Searched for: subject%3A%22Mass%255C%2Bspectrometer%22
(1 - 12 of 12)
document
Tromp, P.C. (author), Kuijpers, E. (author), Bekker, C. (author), Godderis, L. (author), Lan, Q. (author), Jedynska, A.D. (author), Vermeulen, R. (author), Pronk, A. (author)
To date there is no consensus about the most appropriate analytical method for measuring carbon nanotubes (CNTs), hampering the assessment and limiting the comparison of data. The goal of this study is to develop an approach for the assessment of the level and nature of inhalable multi-wall CNTs (MWCNTs) in an actual workplace setting by...
article 2017
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de Marchi, T. (author), Braakman, R.B.H. (author), Stingl, C. (author), van Duijn, M.M. (author), Smid, M. (author), Foekens, J.A. (author), Luider, T.M. (author), Martens, J.W.M. (author), Umar, A. (author)
article 2016
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Peters, R.J.B. (author), van Bemmel, G. (author), Herrera-Rivera, Z. (author), Helsper, H.P.F.G. (author), Marvin, H.J.P. (author), Weigel, S. (author), Tromp, P.C. (author), Oomen, A.G. (author), Rietveld, A.G. (author), Bouwmeester, H. (author)
Titanium dioxide (TiO2) is a common food additive used to enhance the white color, brightness, and sometimes flavor of a variety of food products. In this study 7 food grade TiO2 materials (E171), 24 food products, and 3 personal care products were investigated for their TiO 2 content and the number-based size distribution of TiO2 particles...
article 2014
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Kong, H. (author), Wang, M. (author), Venema, K. (author), Maathuis, A. (author), van der Heijden, R. (author), van der Greef, J. (author), Xu, G. (author), Hankemeier, T. (author), TNO Kwaliteit van Leven (author)
A high-performance liquid chromatography-high resolution Fourier transform ion cyclotron resonance mass spectrometry (HPLC-FTICR-MS) method was developed to investigate the metabolism of ginsenosides in in vitro models of the gastro-intestinal tract. The metabolites were identified by high-resolution tandem mass spectrometry. Degradation and...
article 2009
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Wang, J. (author), van der Heijden, R. (author), Spijksma, G. (author), Reijmers, T. (author), Wang, M. (author), Xu, G. (author), Hankemeier, T. (author), van der Greef, J. (author), TNO Kwaliteit van Leven (author)
A matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) method was developed for the high throughput and robust qualitative profiling of alkaloids in Fuzi-the processed lateral roots of the Chinese herbal medicine Aconitum carmichaeli Debx (A. carmichaeli). After optimization, powdered roots - without any further sample...
article 2009
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Bobeldijk, I. (author), Hekman, M. (author), van der Vries de- Weij, J. (author), Coulier, L. (author), Ramaker, R. (author), Kleemann, R. (author), Kooistra, T. (author), Rubingh, C. (author), Freidig, A. (author), Verheij, E. (author), TNO Kwaliteit van Leven (author)
We report a sensitive, generic method for quantitative profiling of bile acids and other endogenous metabolites in small quantities of various biological fluids and tissues. The method is based on a straightforward sample preparation, separation by reversed-phase high performance liquid-chromatography mass spectrometry (HPLC-MS) and electrospray...
article 2008
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Bobeldijk, I. (author), Karlsson, D. (author), Pronk, A. (author), Gonsalves, J. (author), Hekman, M. (author), van de Lagemaat, D. (author), Preller, L. (author), Heederik, D. (author), Skarping, G. (author), TNO Kwaliteit van Leven (author)
An adapted method for the quantitative determination of isocyanates in air was implemented and validated in-house. The method was based on air sampling using an impinger flask containing di-n-butylamine (DBA) in toluene and a glass fibre filter in series. The DBA derivatives were determined using liquid chromatography and tandem mass...
article 2008
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TNO Defensie en Veiligheid (author), van Wuijckhuijse, A.L. (author), Stowers, M.A. (author), Kleefsman, W.A. (author), van Baar, B.L.M. (author), Kients, C.E. (author), Marijnissen, J.C.M. (author)
A new aerosol time-of-flight mass spectrometer (ATOFMS) was developed for the near real-time analysis of single bioaerosol particles. The system combines ATOFMS with laser-induced fluorescence selection and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. The influences of laser power and sample preparation on the quality...
article 2005
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van der Greef, J. (author), Stroobant, P. (author), van der Heijden, R. (author), TNO Voeding (author)
Medical systems biology has generated widespread interest because of its bold conception and exciting potential, but the field is still in its infancy. Although there has been tremendous progress achieved recently in generating, integrating and analysing data in the medical and pharmaceutical field, many challenges remain, especially with...
article 2004
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Schellen, A. (author), Ooms, B. (author), van de Lagemaat, D. (author), Vreeken, R. (author), van Dongen, W.D. (author), TNO Voeding (author)
A generic method was developed for the fast determination of a wide range of drugs in serum or plasma. The methodology comprises generic solid-phase extraction, on-line coupled to gradient HPLC with tandem mass spectrometric detection (SPE-LC-MS/MS). The individual components of the SPE-LC-MS/MS system were optimized in an integrated approach to...
article 2003
document
Kievit, O. (author), Busker, R.W. (author), Kientz, C.E. (author), Marijnissen, J.C.M. (author)
This paper describes the latest achievements in the development of a new rapid detector for biological warfare agents (BWA). The system uses aerodynamic particle sizing and matrix-assisted laser desorption/ionisation aerosol time-of-flight mass spectrometry (MALDI ATOFMS) to analyse individual aerosol particles sampled directly from the...
article 2003
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Elliott, C.T. (author), Baxter, G.A. (author), Hewitt, S.A. (author), Arts, C.J.M. (author), van Baak, M. (author), Hellenäs, K.-E. (author), Johannson, A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The drug salbutamol (SBL) is a β-agonist that may be used illegally as an animal growth promoter. SBL is also a good example of a drug which is excreted in the form of glucuronides and sulfates. Such metabolites cause complexities in analysing for the presence of drug residues. In the majority of cases a process of deconjugation and sample clean...
article 1998
Searched for: subject%3A%22Mass%255C%2Bspectrometer%22
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