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van Wijk, R. (author), van der Greef, J. (author), van Wijk, E. (author), TNO Kwaliteit van Leven (author)The relationship between connective tissue and meridian function is discussed in terms of energy transmission. The network of hydrogen-bonded water molecules interspersed within the collagen fibrillar matrix is especially significant for both the sensitivity of connective tissue to weak signals of mechanical pressure, heat, or electricity and...article 2010
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Klein Velderman, M. (author), Crone, M.R. (author), Wiefferink, C.H. (author), Reijneveld, S.A. (author), TNO Kwaliteit van Leven (author)Background: Objective of this study was to assess the degree to which preventive child health professionals (CHPs) identify and act upon psychosocial problems among young toddlers in the general population and to determine the concordance with parent-reported behavioural and emotional problems. Also, associations of psychosocial problems with...article 2010
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Kamphuis, M. (author), Obenhuijsen, N.H. (author), van Dommelen, P. (author), van Buuren, S. (author), Verkerk, P.H. (author), TNO Kwaliteit van Leven (author)The main goal of this guideline for preventive child health care (PCHC) is to improve early detection of disorders that induce short stature. Based on research, evidence-based referral criteria for children aged 0-10 years with a short stature were formulated. These criteria are important for all professionals working with children, such as PCHC...article 2010
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TNO Defensie en Veiligheid (author), Levels, K. (author), Tiemessen, I. (author)Tijdens de marathon van Eindhoven op 11 oktober 2009 er door TNO onderzoek gedaan naar een mogelijk positief effect van het koelen van hardlopers op de loopsnelheid. Het is namelijk bekend dat de efficiëntie van een hardloper afneemt als hij het warm krijgt. Kunnen koude douches dit voorkomen?article 2010
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TNO Defensie en Veiligheid (author), Hoyt, R.W. (author), Buller, M.J. (author), Gunga, H. (author), Werner, A. (author), Sattler, F. (author), Koch, J. (author), Nevola, V.R. (author), Ledderhos, C. (author), Valk, P. (author)Dismounted warfighting groups are increasingly recognizing the benefits of knowing the medical status information that body-worn computerized physiological sensor systems can provide. This report on real-time physiological and psycho-physiological status monitoring reviews: a) Physiological monitoring system architectures, methods for managing...report 2010
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Mihaescu, R. (author), Detmar, S.B. (author), Cornel, M.C. (author), van der Flier, W.M. (author), Heutink, P. (author), Hol, E.M. (author), Rikkert, M.G.M.O. (author), van Duijn, C.M. (author), Janssens, A.C.J.W. (author), TNO Kwaliteit van leven (author)Alzheimer's disease (AD) is the most prevalent form of dementia and the number of cases is expected to increase exponentially worldwide. Three highly penetrant genes (AβPP, PSEN1, and PSEN2) explain only a small number of AD cases with a Mendelian transmission pattern. Many genes have been analyzed for association with non-Mendelian AD, but the...article 2010
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TNO Kwaliteit van Leven (author), Altorf, W. (author), van der Kuil, W.A. (author), Engberink, M.F. (author), Brink, E.J. (author), van Baak, M.A. (author), Bakker, S.J.L. (author), Navis, G. (author), van't Veer, P. (author), Geleijnse, J.M. (author)Background: Elevated blood pressure (BP), which is a major risk factor for cardiovascular disease, is highly prevalent worldwide. Recently, interest has grown in the role of dietary protein in human BP. We performed a systematic review of all published scientific literature on dietary protein, including protein from various sources, in relation...article 2010
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Groenewoud, C.L. (author), Schoen, E.D. (author), Malone, K.M. (author), Jonkers, E. (author), Hoedemaeker, D.M. (author), Hogema, J.H. (author)Naturalistic driving observation is a relatively new method for studying road safety issues, a method by which one can objectively observe various driver- and accident related behaviour. Typically, participants get their own vehicles equipped with some sort of data logging device that can record various driving behaviours such as speed, braking,...report 2010
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- TNO Defensie en Veiligheid (author), Binsch, O. (author) doctoral thesis 2010
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TNO Kwaliteit van Leven (author), Matthys, C. (author), Bucchini, L. (author), Busstra, M.C. (author), Cavelaars, A.E.J.M. (author), Eleftheriou, P. (author), Garc?a-Alvarez, A. (author), Fairweather-Tait, S. (author), Gurinovi?, M. (author), van Ommen, B. (author), Contor, L. (author)Approaches through which reference values for micronutrients are derived, as well as the reference values themselves, vary considerably across countries. Harmonisation is needed to improve nutrition policy and public health strategies. The EURRECA (EURopean micronutrient RECommendations Aligned, http://www.eurreca.org) Network of Excellence is...article 2010
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Kong, H. (author), Wang, M. (author), Venema, K. (author), Maathuis, A. (author), van der Heijden, R. (author), van der Greef, J. (author), Xu, G. (author), Hankemeier, T. (author), TNO Kwaliteit van Leven (author)A high-performance liquid chromatography-high resolution Fourier transform ion cyclotron resonance mass spectrometry (HPLC-FTICR-MS) method was developed to investigate the metabolism of ginsenosides in in vitro models of the gastro-intestinal tract. The metabolites were identified by high-resolution tandem mass spectrometry. Degradation and...article 2009
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Wang, J. (author), van der Heijden, R. (author), Spijksma, G. (author), Reijmers, T. (author), Wang, M. (author), Xu, G. (author), Hankemeier, T. (author), van der Greef, J. (author), TNO Kwaliteit van Leven (author)A matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) method was developed for the high throughput and robust qualitative profiling of alkaloids in Fuzi-the processed lateral roots of the Chinese herbal medicine Aconitum carmichaeli Debx (A. carmichaeli). After optimization, powdered roots - without any further sample...article 2009
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TNO Kwaliteit van Leven (author), Gaisser, S. (author), Vignola-Gagné, E. (author), Hüsing, B. (author), Enzing, C. (author), van der Valk, T. (author)Against the background of a number of first drug-diagnostic co-products developed and introduce into the European market, European decision-makers feel impelled to react and position themselves in the field of personalized medicine. Their reactions cover a broad range, from the analysis of knowledge requirements for market approval to the need...article 2009
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Ashwell, M. (author), Lambert, J.P. (author), Alles, M.S. (author), Branca, F. (author), Bucchini, L. (author), Brzozowska, A. (author), de Groot, L.C.P.G.M. (author), Dhonukshe-Rutten, R.A.M. (author), Dwyer, J.T. (author), Fairweather-Tait, S. (author), Koletzko, B. (author), Pavlovic, M. (author), Raats, M.M. (author), Serra-Majem, L. (author), Smith, R. (author), van Ommen, B. (author), Veer, P.V. (author), Von Rosen, J. (author), Pijls, L.T.J. (author), TNO Kwaliteit van Leven (author)Background: There is considerable variation in the recommended micronutrient intakes used by countries within Europe, partly due to different methodologies and concepts used to determine requirements and different approaches used to express the recommendations. As populations become more mobile and multi-national, and more traditional foods...article 2008
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Fransman, W. (author), Schinkel, J. (author), Meijster, T. (author), van Hemmen, J. (author), Tielemans, E. (author), Goede, H. (author), TNO Kwaliteit van Leven (author)Objectives: This paper describes the development and evaluation of an evidence database on the effectiveness of risk management measures (RMMs) to control inhalation exposure. This database is referred to as Exposure Control Efficacy Library (ECEL). Methods: A comprehensive review of scientific journals in the occupational hygiene field was...article 2008
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Nooij, S.A.E. (author), Bos, J.E. (author), Groen, E.L. (author), TNO Defensie en Veiligheid (author)Adaptation to a novel gravitational state involves adaptation of vestibular mediated responses, in particular those mediated by the otolith organs. The present paper investigates whether the orientation of Listings plane, which is under control of otolith signals, is affected by sustained exposure to hypergravity. Subjects were exposed to four...article 2008
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Hosli, E.J. (author), Elsinga, J. (author), Buitendijk, S.E. (author), Assendelft, W.J.J. (author), van der Pal-de Bruin, K.M. (author), TNO Kwaliteit van Leven (author)Aims: Information about risk factors and preventive measures given before conception is estimated to prevent 15-35% of adverse pregnancy outcomes. We aimed to identify women's motives for not responding to an invitation for preconception counseling (PCC) from their general practitioner. Methods: A purposive sample of 11 women who did not respond...article 2008
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- TNO Kwaliteit van Leven (author), Binnendijk, D. (author) article 2008
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Balk, A.H. (author), Davidse, W. (author), van Dommelen, P. (author), Klaassen, E. (author), Caliskan, K. (author), van der Burgh, P. (author), Leenders, C.M. (author), TNO Kwaliteit van Leven (author), KvL (author)Background: New strategies are required to optimize care in increasing numbers of chronic heart failure patients. The aim of this randomised trial was to evaluate a remote guidance system. Methods: Intervention group patients received a home TV-channel providing educational materials. Tele-guidance was performed by a Medical Service Centre....article 2008
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TNO Kwaliteit van Leven (author), de Boer, W.E.L. (author), Donceel, P. (author), Brage, S. (author), Rus, M. (author), Willems, J.H.B.M. (author)Background. Decisions on disability pensions are based, among others, on medical reports. The way these medical assessments are performed is largely unclear. The aim of the study was to determine which grounds are used by social insurance physicians (SIPs) in these assessments and to determine if the identification of these grounds can help...article 2008