Searched for: subject%3A%22Magnetism%22
(81 - 100 of 173)

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Usta, M. (author), Wortelboer, H.M. (author), Vervoort, J. (author), Boersma, M.G. (author), Rietjens, I.M.C.M. (author), van Bladeren, P.J. (author), Cnubben, N.H.P. (author), TNO Kwaliteit van Leven (author)
Curcumin, an α,β-unsaturated carbonyl compound, reacts with glutathione, leading to the formation of two monoglutathionyl curcumin conjugates. In the present study, the structures of both glutathione conjugates of curcumin were identified by LC-MS and one- and two-dimensional 1H NMR analysis, and their formation in incubations with human...
article 2007
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Schoonen, W.G.E.J. (author), Kloks, C.P.A.M. (author), Ploemen, J.P.H.T.M. (author), Horbach, G.J. (author), Smit, M.J. (author), Zandberg, P. (author), Mellema, J.R. (author), van Zuylen, C.T. (author), Tas, A.C. (author), van Nesselrooij, J.H.J. (author), Vogels, J.T.W.E. (author), TNO Kwaliteit van Leven (author)
1H nuclear magnetic resonance (NMR) spectroscopy of rat urine in combination with pattern recognition analysis was evaluated for early noninvasive detection of toxicity of investigational chemical entities. Bromobenzene (B) and paracetamol (P) were administered at five single oral dosages between 2 and 500 mg/kg and between 6 and 1800 mg/kg,...
article 2007
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Hunter, D.J. (author), Li, J. (author), LaValley, M. (author), Bauer, D.C. (author), Nevitt, M. (author), de Groot, J. (author), Poole, R. (author), Eyre, D. (author), Guermazi, A. (author), Gale, D. (author), Felson, D.T. (author), TNO Kwaliteit van Leven (author)
We used data from a longitudinal observation study to determine whether markers of cartilage turnover could serve as predictors of cartilage loss on magnetic resonance imaging (MRI). We conducted a study of data from the Boston Osteoarthritis of the Knee Study (BOKS), a completed natural history study of knee osteoarthritis (OA). All subjects in...
article 2007
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Nardes, A.M. (author), Kemerink, M. (author), Janssen, R.A.J. (author), Bastiaansen, J.J.A.M. (author), Kiggen, N.M.M. (author), Langeveld, B.M.W. (author), van Breemen, A.J.J.M. (author), de Kok, M.M. (author), TNO Industrie en Techniek (author)
The anisotropic conductivity of spin-coated poly(3,4- ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) thin films by temperature-dependent conductivity measurements, has been analyzed. A detailed 3D morphological model was derived from topographic scanning tunneling microscopy (STM) and cross-sectional atomic force microscopy (AFM)...
article 2007
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Franke, C. (author), Pennock, G.M. (author), Drury, M.R. (author), Engelmann, R. (author), Lattard, D. (author), Garming, J.F.L. (author), von Dobeneck, T. (author), Dekkers, M.J. (author), TNO Bouw en Ondergrond (author)
In paleomagnetic and environmental magnetic studies the magnetomineralogical identification is usually based on a set of rock magnetic parameters, complemented by crystallographic and chemical information retrieved from X-ray diffraction (XRD), (electron) microscopy or energy dispersive spectroscopy (EDS) of selected samples. While very useful,...
article 2007
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Schoonen, W.G.E.J. (author), Kloks, C.P.A.M. (author), Ploemen, J.-P.H.T.M. (author), Smit, M.J. (author), Zandberg, P. (author), Horbach, G.J. (author), Mellema, J.-R. (author), van Zuylen, C.T. (author), Tas, A.C. (author), van Nesselrooij, J.H.J. (author), Vogels, J.T.W.E. (author), TNO Kwaliteit van Leven (author)
A procedure of nuclear magnetic resonance (NMR) urinalysis using pattern recognition is proposed for early detection of toxicity of investigational compounds in rats. The method is applied to detect toxicity upon administration of 13 toxic reference compounds and one nontoxic control compound (mianserine) in rats. The toxic compounds are...
article 2007
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Garming, J.F.L. (author), Von Dobeneck, T. (author), Franke, C. (author), Bleil, U. (author), TNO Bouw en Ondergrond (author)
With various low-temperature experiments performed on magnetic mineral extracts of marine sedimentary deposits from the Argentine continental slope near the Rio de la Plata estuary, a so far unreported style of partial magnetic self-reversal has been detected. In these sediments the sulphate-methane transition (SMT) zone is situated at depths...
article 2007
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Barrell, Y. (author), Naus, H.W.L. (author), TNO Defensie en Veiligheid (author)
Detection and localisation of hidden magnetic objects is studied. The concomitant disturbance of the earth magnetic field is exploited. Magnetic fields and or gradients are measured with a number of sensors. Two point models for magnetic fields are selected for the analysis: the magnetic dipole and its quadrupole extension. It is shown how to...
article 2007
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Egert, M. (author), de Graaf, A.A. (author), Maathuis, A. (author), de Waard, P. (author), Plugge, C.M. (author), Smidt, H. (author), Deutz, N.E.P. (author), Dijkema, C. (author), de Vos, W.M. (author), Venema, K. (author), TNO Kwaliteit van Leven (author)
16S rRNA-based stable isotope probing (SIP) and nuclear magnetic resonance (NMR) spectroscopy-based metabolic profiling were used to identify bacteria fermenting glucose under conditions simulating the human intestine. The TIM-2 in vitro model of the human intestine was inoculated with a GI tract microbiota resembling that of the small intestine...
article 2007
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Hunter, D.J. (author), LaValley, M. (author), Li, J. (author), Zhang, Y. (author), Bauer, D. (author), Nevitt, M. (author), Guermazi, A. (author), de Groot, J. (author), Sakkee, N. (author), Gale, D. (author), Felson, D.T. (author), TNO Kwaliteit van Leven (author)
Objective: Age-related changes in articular cartilage are likely to play a role in the etiology of osteoarthritis (OA). One of the major changes in the extracellular matrix of cartilage is the age-related accumulation of advanced glycation end products (AGEs). Pentosidine, an AGE crosslink, is one of the few characterized AGEs and is considered...
article 2007
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TNO Kwaliteit van Leven (author), Alkemade, F.E. (author), de Gittenberger-Groot, A.C. (author), Schiel, A.E. (author), van Munsteren, J.C. (author), Hogers, B. (author), van Vliet, L.S.J. (author), Poelmann, R.E. (author), Havekes, L.M. (author), van Dijk, K.W. (author), de Ruiter, M.C. (author)
OBJECTIVE - Maternal hypercholesterolemia is associated with a higher incidence and faster progression of atherosclerotic lesions in neonatal offspring. We aimed to determine whether an in utero environment exposing a fetus to maternal hypercholesterolemia and associated risk factors can prime the murine vessel wall to accelerated development of...
article 2007
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TNO Industrie en Techniek (author), van den Dool, T.C. (author), Kamphues, F.G. (author), Gielesen, W.L.M. (author), Braam, B.C. (author), Loix, N. (author), Kooijman, P.P. (author), Velsink, G. (author), Stockman, Y. (author), Benoit, J. (author), Sève, F. (author)
TNO has developed a compact BreadBoard (BB) cryogenic Optical Delay Line (ODL) for use in future space interferometry missions such as ESA's Darwin and NASA's TPF-I. The breadboard delay line is representative of a flight mechanism. The optical design is a two-mirror cat's-eye. A linear guiding system based on magnetic bearings provides...
conference paper 2007
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van der Greef, J. (author), Hankemeier, T. (author), McBurney, R.N. (author), TNO Kwaliteit van Leven (author)
Personalized medicine - defined as customized medical care for each patient's unique condition - in the broader context of personalized health, will make significant strides forward when a systems approach is implemented to achieve the ultimate in disease phenotyping and to create novel therapeutics that address system-wide molecular...
article 2006
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Smeets, P.A.M. (author), de Graaf, C. (author), Stafleu, A. (author), van Osch, M.J.P. (author), Nievelstein, R.A.J. (author), van der Grond, J. (author), TNO Kwaliteit van Leven (author)
Background: The brain plays a crucial role in the decision to eat, integrating multiple hormonal and neural signals. A key factor controlling food intake is selective satiety, ie, the phenomenon that the motivation to eat more of a food decreases more than does the motivation to eat foods not eaten. Objective: We investigated the effect of...
article 2006
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Zehner, G.F. (author), Hudson, J.A. (author), Oudenhuijzen, A. (author), TNO Defensie en Veiligheid (author)
From 1997 through 2002, the Air Force Research Lab and TNO Defence, Security and Safety (Business Unit Human Factors) were involved in a series of tests to quantify the accuracy of five Human Modeling Systems (HMSs) in determining accommodation limits of ejection seat aircraft. The results of these tests indicated that baseline information on...
conference paper 2006
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van den Dool, T.C. (author), Kamphues, F.G. (author), Gielesen, W.L.M. (author), Benoit, J. (author), Laurenceau, E. (author), Poupinet, A. (author), Sève, F. (author), Stockman, Y. (author), Fleury, K. (author), Loix, N. (author), Kooijman, P.P. (author), de Vries, C. (author), van Weers, H. (author), Velsink, G. (author)
TNO, in co-operation with Micromega-Dynamics, SRON, Dutch Space and CSL, has designed a compact breadboard cryogenic delay line (figure 1) for use in future space interferometry missions. The breadboard (BB) delay line is representative of a flight mechanism. The delay line has a single stage voice coil actuator for Optical Path Difference (OPD)...
conference paper 2006
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TNO Industrie en Techniek (author), Hamelinck, R.F.M.M. (author), Rosielle, P.C.J.N. (author), Steinbuch, M. (author), Ellenbroek, R.M.L. (author), Verhaegen, M. (author), Doelman, N.J. (author)
In the design of a large adaptive deformable membrane mirror, variable reluctance actuators are used. These consist of a closed magnetic circuit in which a strong permanent magnet provides a static magnetic force on a ferromagnetic core which is suspended in a membrane. By applying a current through the coil which is situated around the magnet,...
conference paper 2006
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Rieckmann, P. (author), Kruse, N. (author), Nagelkerken, L. (author), Beckmann, K. (author), Miller, D. (author), Polman, C. (author), Dahlke, F. (author), Toyka, K.V. (author), Hartung, H.P. (author), Stürzebecher, S. (author), TNO Preventie en Gezondheid (author)
Background: Subcutaneous IFNβ-1b (Betaferon®) is an established immunomodulatory treatment for relapsing remitting MS and active secondary progressive multiple sclerosis (SPMS). It modulates cytokine and adhesion molecule expression but long term in vivo effects of IFNβ-1b on the immune system are not known in multiple sclerosis. Objective: To...
article 2005
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Smeets, P.A.M. (author), de Graaf, C. (author), Stafleu, A. (author), van Osch, M.J.P. (author), van der Grond, J. (author), TNO Kwaliteit van Leven (author)
Background: Evidence exists that beverages do not trigger appropriate anticipatory physiologic responses, such as cephalic phase insulin release. Therefore, it is of interest to elucidate the food properties necessary for triggering adaptive responses. Previously, we found a prolonged dose-dependent decrease in the hypothalamic functional...
article 2005
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Jansen, J.J. (author), Hoefsloot, H.C.J. (author), van der Greef, J. (author), Timmerman, M.E. (author), Smilde, A.K. (author), TNO Kwaliteit van Leven (author)
Genomics-based technologies in systems biology have gained a lot of popularity in recent years. These technologies generate large amounts of data. To obtain information from this data, multivariate data analysis methods are required. Many of the datasets generated in genomics are multilevel datasets, in which the variation occurs on different...
article 2005
Searched for: subject%3A%22Magnetism%22
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