Asadi, K. (author), Li, M. (author), Stingelin, N. (author), Blom, P.W.M. (author), de Leeuw, D.M. (author), TNO Industrie en Techniek (author)Cross-talk in memories using resistive switches in a cross-bar geometry can be prevented by integration of a rectifying diode. We present a functional cross bar memory array using a phase separated blend of a ferroelectric and a semiconducting polymer as storage medium. Each intersection acts simultaneously as a bistable rectifying diode. A...article 2010
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Duarte, F. (author), Wong, S. (author)In this paper, we present a new architecture of the cache-based memory copy hardware accelerator in a multicore system supporting message passing. The accelerator is able to accelerate memory data movements, in particular memory copies. We perform an analytical analysis based on open-queuing theory to study the utilization of our accelerator in...article 2010
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TNO Defensie en Veiligheid (author), van den Steen, M. (author), Brinkman, W.P. (author), Vermetten, E. (author), Neerincx, M. (author)The paper discusses the design and evaluation of a multimedia software application, which can be used in the treatment of combat-related posttraumatic stress disorder (PTSD). The application allows patients and therapist to visualize the patients' past experience using maps, personal photos, stories and selfcreated 3D virtual worlds. The tool...article 2010
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Debucquoy, M. (author), Bode, D. (author), Genoe, J. (author), Gelinck, G.H. (author), Heremans, P. (author), TNO Industrie en Techniek (author)We present an organic charge trapping memory transistor with lithographically defined bottom source and drain contacts. This device can be written and erased at voltages as low as 15 V. More than 500 write and erase cycles and the retention of the trapped charge over more than three months are shown, demonstrating the possibilities of this...article 2009
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Debucquoy, M. (author), Rockelé, M. (author), Genoe, J. (author), Gelinck, G.H. (author), Heremans, P. (author), TNO Industrie en Techniek (author)In this work, we study charge trapping in organic transistor memories with a polymeric insulator as gate dielectric. We found that the mechanism of charge trapping is tunneling from the semiconductor channel into the gate dielectric. Depending on the semiconductor and its processing, charge trapping can result in large bi-directional threshold...article 2009
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Joosen, M.J.A. (author), Jousma, E. (author), van den Boom, T.M. (author), Kuijpers, W.C. (author), Smit, A.B. (author), Lucassen, P.J. (author), van Helden, H.P.M. (author), TNO Defensie en Veiligheid (author)To date, treatment of organophosphate (OP) poisoning shows several shortcomings, and OP-victims might suffer from lasting cognitive deficits and sleep–wake disturbances. In the present study, long-term effects of soman poisoning on learning ability, memory and neurogenesis were investigated in rats, treated with the anticholinergic atropine and...article 2009
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Zekveld, A.A. (author), Kramer, S.E. (author), Kessens, J.M. (author), Vlaming, M.S.M.G. (author), Houtgast, T. (author), TNO Defensie en Veiligheid (author)This study examined the subjective benefit obtained from automatically generated captions during telephone-speech comprehension in the presence of babble noise. Short stories were presented by telephone either with or without captions that were generated offline by an automatic speech recognition (ASR) system. To simulate online ASR, the word...article 2009
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Brouwer, A.-M. (author), Knill, D.C. (author), TNO Defensie en Veiligheid (author)We investigated whether humans use a target's remembered location to plan reaching movements to targets according to the relative reliabilities of visual and remembered information. Using their index finger, subjects moved a virtual object from one side of a table to the other, and then went back to a target. In some trials, the target shifted...article 2009
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Chmielewski, Ł. (author), Hoepman, J.H. (author), van Rossum, P. (author), TNO Informatie- en Communicatietechnologie (author)Human memory is not perfect - people constantly memorize new facts and forget old ones. One example is forgetting a password, a common problem raised at IT help desks. We present several protocols that allow a user to automatically recover a password from a server using partial knowledge of the password. These protocols can be easily adapted to...conference paper 2009
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TNO Informatie- en Communicatietechnologie (author), Li, H. (author)This paper presents a comprehensive statistical analysis of a variety of workloads collected on production clusters and Grids. The applications are mostly computational-intensive and each task requires single CPU for processing data, which dominate the workloads on current production Grid systems. Trace data obtained on a parallel supercomputer...article 2009
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van Linden, S. (author), Cremers, A.H.M. (author), TNO Defensie en Veiligheid (author)The present study investigates the proficiency levels of functionally illiterate persons regarding a number of cognitive skills (language processing skills (reading, writing, listening), visual organizational and visual memory skills, mental spatial orientation, speed of cognitive processing, vigilance, divided attention and perceived self...conference paper 2008
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Heuvelink, A. (author), Klein, M.C.A. (author), Treur, J. (author), TNO Defensie en Veiligheid (author)This paper presents an architecture for a memory model that facilitates versatile reasoning mechanisms over the beliefs stored in an agent's belief base. Based on an approach for belief aggregation, a model is introduced for controlling both the formation of abstract and complex beliefs and the retrieval of them based on their activation history...conference paper 2008
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Heuvelink, A. (author), Klein, M.C.A. (author), Treur, J. (author), TNO Defensie en Veiligheid (author), DenV (author)This paper introduces a formal method to aggregate over basic beliefs, in order to deduce aggregated or complex beliefs as often used in applications. Complex beliefs can represent several things, such as a belief about a period in which other beliefs held or the minimal or maximal certainty with which a belief held. As such they contain richer...conference paper 2008
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Nolte-'t Hoen, E.N.M. (author), Boot, E.P.J. (author), Wagenaar-Hilbers, J.P.A. (author), van Bilsen, J.H.M. (author), Arkesteijn, G.J.A. (author), Storm, G. (author), Everse, L.A. (author), van Eden, W. (author), Wauben, M.H.M. (author), TNO Kwaliteit van Leven (author)Major problems in the analysis of CD4+ effector cell and regulatory T cell (Treg) populations in an activated immune system are caused by the facts that both cell types can express CD25 and that the discriminatory marker forkhead box p3 can only be analyzed in nonviable (permeabilized) cells. Here, we show that CD134 (OX40) can be used as a...article 2008
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van Uffelen, J.G.Z. (author), Chin A Paw, M.J.M. (author), Hopman-Rock, M. (author), van Mechelen, W. (author), TNO Kwaliteit van Leven (author)Objective: To systematically review the effect of physical exercise on cognition in older adults with and without cognitive decline. Data sources: Randomized controlled trials were identified by literature searches in PubMed, EMBASE, CENTRAL, PsycINFO, and AgeLine. Study selection: Papers were included on the basis of predefined inclusion...article 2008
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van Uffelen, J.G.Z. (author), Chinapaw, M.J.M. (author), van Mechelen, W. (author), Hopman-Rock, M. (author), TNO Kwaliteit van Leven (author)Objective: To examine the effects of aerobic exercise or vitamin B supplementation on cognitive function in older adults with mild cognitive impairment (MCI). Design: Randomised placebo-controlled trial. Setting: General community. Participants: Community-dwelling adults aged 70-80 with MCI. Interventions : The 152 participants were randomly...article 2008
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TNO Kwaliteit van Leven (author), Bastiaansen-Jenniskens, Y.M. (author), Koevoet, W. (author), de Bart, A.C.W. (author), Zuurmond, A.M. (author), Bank, R.A. (author), Verhaar, J.A.N. (author), de Groot, J. (author), van Osch, G.J.V.M. (author)Transforming growth factor beta (TGFbeta) is often used in cartilage tissue engineering to increase matrix formation by cells with various phenotypes. However, adverse effects of TGFbeta, such as extensive cross-linking in cultured fibroblasts, have also been reported. Our goal was to study effects of TGFbeta on collagen cross-linking and...article 2008
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TNO Kwaliteit van Leven (author), Abildayeva, K. (author), Berbée, J.F.P. (author), Blokland, A. (author), Jansen, P.J. (author), Hoek, F.J. (author), Meijer, O. (author), Lütjohann, D. (author), Gautier, T. (author), Pillot, T. (author), Vente, J.de (author), Havekes, L.M. (author), Ramaekers, F.C.S. (author), Kuipers, F. (author), Rensen, P.C.N. (author), Mulder, M. (author)The H2 allele of APOC1, giving rise to increased gene expression of apolipoprotein C-I (apoC-I), is in genetic disequilibrium with the APOE4 allele and may provide a major risk factor for Alzheimer's disease (AD). We found that apoC-I protein is present in astrocytes and endothelial cells within hippocampal regions in both human control and AD...article 2008
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TNO Defensie en Veiligheid (author), Maas, A.P.M. (author), van Vliet, F.E. (author)This paper describes the design and performance of a low-cost synthesized FMCW radar module, operating in S band. The bi-layer PCB contains a frequency-agile low phase-noise synthesizer and three identical coherent receive-channels. The transmit channel has an automatic power control system that reduces the output power when a large reflection...conference paper 2008